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- Abd Nikooie Pour, Mina, et al.
(author)
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Results of the Ontology Alignment Evaluation Initiative 2021
- 2021
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In: Proceedings of the 16th International Workshop on Ontology Matching co-located with the 20th International Semantic Web Conference (ISWC 2021), Virtual conference, October 25, 2021. - : CEUR-WS.org. ; , s. 62-108, s. 62-108
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Conference paper (peer-reviewed)abstract
- The Ontology Alignment Evaluation Initiative (OAEI) aims at comparing ontology matching systems on precisely defined test cases. These test cases can be based on ontologies of different levels of complexity and use different evaluation modalities (e.g., blind evaluation, open evaluation, or consensus).The OAEI 2021 campaign offered 13 tracks and was attended by 21 participants.This paper is an overall presentation of that campaign.
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- Abd Nikooie Pour, Mina, et al.
(author)
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Results of the Ontology Alignment Evaluation Initiative 2023
- 2023
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In: Proceedings of the 18th International Workshop on Ontology Matching co-located with the 22nd International Semantic Web Conference (ISWC 2023), Athens, Greece, November 7, 2023.. - : CEUR Workshop Proceedings. ; , s. 97-139
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Conference paper (peer-reviewed)
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- Blake, Jessie A, et al.
(author)
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Design of xanthone propionate photolabile protecting group releasing acyclovir for the treatment of ocular herpes simplex virus
- 2012
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In: Photochemical and Photobiological Sciences. - : Royal Society of Chemistry. - 1474-905X .- 1474-9092. ; 11:3, s. 539-547
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Journal article (peer-reviewed)abstract
- We have attached the antiviral drug acyclovir (ACV) to a xanthone photolabile protecting group (or photocage) through the O6 position of acyclovir, a procedure designed for the treatment of ocular herpes simplex virus infections. Acyclovir is photoreleased from the photocage, under physiological conditions, with a quantum yield (Phi(ACV release)) of 0.1-0.3 and an uncaging cross section (Phi.epsilon) of 450-1350 M cm(-1). We demonstrate that this photorelease method outcompetes alternative reaction pathways, such as protonation. Furthermore, complete release of the drug is theoretically possible given a sufficient dose of light. Surprisingly the acyclovir photocage, also showed some antiviral activity towards HSV-1.
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