| 1. |
- Berglin, Lena, et al.
(författare)
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Interaction Design Methods in Fashion Design Teaching
- 2007
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Ingår i: The Nordic Textile Journal 2006-07, p. 26-51. - : University College of Borås. The Swedish School of Textiles.
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- The expressiveness of use is of focal interest in fashion design, which makes the perspective of act design important in learning/teaching. The objective of the project presented here was to introduce interaction design methods in fashion design teaching to make act design explicit throughout the different stages of the design process in a systematic manner; to develop a general workshop curriculum in experimental fashion design focusing on the expressiveness of wearing and use. A series of test workshops were implemented to provide a foundation for reflection and critical discussions. The main results, motivated by workshop evaluations, consist of theoretical models for a systematic development of workshop exercises in fashion design aesthetics.
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| 2. |
- Jönsson, Lina, et al.
(författare)
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Effects of hybrid and dietary mussel meal on broiler performance during 10 weeks of rearing
- 2016
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Ingår i: Annual meeting of the European Association for Animal Production. - 1382-6077. ; , s. 564-564
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- Organic broiler production is characterised by a long rearing period (>10 weeks) and diets based on locally available feedstuff. Until recently, conventional fast growing broilers hybrids have been used exclusively in organic broiler production in Sweden. Rearing fast growing hybrids during long periods has resulted in e.g. ascites and leg disorders and the need for alternative slow growing hybrids for these production systems has been outspoken. Moreover, the nutrient composition (especially protein quality) in the organic diets does not meet the high demands of the conventional fast growing hybrid. This study investigated broiler production performance in the fast growing hybrid Ross 308 (R) and the slower growing hybrid Rowan Ranger (RR) fed either a standard organic diet (O, 11.3 MJ ME and 164 g protein/kg feed) or an organic diet with mussel meal as protein source (M, 11.2 MJ ME and 156 g protein/kg feed) during a 10 weeks rearing period. The study included in total 389 birds housed in groups of 20-21 birds per group divided over the treatment combinations; 5 RO, 4 RM, 5 RRO and 4 RRM groups. During the rearing period, 22 birds were culled due to leg weakness and 16 died or were culled due to other reasons. The statistical analyses were performed with linear mixed models in SAS. Preliminary results indicated that R birds grew faster when fed the mussel meal diet while this difference in the response to protein quality was less pronounces in RR birds (4,586a±55.3, 3,961b±49.5, 2,919c±55.3 and 2,891c±49.5 g live weight at 71 d in the RM, RO, RRM and RRO treatment respectively, LSM±SE; different subscript letters indicate pairwise differences of P<0.05). A significantly higher proportion of RM birds were culled due to leg weakness compared to the other treatments (P<0.05). Dressing percentage was higher in R than RR birds (P<0.05), but there were no effect of diet treatment.
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| 3. |
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| 4. |
- Adelmann, Kenneth, et al.
(författare)
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Språkutveckling, medier och demokrati
- 2014
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Ingår i: Medie- och informationskunnighet i Norden. - Göteborg : Nordicom. - 9789186523886 ; , s. 117-129
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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| 5. |
- Adelmann, Kent, et al.
(författare)
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Språkutveckling, medier och demokrati
- 2014
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Ingår i: Medie- och informationskunnighet i Norden. - : Nordicom. - 9789186523886 ; , s. 117-121
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- Vi som har skrivit denna artikel är alla verksamma inom forskningsmiljön Svenska med didaktisk inriktning (SMDI) vid Malmö högskola. Frågor om språkutveckling i bred bemärkelse står här i centrum. För närvarande är vi engagerade i projektet ”SMDI och lärande i medielandskapet 2.0”. Vår teoretiska plattform kan beskrivas som medieekologisk, vilket kortfattat uttryckt innebär att vi är intresserade av de mångfaldiga och komplexa relationerna mellan medier och kommunikativa kompetenser (Elmfeldt & Erixon 2007; Erixon 2012; Hayles 2002). Dessa relationer förstås därför inte, som så ofta annars i skolsammanhang, i termer av enkelriktad påverkan eller effekter (exempelvis datorns och internets negativa inverkan på skriftspråket). Vår huvudpoäng i denna artikel är att medie- och informationskunnighet, MIK, handlar om, borde handla om, framför allt två saker: språkutveckling och demokrati.
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| 6. |
- Ahrenberg, Lars, 1948-, et al.
(författare)
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Studying Disability Related Terms with Swe-Clarin Resources
- 2019
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Konferensbidrag (refereegranskat)abstract
- In Swedish, as in other languages, the words used to refer to disabilities and people with disabilities are manifold. Recommendations as to which terms to use have been changed several times over the last hundred years. In this exploratory paper we have used textual resources provided by Swe-Clarin to study such changes quantitatively. We demonstrate that old and new recommendations co-exist for long periods of time, and that usage sometimes converges.
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| 7. |
- Allan, Julie, et al.
(författare)
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Etiska perspektiv på specialpedagogers yrkesroll och värdepedagogiska praktik
- 2022
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Bok (övrigt vetenskapligt/konstnärligt)abstract
- Yrkesetik handlar om att hantera motstridiga värden på ett professionellt sätt. Olika dilemman är ständigt närvarande i skolans vardag och kan handla om att minimera risken för att elever ska exkluderas eller om att säkerställa att elever får möjlighet att visa sina kunskaper på rätt sätt. I sin yrkesroll ställs specialpedagogen inför mångfacetterade arbetsuppgifter som omfattar att stödja barn och elever i svårigheter, vara en kvalificerad samtalspartner i pedagogiska frågor och samverka med andra yrkesgrupper för att utveckla skolans verksamhet. Arbetet innebär val mellan olika handlingsalternativ som kräver både kunskap och förmåga att urskilja och värdera etiska aspekter i komplexa sammanhang. I boken diskuteras både dilemman och möjligheter där etiska perspektiv spelar en viktig roll. Kapitlen tar upp frågor med praktiknära innehåll som lämpar sig för såväl individuell reflektion som kollegiala samtal med syftet att skapa ett gemensamt yrkesetiskt språk. Boken vänder sig till blivande och praktiserande specialpedagoger samt andra yrkeskategorier med arbetsuppgifter inom det specialpedagogiska området.
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| 8. |
- Betancourt, Lazaro Hiram, et al.
(författare)
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Improved survival prognostication of node-positive malignant melanoma patients utilizing shotgun proteomics guided by histopathological characterization and genomic data
- 2019
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Ingår i: Scientific Reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 9:1
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Tidskriftsartikel (refereegranskat)abstract
- Metastatic melanoma is one of the most common deadly cancers, and robust biomarkers are still needed, e.g. to predict survival and treatment efficiency. Here, protein expression analysis of one hundred eleven melanoma lymph node metastases using high resolution mass spectrometry is coupled with in-depth histopathology analysis, clinical data and genomics profiles. This broad view of protein expression allowed to identify novel candidate protein markers that improved prediction of survival in melanoma patients. Some of the prognostic proteins have not been reported in the context of melanoma before, and few of them exhibit unexpected relationship to survival, which likely reflects the limitations of current knowledge on melanoma and shows the potential of proteomics in clinical cancer research.
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| 9. |
- Betancourt, Lazaro Hiram, et al.
(författare)
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The hidden story of heterogeneous B-raf V600E mutation quantitative protein expression in metastatic melanoma—association with clinical outcome and tumor phenotypes
- 2019
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Ingår i: Cancers. - : MDPI AG. - 2072-6694. ; 11:12
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Tidskriftsartikel (refereegranskat)abstract
- In comparison to other human cancer types, malignant melanoma exhibits the greatest amount of heterogeneity. After DNA-based detection of the BRAF V600E mutation in melanoma patients, targeted inhibitor treatment is the current recommendation. This approach, however, does not take the abundance of the therapeutic target, i.e., the B-raf V600E protein, into consideration. As shown by immunohistochemistry, the protein expression profiles of metastatic melanomas clearly reveal the existence of inter-and intra-tumor variability. Nevertheless, the technique is only semi-quantitative. To quantitate the mutant protein there is a fundamental need for more precise techniques that are aimed at defining the currently non-existent link between the levels of the target protein and subsequent drug efficacy. Using cutting-edge mass spectrometry combined with DNA and mRNA sequencing, the mutated B-raf protein within metastatic tumors was quantitated for the first time. B-raf V600E protein analysis revealed a subjacent layer of heterogeneity for mutation-positive metastatic melanomas. These were characterized into two distinct groups with different tumor morphologies, protein profiles and patient clinical outcomes. This study provides evidence that a higher level of expression in the mutated protein is associated with a more aggressive tumor progression. Our study design, comprised of surgical isolation of tumors, histopathological characterization, tissue biobanking, and protein analysis, may enable the eventual delineation of patient responders/non-responders and subsequent therapy for malignant melanoma.
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| 10. |
- Cirenajwis, Helena, et al.
(författare)
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Molecular stratification of metastatic melanoma using gene expression profiling: prediction of survival outcome and benefit from molecular targeted therapy.
- 2015
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Ingår i: Oncotarget. - : Impact Journals, LLC. - 1949-2553. ; 6:14, s. 12297-12309
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Tidskriftsartikel (refereegranskat)abstract
- Melanoma is currently divided on a genetic level according to mutational status. However, this classification does not optimally predict prognosis. In prior studies, we have defined gene expression phenotypes (high-immune, pigmentation, proliferative and normal-like), which are predictive of survival outcome as well as informative of biology. Herein, we employed a population-based metastatic melanoma cohort and external cohorts to determine the prognostic and predictive significance of the gene expression phenotypes. We performed expression profiling on 214 cutaneous melanoma tumors and found an increased risk of developing distant metastases in the pigmentation (HR, 1.9; 95% CI, 1.05-3.28; P=0.03) and proliferative (HR, 2.8; 95% CI, 1.43-5.57; P=0.003) groups as compared to the high-immune response group. Further genetic characterization of melanomas using targeted deep-sequencing revealed similar mutational patterns across these phenotypes. We also used publicly available expression profiling data from melanoma patients treated with targeted or vaccine therapy in order to determine if our signatures predicted therapeutic response. In patients receiving targeted therapy, melanomas resistant to targeted therapy were enriched in the MITF-low proliferative subtype as compared to pre-treatment biopsies (P=0.02). In summary, the melanoma gene expression phenotypes are highly predictive of survival outcome and can further help to discriminate patients responding to targeted therapy.
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