| 1. |
- Grigorenko,, et al.
(författare)
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Deep excursion beyond the proton dripline. II. Toward the limits of existence of nuclear structure
- 2018
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Ingår i: Physical Review C. - 2469-9985 .- 2469-9993. ; 98:6
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Tidskriftsartikel (refereegranskat)abstract
- Prospects of experimental studies of argon and chlorine isotopes located far beyond the proton dripline are studied by using systematics and cluster models. The deviations from the widespread systematics observed in Cl-28,Cl-29 and Ar-29,Ar-30 have been theoretically substantiated, and analogous deviations have been predicted for the lighter chlorine and argon isotopes. The limits of nuclear structure existence are predicted for Ar and Cl isotopic chains, with Ar-26 and Cl-25 found to be the lightest sufficiently long-living nuclear systems. By simultaneous measurements of protons and gamma rays following decays of such systems as well as their beta-delayed emission, an interesting synergy effect may be achieved, which is demonstrated by the example of Cl-30 and Ar-31 ground-state studies. Such a synergy effect may be provided by the new EXPERT setup (EXotic Particle Emission and Radioactivity by Tracking) being operated inside the fragment separator and spectrometer facility at GSI, Darmstadt.
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| 2. |
- Kostyleva, D., et al.
(författare)
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Towards the Limits of Existence of Nuclear Structure: Observation and First Spectroscopy of the Isotope K-31 by Measuring Its Three-Proton Decay
- 2019
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Ingår i: Physical Review Letters. - 1079-7114 .- 0031-9007. ; 123:9
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Tidskriftsartikel (refereegranskat)abstract
- The most remote isotope from the proton dripline (by 4 atomic mass units) has been observed: K-31. It is unbound with respect to three-proton (3p) emission, and its decays have been detected in flight by measuring the trajectories of all decay products using microstrip detectors. The 3p emission processes have been studied by the means of angular correlations of S-28 + 3p and the respective decay vertices. The energies of the previously unknown ground and excited states of K-31 have been determined. This provides its 3p separation energy value S-3p of -4.6(2) MeV. Upper half-life limits of 10 ps of the observed K-31 states have been derived from distributions of the measured decay vertices.
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| 3. |
- Mukha, I. G., et al.
(författare)
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Deep excursion beyond the proton dripline. I. Argon and chlorine isotope chains
- 2018
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Ingår i: Physical Review C. - 2469-9993 .- 2469-9985. ; 98:6
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Tidskriftsartikel (refereegranskat)abstract
- The proton-unbound argon and chlorine isotopes have been studied by measuring trajectories of their decay-in-flight products by using a tracking technique with microstrip detectors. The proton (1p) and two-proton (2p) emission processes have been detected in the measured angular correlations "heavy-fragment"+p and "heavy-fragment"+p+p, respectively. The ground states of the previously unknown isotopes Cl30 and Cl28 have been observed for the first time, providing the 1p-separation energies Sp of -0.48(2) and -1.60(8), MeV, respectively. The relevant systematics of 1p- and 2p-separation energies have been studied theoretically in the core+p and core+p+p cluster models. The first-time observed excited states of Ar31 allow one to infer the 2p-separation energy S2p of 6(34) keV for its ground state. The first-time observed state in Ar29 with S2p=-5.50(18) MeV can be identified as either a ground state or an excited state according to different systematics.
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| 4. |
- Mukha, I., et al.
(författare)
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Observation and Spectroscopy of New Proton-Unbound Isotopes Ar-30 and Cl-29: An Interplay of Prompt Two-Proton and Sequential Decay
- 2015
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Ingår i: Physical Review Letters. - 1079-7114 .- 0031-9007. ; 115:20, s. 7-
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Tidskriftsartikel (refereegranskat)abstract
- Previously unknown isotopes Ar-30 and Cl-29 have been identified by measurement of the trajectories of their in-flight decay products S-28 + p + p and S-28 + p, respectively. The analysis of angular correlations of the fragments provided information on decay energies and the structure of the parent states. The ground states of Ar-30 and Cl-29 were found at 2.25(-0.10)(+0.15) and 1.8 +/- 0.1 MeV above the two-and one-proton thresholds, respectively. The lowest states in Ar-30 and Cl-29 point to a violation of isobaric symmetry in the structure of these unbound nuclei. The two-proton decay has been identified in a transition region between simultaneous two-proton and sequential proton emissions from the Ar-30 ground state, which is characterized by an interplay of three-body and two-body decay mechanisms. The first hint of a fine structure of the two-proton decay of Ar-30*(2(+)) has been obtained by detecting two decay branches into the ground and first-excited states of the S-28 fragment.
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| 5. |
- Saliba-Gustafsson, P., et al.
(författare)
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Subclinical atherosclerosis and its progression are modulated by PLIN2 through a feed-forward loop between LXR and autophagy
- 2019
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Ingår i: Journal of Internal Medicine. - : Wiley. - 0954-6820 .- 1365-2796. ; 286:6, s. 660-675
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Tidskriftsartikel (refereegranskat)abstract
- Background Hyperlipidaemia is a major risk factor for cardiovascular disease, and atherosclerosis is the underlying cause of both myocardial infarction and stroke. We have previously shown that the Pro251 variant of perilipin-2 reduces plasma triglycerides and may therefore be beneficial to reduce atherosclerosis development. Objective We sought to delineate putative beneficial effects of the Pro251 variant of perlipin-2 on subclinical atherosclerosis and the mechanism by which it acts. Methods A pan-European cohort of high-risk individuals where carotid intima-media thickness has been assessed was adopted. Human primary monocyte-derived macrophages were prepared from whole blood from individuals recruited by perilipin-2 genotype or from buffy coats from the Karolinska University hospital blood central. Results The Pro251 variant of perilipin-2 is associated with decreased intima-media thickness at baseline and over 30 months of follow-up. Using human primary monocyte-derived macrophages from carriers of the beneficial Pro251 variant, we show that this variant increases autophagy activity, cholesterol efflux and a controlled inflammatory response. Through extensive mechanistic studies, we demonstrate that increase in autophagy activity is accompanied with an increase in liver-X-receptor (LXR) activity and that LXR and autophagy reciprocally activate each other in a feed-forward loop, regulated by CYP27A1 and 27OH-cholesterol. Conclusions For the first time, we show that perilipin-2 affects susceptibility to human atherosclerosis through activation of autophagy and stimulation of cholesterol efflux. We demonstrate that perilipin-2 modulates levels of the LXR ligand 27OH-cholesterol and initiates a feed-forward loop where LXR and autophagy reciprocally activate each other; the mechanism by which perilipin-2 exerts its beneficial effects on subclinical atherosclerosis.
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| 6. |
- Grigorenko, L. V., et al.
(författare)
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Complete correlation studies of two-proton decays: Be-6 and Fe-45
- 2009
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Ingår i: Physics Letters, Section B: Nuclear, Elementary Particle and High-Energy Physics. - : Elsevier BV. - 0370-2693. ; 677:1-2, s. 30-35
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Tidskriftsartikel (refereegranskat)abstract
- The complete three-body correlation pictures are experimentally reconstructed for the two-proton decays of the Be-6 and (45)e ground states. We are able to see qualitative similarities and differences between these decays. They demonstrate very good agreement with the predictions of a theoretical three-body cluster model. Validity of the theoretical methods for treatment of the three-body Coulombic decays of this class is thus established by the broad range of lifetimes and nuclear masses spanned by these cases. Implementations for decay dynamics and nuclear structure of 2p emitters are discussed. (C) 2009 Elsevier B.V. All rights reserved.
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| 7. |
- Janiak, M., et al.
(författare)
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β -delayed proton emission from P 26 and S 27
- 2017
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Ingår i: Physical Review C: covering nuclear physics. - 2469-9985. ; 95:3
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Tidskriftsartikel (refereegranskat)abstract
- Delayed emission of protons following β decay of neutron deficient nuclei P26 and S27 was investigated at the ACCULINNA separator in the Flerov Laboratory of Nuclear Reactions at Dubna. Ions of interest, identified in flight, were implanted into the active volume of the gaseous optical time projection chamber, which allowed us to record tracks of charged particles emitted in the decay. Total branching ratios for β-delayed proton emission and for β-delayed two-proton emission were determined. In addition, energy spectra for delayed protons below 2 MeV were established. Our findings for P26 agree with results of previous experiments. In the case of S27, however, the observed probability of delayed proton emission is an order of magnitude larger than reported in literature. Two new strong proton transitions were identified representing decays of the first two excited states of P27 to the ground state of Si26. The probability ratio of γ-to-proton emission from these states is discussed.
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| 8. |
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