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| 2. |
- Jansson, Jenny, 1979-, et al.
(författare)
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Borderland Stories : Life at the Russian Border
- 2014
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Ingår i: Tractus Aevorum. - Belgorod : Belgorod National Research University. - 2312-3044. ; 1:2, s. 234-238
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- This paper details the project ―Borderland Stories,‖ which focuses on national identity in various borderland regions of the Russian Federation. The authors point out that the contradiction between the pronunciation of national identity in the borderlands and the practical aspects of borders makes it particularly exciting to focus on national identity formation and daily life in the borderlands, especially in a huge country, such as the Russian Federation, that borders many different countries. Collection and analysis of the material are being conducted in 2014 and the first results are due for presentation in 2015.
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| 3. |
- Jansson, Jenny, 1979-, et al.
(författare)
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Technological Shifts and the Social Partners : Is the European Semester Heading Towards a Social Europe?
- 2021. - 1
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Ingår i: The European Union and the Technology Shift. - London : Palgrave Macmillan. - 9783030636722 ; , s. 161-183
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Bokkapitel (refereegranskat)abstract
- This chapter describes and analyses the involvement of trade unions and employers’ organisations in the European Semester (ES) in EU member states. The ES is an important governance mechanism available to the EU to guide economic development in light of an imminent technological shift and, at the same time, involves organisations representing both workers and employers. The analysis shows that the ES could work as a bridge between growth and social reforms where the social partners are involved to ensure that all interests are considered in the governance of EU economic policy. However, the chapter also shows that there are substantive differences among the EU member states as to the extent to which if and when the social partners have a say, when they are involved in the process and whether governments listen to the social partners.
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| 7. |
- Jansson, Olle, 1978-, et al.
(författare)
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Neither sticks nor carrots: Swedish trade union involvement in the European Semester : Case study Sweden
- 2019
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- The aim of this OSE Research paper is to ascertain to what extent the social partners in Sweden are involved in the different stages of the European Semester: what do they expect (if anything) to gain from this involvement, and do they perceive that they have an influence on the outputs and outcomes of the process? By studying available written documents and conducting interviews with representatives of the trade union confederations, employer organizations and civil servants from the government’s office, we have reconstructed the involvement of the national-level social partners in the European Semester. The Swedish case is characterized by a strong institutional framework for national social dialogue as well as weak EU pressure to adapt to the European Union’s (EU) Country-specific Recommendations (CSR) or other policy recommendations emanating from the Semester. Sweden is not part of the Eurozone and the economic recovery after the great recession has been comparatively good. In terms of the geographical typology for industrial relations used in the INVOTUNES project, Sweden is one of the ‘Northern countries’, together with Denmark, Finland and Norway. Fundamental components of the Swedish model for industrial relations, together with the high unionisation rate and broad membership, are the strong status of collective agreements, workplace representatives with a mandate to negotiate, as well as the independence of the social partners from central government. The labour market is regulated by a number of principal agreements reached at the central level between employers’ organizations and trade unions. These central agreements regulate aspects including negotiation procedures, dispute procedures and development issues. In contrast to many other countries, there are no state-administered minimum wage levels in Sweden, since the social partners negotiate these key aspects. The political situation in Sweden at the time of writing is characterised by a minority government, composed of the Social Democrats and the Green party, supported by the Liberals and the Centre party (two liberal parties). The Swedish case illustrates how a strong national social dialogue and low degree of EU pressure mean that, on the one hand, the social partners have moderate to good access to the policy process and possess considerable resources which can be used to impact the European Semester. Regardless, they ultimately have limited incentives to use these tools to influence the outputs and outcomes of the policy process. So far, the outputs from the European Semester have not pushed for concrete reforms in the areas for which the social partners are mainly responsible, thus they have had few reasons to be involved in the process. Moreover, as the national social dialogue functions well, they have no interest in using the Commission to put pressure on the national government. Instead, the social partners wish to raise the awareness of the European Commission and others regarding how industrial relations function in Sweden and how beneficial this model is. The long-term goal of the social partners is to preserve their autonomy and the model of wage formation in Sweden, namely the freedom of the social partners to reach agreements through negotiations. Reaching this goal includes protecting the wage formation model from reforms at European level. Therefore, this study suggests that the social partners monitor the work related to the Semester and take action if the CSRs concern issues that are important to them. So far this has rarely been the case. When the social partners choose to become involved in the Semester, they use insider strategies, i.e. they turn to national rather than European-level actors. The Swedish government has created formal institutions for ensuring the involvement of the social partners in the Semester work. The partners have meetings with the government regularly during the Semester, while unions and employer organizations together write an annex to the National Reform Programme (NRP). For Sweden, the policy recommendations for meaningful involvement would probably call for a more focused dialogue between local and central levels within the social partner organisations. In trying to strengthen positive incentives for such dialogue, the unions would most likely need to involve the various members more actively than they do today.
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| 8. |
- Adrian Meredith, Jenny, 1971-, et al.
(författare)
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Design and Synthesis of BACE-1 Inhibitors Containing a New Hydroxyethylene (HE) Scaffold: Potent activities in a cellular assay
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Annan publikation (övrigt vetenskapligt/konstnärligt)abstract
- In a preceding report from our group we disclosed the development of a novel HE transition state isostere with a difluorophenoxymethyl side chain in the P1 position and a methoxy group in the P1’ position furnishing highly potent inhibitors of BACE-1 (i.e. lead compound 1), which moreover exhibit very promising selectivity over cathepsin D. In a continuation of this work with the aim at improving on the cell-based activity and pharmacokinetic properties, we have further developed the SAR for the P1 side chain of inhibitor 1 whereby the P1 side chain oxygen has been substituted for an amine, a carbon or a bond. The chemistry developed for the previous HE inhibitor structure 1 has now been extended to readily accommodate the introduction of new P1 side chains into this new HE scaffold. These modifications have given rise to several highly potent inhibitors where the most potent displayed a BACE-1 Ki value of 0.2 nM and a cell-based Aβ40 IC50 value of 9 nM. Thus, regarding the enzyme inhibition in the cell assay a more than 600-fold improvement compared to compound 1 was achieved via minor structural alterations.
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| 9. |
- Adrian Meredith, Jenny, 1971-, et al.
(författare)
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P2 '-truncated BACE-1 inhibitors with a novel hydroxethylene-like core
- 2010
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Ingår i: European Journal of Medicinal Chemistry. - : Elsevier BV. - 0223-5234 .- 1768-3254. ; 45:2, s. 542-554
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Tidskriftsartikel (refereegranskat)abstract
- Highly potent BACE-1 protease inhibitors derived from a novel hydroxyethylene-like core structure were recently developed by our group using X-ray crystal structure data and molecular modelling. In a continuation of this work guided by molecular modelling we have explored a truncated core motif where the P2' amide group is replaced by an ether linkage resulting in a set of alkoxy, aryloxy and alkylaryl groups, with the overall aim to reduce molecular weight and the number of amide bonds to increase permeability and bestow the inhibitors with drug-like features. The most potent of these inhibitors displayed a BACE-I IC50 value of 140 nM. The synthesis of these BACE-I inhibitors utilizes readily available starting materials, furnishing the target compounds in good overall yields.
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| 10. |
- Andersson, Hanna, et al.
(författare)
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Natur på skolgården för lärande, hälsa och hållbarhet
- 2024. - 2024
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Rapport (populärvet., debatt m.m.)abstract
- Gröna och artrika utemiljöer främjar barns och ungas välbefinnande och kunskap, bådegenom hälsofördelar kopplade till biologisk mångfald och genom att skapa förutsättningarför lek och lärande om natur och miljöfrågor. Skolgården skulle kunna bidra till allt detta,men är idag i hög grad en outnyttjad plats för biologisk mångfald och klimatanpassningav städer. I denna policy brief presenteras huvudsakliga motiv och möjliga åtgärder för attutveckla gröna miljöer och biologisk mångfald på skolgårdar och förskolegårdar.
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