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- Bousquet, J., et al.
(författare)
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Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5)
- 2016
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Ingår i: Clinical and Translational Allergy. - : Wiley. - 2045-7022. ; 6:1, s. 1-18
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Forskningsöversikt (refereegranskat)abstract
- Action Plan B3 of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) focuses on the integrated care of chronic diseases. Area 5 (Care Pathways) was initiated using chronic respiratory diseases as a model. The chronic respiratory disease action plan includes (1) AIRWAYS integrated care pathways (ICPs), (2) the joint initiative between the Reference site MACVIA-LR (Contre les MAladies Chroniques pour un VIeillissement Actif) and ARIA (Allergic Rhinitis and its Impact on Asthma), (3) Commitments for Action to the European Innovation Partnership on Active and Healthy Ageing and the AIRWAYS ICPs network. It is deployed in collaboration with the World Health Organization Global Alliance against Chronic Respiratory Diseases (GARD). The European Innovation Partnership on Active and Healthy Ageing has proposed a 5-step framework for developing an individual scaling up strategy: (1) what to scale up: (1-a) databases of good practices, (1-b) assessment of viability of the scaling up of good practices, (1-c) classification of good practices for local replication and (2) how to scale up: (2-a) facilitating partnerships for scaling up, (2-b) implementation of key success factors and lessons learnt, including emerging technologies for individualised and predictive medicine. This strategy has already been applied to the chronic respiratory disease action plan of the European Innovation Partnership on Active and Healthy Ageing.
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- Cassia-Silva, C., et al.
(författare)
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Acaulescence promotes speciation and shapes the distribution patterns of palms in Neotropical seasonally dry habitats
- 2022
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Ingår i: Ecography. - : Wiley. - 0906-7590 .- 1600-0587. ; 3
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Tidskriftsartikel (refereegranskat)abstract
- Rainforests have been a source of lineages to open and seasonally dry habitats throughout Angiosperm evolution, especially in the Neotropics. However, the underlying mechanisms that allow such shifts remain poorly understood at large spatial scales. Here, we test whether acaulescence (an underground stem or a very short stem concealed in the ground) has affected the colonization and speciation in Neotropical seasonally dry habitats by cocosoid palms (Cocoseae). Acaulescent species maintain their growth underground, which increases their chances of survival from prolonged seasonal dry season and frequent fires. We use an integrative approach based on trait-dependent diversification models, phylogenetic comparative methods and ecological niche models. We found that shifts towards acaulescent growth form were accompanied by evolutionary transitions to seasonally dry habitats. Acaulescent lineages had higher speciation rates than non-acaulescent ones. However, the interaction between acaulescence and seasonally dry habitats had no significant effect on Cocoseae speciation rates. Acaulescent palms are primarily distributed in Neotropical seasonally dry habitats and non-acaulescent palms are concentrated in Amazonian rainforests. Our results suggest that an underground stem, with high carbohydrate and water storage capacity, is a preadaptation by which rainforest lineages were able to colonize and diversify in new fire-prone, increasingly seasonal and drier adaptive zones. The projected global expansion of dry seasonal habitats requires an understanding of how drought-avoidance functional traits evolve and how they are linked to seasonally dry habitats. Our results are, thus, a step forward in determining plant response mechanisms to drier and seasonal conditions.
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