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- Johanson, Cecilia N, et al.
(författare)
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Prevalence and incidence of dental caries and related risk factors in 70- to 76-year-olds.
- 2009
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Ingår i: Acta odontologica Scandinavica. - : Informa UK Limited. - 1502-3850 .- 0001-6357. ; , s. 1-9
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Tidskriftsartikel (refereegranskat)abstract
- Objective. The prevalence of caries and various risk factors was studied cross-sectionally in two cohorts of 72-year-olds over the course of 20 years. Incidence was also studied over a period of 6 years. Material and Methods. Samples of two dentate subjects from cohorts of 70 to 72-year-olds were included; cohort III (n=135), born 1911-12, and cohort VI (n=139), born 1930. Cohort III was also examined at 70 years of age and re-examined after 6 years. An interview and clinical examination, including DMFS, plaque and gingival bleeding indices, pocket depth, and secretion rate for stimulated whole saliva, were carried out. Results. The mean numbers of teeth in cohorts III and VI were 14 and 21, respectively. On average, 2.1 tooth surfaces were decayed (DS) in cohort III compared with 1.3 in cohort VI (p<0.05). 49% of the individuals in cohort III did not develop any new DS, while 19% developed >/=3 DS during the 6-year follow-up period. The prevalence of caries was related to plaque and gingival bleeding indices, as well as a pocket depth of >/=4 mm, at ages 70 and 72. Moreover, the incidence of caries was related to the same factors. Conclusions. The numbers of remaining teeth increased and the prevalence of caries decreased over the 20-year period. The incidence of caries over the follow-up period of 6 years was moderate. The results indicate that the prevalence of plaque, gingival bleeding, and a pocket depth of >/=4 mm are predictive factors for both prevalence and incidence of caries.
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| 2. |
- Johanson, Cecilia N, et al.
(författare)
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Salivary secretion and drug treatment in four 70-year-old Swedish cohorts during a period of 30 years
- 2015
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Ingår i: Gerodontology. - : Wiley. - 0734-0664. ; 32:3, s. 202-210
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Tidskriftsartikel (refereegranskat)abstract
- Objective The aim was to examine the association between drug treatment and unstimulated and stimulated whole saliva in four 70-year-old Swedish cohorts, between 1971 and 2001. Background Both diseases and their medication can affect the salivary secretion rate. Materials and methods The study was based on selected samples of four cohorts born in 1901/1902, 1906/1907, 1911/1912 and 1930/1931, respectively, a total of 1072 individuals. The response rate varied between 65% and 85%. Results The mean value for the stimulated salivary secretion rate was higher in men (1.30.8ml/min) than in women (1.0 +/- 0.7ml/min) (p<0.001)). There was a significant association between the salivary secretion rate and the number of drugs among both women (p<0.01) and men (p<0.001). This influence was most pronounced in participants who were treated with cardiovascular drugs, mainly diuretics and non-selective -adrenoceptor blockers, but also with antipsychotics and antidepressants, even when adjusted for cohort, gender, number of teeth and other drugs. There was an increase in treatment with medicines during the three decades. Conclusion In these four groups of 70-year-old participants, high drug consumption was associated with lower salivary flow. Unstimulated secretion was only affected in women and then, when taking four or more drugs. Pronounced hyposalivation was, however, uncommon. Cardiovascular drugs, antidepressants and antipsychotics were associated with low salivary secretion. In this age group, the frequently observed association between polypharmacy and a lower saliva secretion rate represents a risk of impaired dental health.
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