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Sökning: WFRF:(Howlett Robert)

  • Resultat 1-9 av 9
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2.
  • Bocken, Nancy M.P., et al. (författare)
  • Circular business model experimentation : Concept and approaches
  • 2019
  • Ingår i: Sustainable Design and Manufacturing - Proceedings of the 5th International Conference on Sustainable Design and Manufacturing KES-SDM-18. - Cham : Springer International Publishing. - 2190-3018 .- 2190-3026. - 9783030042899 ; 130, s. 239-250
  • Konferensbidrag (refereegranskat)abstract
    • This paper aims to provide conceptual insight on ‘Circular business model experimentation’ by exploring the concept and potential approaches to pursue. The Circular Economy can be a successful driver for change by focusing efforts on economic and environmental issues while also addressing socio-economic challenges such as (un)employment. The business model of firms is viewed as a systematic driver for change in a company, bringing together the various elements of the way of doing business: the value proposition (what value is proposed and to whom); value creation and delivery (how this value is provided) and value capture (how money is made and other forms of value are captured). To develop and validate novel business models, experimentation is needed. While experimentation has been prominent in natural sciences, economics and transitions management literature, it has not yet mainstreamed as a potential business approach, despite the fact that it has been heralded as a key driver for competitiveness and sustainability success. This paper explores the concept of Circular Business Model Experimentation by addressing the following questions: What is Circular Business Model Experimentation? What approaches are available for business? Based on this, suggestions for future research and practice on circular business model experimentation are developed.
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3.
  • Bocken, Nancy, et al. (författare)
  • Slowing resource loops in the circular economy : An experimentation approach in fashion retail
  • 2019
  • Ingår i: Sustainable Design and Manufacturing - Proceedings of the 5th International Conference on Sustainable Design and Manufacturing KES-SDM-18. - Cham : Springer International Publishing. - 2190-3026 .- 2190-3018. - 9783030042899 ; 130, s. 164-173
  • Konferensbidrag (refereegranskat)abstract
    • The Circular Economy is viewed as an important driver for resolving resource issues and tackling sustainability issues more broadly. The fashion industry operates in a largely linear way and suffers from various environmental, societal and economic challenges. In a Circular Economy, first and foremost, products need to be retained at the highest level, thus slowing resource loops. Slowing resource loops goes against current fast fashion trends and therefore appears the most difficult approach to pursue. This paper investigates how a large established retailer aims to slow resource loops as part of a broader project targeted to significantly reduce textile waste to landfill. The retailer collaborated with a university partner to pursue circular business model experiments. This paper reports on the approach for a slowing resource loops experiment around building sewing capabilities. Suggestions for future research and practice on circular business model experimentation are included.
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4.
  • Mahdiraji, Saeid Amouzad, et al. (författare)
  • An Optimization Model for the Tradeoff Between Efficiency and Equity for Mobile Stroke Unit Placement
  • 2021
  • Ingår i: Innovation in Medicine and Healthcare. - Singapore : Springer. - 2190-3026 .- 2190-3018. - 9789811630125 - 9789811630132 ; , s. 183-193
  • Konferensbidrag (refereegranskat)abstract
    • A mobile stroke unit (MSU) is an ambulance, where stroke patients can be diagnosed and treated. Recently, placement of MSUs has been studied focusing on either maximum population coverage or equal service for all patients, termed efficiency and equity, respectively. In this study, we propose an unconstrained optimization model for the placement of MSUs, designed to introduce a tradeoff between efficiency and equity. The tradeoff is based on the concepts of weighted average time to treatment and the time difference between the expected time to treatment for different geographical areas. We conduct a case-study for Sweden’s Southern Health care Region (SHR), generating three scenarios (MSU1, MSU2, and MSU3) including 1, 2, and 3 MSUs, respectively. We show that our proposed optimization model can tune the tradeoff between the efficiency and equity perspectives for the MSU(s) allocation. This enables a high level of equal service for most inhabitants, as well as reducing the time to treatment for most inhabitants of a geographic region. In particular, placing three MSUs in the SHR with the proposed tradeoff, the share of inhabitants who are expected to receive treatment within an hour potentially improved by about a factor of 14 in our model.
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5.
  • Petzold, Axel, et al. (författare)
  • Diagnosis and classification of optic neuritis
  • 2022
  • Ingår i: Lancet Neurology. - : ELSEVIER SCIENCE INC. - 1474-4422 .- 1474-4465. ; 21:12, s. 1120-1134
  • Forskningsöversikt (refereegranskat)abstract
    • There is no consensus regarding the classification of optic neuritis, and precise diagnostic criteria are not available. This reality means that the diagnosis of disorders that have optic neuritis as the first manifestation can be challenging. Accurate diagnosis of optic neuritis at presentation can facilitate the timely treatment of individuals with multiple sclerosis, neuromyelitis optica spectrum disorder, or myelin oligodendrocyte glycoprotein antibody-associated disease. Epidemiological data show that, cumulatively, optic neuritis is most frequently caused by many conditions other than multiple sclerosis. Worldwide, the cause and management of optic neuritis varies with geographical location, treatment availability, and ethnic background. We have developed diagnostic criteria for optic neuritis and a classification of optic neuritis subgroups. Our diagnostic criteria are based on clinical features that permit a diagnosis of possible optic neuritis; further paraclinical tests, utilising brain, orbital, and retinal imaging, together with antibody and other protein biomarker data, can lead to a diagnosis of definite optic neuritis. Paraclinical tests can also be applied retrospectively on stored samples and historical brain or retinal scans, which will be useful for future validation studies. Our criteria have the potential to reduce the risk of misdiagnosis, provide information on optic neuritis disease course that can guide future treatment trial design, and enable physicians to judge the likelihood of a need for long-term pharmacological management, which might differ according to optic neuritis subgroups.
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6.
  • Qu, Xiaobo, 1983, et al. (författare)
  • Preface
  • 2019
  • Ingår i: Smart Innovation, Systems and Technologies. - 2190-3026 .- 2190-3018. ; 149, s. vii-vii
  • Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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7.
  • Qu, Xiaobo, 1983, et al. (författare)
  • Preface
  • 2020
  • Ingår i: Smart Innovation, Systems and Technologies. - 2190-3026 .- 2190-3018. ; 185, s. v-v
  • Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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8.
  • Qu, Xiaobo, 1983, et al. (författare)
  • Preface
  • 2021
  • Ingår i: Smart Innovation, Systems and Technologies. - 2190-3026 .- 2190-3018. ; 231, s. v-vi
  • Konferensbidrag (övrigt vetenskapligt/konstnärligt)
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