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- Frändemark, Åsa, 1988, et al.
(author)
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Fatigue: A distressing symptom for patients with irritable bowel syndrome
- 2017
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In: Neurogastroenterology and Motility. - : Wiley. - 1350-1925 .- 1365-2982. ; 29:1
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Journal article (peer-reviewed)abstract
- Background: Fatigue is a frequent symptom in patients with irritable bowel syndrome (IBS), and is associated with poor quality of life. However, few studies have evaluated its impact on daily life or the perceived distress it can cause. Using a multi-methods approach, this study describes the impact and manifestations of fatigue in patients with IBS and investigates the relationship between fatigue severity and illness-related and health-promoting factors. Methods: A total of 160 patients with IBS completed self-reported questionnaires assessing fatigue, gastrointestinal symptoms, psychological distress, and sense of coherence. Fatigue was assessed with the Fatigue Impact Scale, which also includes structured and open-ended questions which were analyzed with a deductive qualitative analysis. Patients were classified as having severe, moderate, or mild fatigue based on frequency, distress and impact on daily life. Key Results: The open-ended questions revealed a multidimensional impact on life. Fatigue mainly interfered with the ability to perform physical activities, work, and domestic work, and the ability to interact socially. Decreased stamina was evident, along with strategies to limit the bodily consequences of tiredness. Severe fatigue was accompanied by more severe IBS symptoms, anxiety and depression and lower sense of coherence. Conclusions & Inferences: Fatigue is a distressing symptom which occurs in a sizeable proportion of patients with IBS. It affects life in a multidimensional way, with poor bodily stamina being the most prominent feature. Fatigue, along with sense of coherence, depression and anxiety, needs to be assessed, confirmed and targeted for interventions.
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| 4. |
- Jakobsson, Sofie, 1968, et al.
(author)
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Patient safety before and after implementing person-centred inpatient care - A quasi-experimental study.
- 2020
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In: Journal of clinical nursing. - : Wiley. - 1365-2702 .- 0962-1067. ; 29:3-4, s. 602-612
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Journal article (peer-reviewed)abstract
- To evaluate aspects of patient safety before and after a person-centred (PC) inpatient care intervention.Transitioning from disease-centred to person-centred care requires great effort but can improve patient safety.A quasi-experimental study with data collection preceding and 12months after a PC inpatient care intervention.The study consecutively recruited adult patients (2014, n=263; 2015/2016, n=221) admitted to an inpatient care unit. The patients reported experiences of care at discharge and their perceived pain at admission and discharge. Medical records were reviewed to gather data on medications, planned care and clinical observations. The study is reported according to TREND guidelines.At discharge, patients receiving PC inpatient care reported competent medical-technical care. Patients receiving PC inpatient care reported more effective pain relief. Updated prescribed medications at the ward were maintained, and patients were made aware of planned medical care to higher extent during PC inpatient care. The assessment of pulse and body temperature was maintained, but fewer elective care patients had their blood pressure taken during PC inpatient care. Weight assessment was not prioritised during usual or PC inpatient care.Patients receiving PC inpatient care reported that they were given the best possible care and had less pain at discharge. The PC inpatient care included improved documentation and communication of planned medical care to the patients. Vital signs were more frequently recorded for patients admitted for acute care than patients admitted for elective care. PC inpatient care had no effect on frequency of weight measurements.PC inpatient care seems beneficial for the patients. Aspects of patient safety such as prescribed medications were maintained, and PC inpatient care seems to enhance the continuity of care. Inpatient clinical observations need further evaluation as healthcare transitions from disease-centred to person-centred care.
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| 5. |
- Jakobsson, Sofie, 1968, et al.
(author)
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Person-centred inpatient care - A quasi-experimental study in an internal medicine context.
- 2019
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In: Journal of advanced nursing. - : Wiley. - 1365-2648 .- 0309-2402. ; 75:8, s. 1678-1689
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Journal article (peer-reviewed)abstract
- The aim of this study was to evaluate effects of person-centred inpatient care on care processes in terms of satisfaction with care and person-centred content in medical records, and to evaluate effects on self-reported health and self-efficacy.Internal medicine inpatient care is complex, covering patients varying in age, medical conditions, health status, and other aspects. There has been limited research on the impact of person-centred care (PCC) on satisfaction with care and health outcomes in internal medicine care environments regardless of diagnosis and care pathway.A quasi-experimental study with pre- and postmeasurements.Adult patients admitted to an internal medicine inpatient unit were consecutively included over 16weeks in 2014 and 24weeks in 2015-2016. Data were collected before a person-centred inpatient care intervention (N=204) and 12months after the intervention was implemented (N=177). Data on satisfaction with care and self-reported health were collected at discharge and medical records were reviewed. The intervention included systematically applied person-centred assessment, health plans, and persistent PCC.After the intervention, patients rated higher satisfaction with care regarding essential components of PCC and more patients had received effective pain relief. There were no differences in information on self-care or medications, self-rated health, or self-efficacy.Care focused on the foundations of person-centredness seems to enhance both patients' perceptions of satisfaction and symptom management. Situational aspects such as care pathways should be considered when implementing person-centred inpatient care.CLINICALTRIALS.NCT03725813.
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| 6. |
- Adalbjörnsson, Stefan, et al.
(author)
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Conjugate priors for Gaussian emission plsa recommender systems
- 2016
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In: 2016 24th European Signal Processing Conference, EUSIPCO 2016. - 9780992862657 ; 2016-November, s. 2096-2100
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Conference paper (peer-reviewed)abstract
- Collaborative filtering for recommender systems seeks to learn and predict user preferences for a collection of items by identifying similarities between users on the basis of their past interest or interaction with the items in question. In this work, we present a conjugate prior regularized extension of Hofmann's Gaussian emission probabilistic latent semantic analysis model, able to overcome the over-fitting problem restricting the performance of the earlier formulation. Furthermore, in experiments using the EachMovie and MovieLens data sets, it is shown that the proposed regularized model achieves significantly improved prediction accuracy of user preferences as compared to the latent semantic analysis model without priors.
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| 7. |
- Adler, Jan-Olof, et al.
(author)
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The upgraded photon tagging facility at the MAX IV Laboratory
- 2013
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In: Nuclear Instruments & Methods in Physics Research. Section A: Accelerators, Spectrometers, Detectors, and Associated Equipment. - : Elsevier BV. - 0167-5087 .- 0168-9002. ; 715, s. 1-10
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Journal article (peer-reviewed)abstract
- A description is given of the upgraded photon tagging facility at the MAX IV Laboratory. Two magnetic spectrometers are used to momentum analyze post-bremsstrahlung electrons. The tagged photon range extends from 10 to 180 MeV with an energy resolution of about 300 keV. The system has been operated at rates up to 4 x 10(6) photons s(-1) MeV (-1). Different diagnostic tools are described as well as the experimental program.
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| 9. |
- Anderson, Leif G, 1951, et al.
(author)
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Shelf-Basin interaction along the East Siberian Sea
- 2017
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In: Ocean Science. - : Copernicus GmbH. - 1812-0784 .- 1812-0792. ; 13:2, s. 349-363
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Journal article (peer-reviewed)abstract
- Extensive biogeochemical transformation of organic matter takes place in the shallow continental shelf seas of Siberia. This, in combination with brine production from sea-ice formation, results in cold bottom waters with relatively high salinity and nutrient concentrations, as well as low oxygen and pH levels. Data from the SWERUS-C3 expedition with icebreaker Oden, from July to September 2014, show the distribution of such nutrient-rich, cold bottom waters along the continental margin from about 140 to 180 degrees E. The water with maximum nutrient concentration, classically named the upper halocline, is absent over the Lomonosov Ridge at 140 degrees E, while it appears in the Makarov Basin at 150 degrees E and intensifies further eastwards. At the intercept between the Mendeleev Ridge and the East Siberian continental shelf slope, the nutrient maximum is still intense, but distributed across a larger depth interval. The nutrient-rich water is found here at salinities of up to similar to 34.5, i.e. in the water classically named lower halocline. East of 170 degrees E transient tracers show significantly less ventilated waters below about 150 m water depth. This likely results from a local isolation of waters over the Chukchi Abyssal Plain as the boundary current from the west is steered away from this area by the bathymetry of the Mendeleev Ridge. The water with salinities of similar to 34.5 has high nutrients and low oxygen concentrations as well as low pH, typically indicating decay of organic matter. A deficit in nitrate relative to phosphate suggests that this process partly occurs under hypoxia. We conclude that the high nutrient water with salinity similar to 34.5 are formed on the shelf slope in the Mendeleev Ridge region from interior basin water that is trapped for enough time to attain its signature through interaction with the sediment.
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| 10. |
- Andersson, Axel G, et al.
(author)
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Large difference but high correlation between creatinine and cystatin C estimated glomerular filtration rate in Mesoamerican sugarcane cutters.
- 2022
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In: Occupational and environmental medicine. - : BMJ. - 1470-7926 .- 1351-0711. ; 79:7, s. 497-502
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Journal article (peer-reviewed)abstract
- To explore the relationship between creatinine and cystatin C based estimated glomerular filtration rate (eGFR) in actively working sugarcane cutters.This cohort study included 458 sugarcane cutters from Nicaragua and El Salvador. Serum samples were taken before and at end of harvest seasons and analysed for creatinine and cystatin C. Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) formulas were used to calculate eGFRs based on creatinine (eGFRcr), cystatin C (eGFRcys) and both creatinine and cystatin C (eGFRcrcys) at each time point. Bland-Altman plots and paired t-tests were used to compare the difference between eGFRcr and eGFRcys, and the difference in eGFRs between before and at end of the harvest seasons.The mean eGFRcr was higher than eGFRcys in both cohorts; absolute difference 22mL/min/1.73 m2 (95%CI 21 to 23) in Nicaragua and 13mL/min/1.73 m2 (95%CI 11 to 15) in El Salvador. Correlations between eGFRcr and eGFRcys were high, with r=0.69, 0.77 and 0.67 in Nicaragua at pre-harvest, end-harvest and cross-harvest, and r=0.89, 0.89 and 0.49 in El Salvador.Creatinine increases among heat-stressed workers reflect reduced glomerular filtration as estimated using eGFRcys, a marker independent of muscle mass and metabolism. The discrepancy between eGFRcr and eGFRcys may indicate reduced glomerular filtration of larger molecules and/or systemic bias in CKD-EPI performance in this population.
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