| 1. |
- Andréen, David, et al.
(författare)
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Biodigital Futures
- 2021
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Konstnärligt arbete (refereegranskat)abstract
- The exhibition Biodigital Futures is part of the Venice Biennale collateral event Time Space Existence. It explores the future of 3d printing technology in architecture through two full scale prototypes: Meristem Wall and Protomycokion.
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| 2. |
- Goidea, Ana, et al.
(författare)
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Algorithmic modeling of functionally graded metamaterials in 3D printed building envelopes
- 2024
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Ingår i: Architectural Intelligence. - 2731-6726. ; 3
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Tidskriftsartikel (refereegranskat)abstract
- Recent development of powder-bed additive manufacturing promises to enable the production of architectural structures that combine high resolution and articulation with economies of scale. These capabilities can potentially be used for functionally graded metamaterials as part of the building envelope and structure, paving the way for new functionalities and performances. However, designing such multifunctional structures requires new design and modelling strategies to control, understand, and generate complex geometries and their transcalar interdependencies. The work presented here demonstrates a modeling framework that can unite multiple generative and organizational algorithms to create a unified, 3D printable building element that integrates a range of functional requirements. Our methods are based on an understanding of stigmergic principles for self-organization and developed to allow for a wide range of application scenarios and design intents. The framework is structured around a composite modeling environment based on a combination of volumetric modeling and particle-spring systems, and is developed to negotiate the large scalar range necessary for such applications. We present here a prototype demonstrator designed using this framework: Meristem Wall, a functionally integrated building envelope fabricated through a combination of powder bed 3D printing and CNC knitting.
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| 3. |
- Hellman, Jan, et al.
(författare)
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Mechanisms of increased methane production through re-circulation of magnetic biomass carriers in an experimental continuously stirred tank reactor
- 2010
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Konferensbidrag (refereegranskat)abstract
- Magnetite particles were used in a semi-continuous process as magnetic biomass carriers to separate and re-introduce microorganisms in a CSTR reactor. In comparison to a control reactor the methane content during the semi-continuous process was elevated when magnetite particles were used. The difference was most apparent during the fermentative step directly after feeding and upon direct spiking with volatile fatty acids. Total DNA quantification of the separated magnetite particles revealed high association of microorganisms. Furthermore, quantitative real-time PCR analysis of the associated microbial consortia indicated that the hydrogenotrophic Methanobacteriales was overrepresented at the particle surface. Thus, the increased methane production could be coupled to both the crowding and shorter interspecies distances between the groups involved in anaerobic digestion, as well as a preferential adsorption of hydrogenotrophs. By bringing the hydrogenotrophs closer to the primary fermentative bacteria and increasing their relative number the produced hydrogen during acidogenesis is more effectively utilized and more carbon dioxide is converted to methane. Furthermore, by the same cause, the rate of acetogenesis increased as the hydrogenotrophs more effectively could consume the hydrogen produced and thereby keep the hydrogen partial pressure low.
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| 4. |
- Jalo, Noor, et al.
(författare)
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Barriers to and drivers of energy management in Swedish SMEs
- 2021
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Ingår i: Energies. - : MDPI. - 1996-1073. ; 14:21
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Tidskriftsartikel (refereegranskat)abstract
- The energy efficiency gap is known as the difference between optimal level of energy efficiency and the actual level of achieved energy efficiency. Energy management has proven to further close the energy efficiency gap. Energy management may differ depending on whether it concerns a large, energy-intensive company or small and medium-sized enterprises (SMEs). SMEs are of high interest since they form a large share of the economy today. For SMEs, a lighter form of energy management, in the form of energy efficiency network participation, has proven to deliver sound energy efficiency impact, while for larger, energy-intensive firms, a certified energy management system may be more suitable. However, various barriers inhibit adoption of energy efficiency measures. While there is an array of research on barriers to and driving forces for energy efficiency in general, research on barriers to, and driving forces for, energy management is rare, one exception being a study of energy-intensive pulp and paper mills. This holds even more so for industrial SMEs. This paper aims to identify the barriers to, and drivers for, energy management in manufacturing SMEs. Results of this explorative study show that the top four barriers to energy management are lack of time/other priorities, non-energy-related working tasks are prioritized higher, slim organization, and lack of internal expert competences, i.e., mainly organizational barriers. The top four drivers for energy management are to reduce production waste, participation in energy efficiency networks, cost reduction from lower energy use, and commitment from top management. Furthermore, results show that energy management among the studied SMEs seems to not be as mature, even though the companies participated in an energy management capacity building program in the form of energy efficiency networks, which, in turn, shows a still largely untapped potential in the societal aim to reduce the energy efficiency and management gaps. The main contribution of this paper is a first novel attempt to explore barriers to, and drivers for, energy management among SMEs.
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| 7. |
- Nordell, Erik, et al.
(författare)
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The Diverse Response on Degradation Rate of Different Substrates Upon Addition of Zeolites
- 2010
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Ingår i: 3rd International Symposium on Energy from Biomass and Waste. Venice, Italy, Nov 8-11, 2010..
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Konferensbidrag (refereegranskat)abstract
- SUMMARY: This study evaluates the effects of addition of the natural zeolite clinoptilolite to anaerobic digesters treating different materials in both batch and continuous lab-scale setups. Zeolite addition to a CSTR with high ammonium levels (5 g NH4+/L) was performed with the purpose to investigate the effects on the amount of free ammonium. We also investigated non ammonium related effects of zeolite addition in dosage between 0-10 g zeolite/L to distinguish any beneficial properties effects. The concentration that was found to be most suitable for slaughterhouse waste (5 g zeolite/L) was subsequently tested and compared in batch conditions for slaughterhouse waste, thin stillage from ethanol production and sewage sludge. Batch experiments with slaughterhouse waste with 5 g zeolite/L significantly decreased the lag phase and in effect increased the degradation rate; no similar effect could be identified for the other substrates tested. We suggest that the increase of degradation rate when adding zeolites in low concentrations is unrelated to the ammonium reduction caused by the zeolite.
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| 8. |
- Van De Munckhof, Anita, et al.
(författare)
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Outcomes of cerebral venous thrombosis due to vaccine-induced immune thrombotic thrombocytopenia after the acute phase
- 2022
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Ingår i: Stroke. - : American Heart Association. - 0039-2499 .- 1524-4628. ; 53:10, s. 3206-3210
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Tidskriftsartikel (refereegranskat)abstract
- Background: Cerebral venous thrombosis (CVT) due to vaccine-induced immune thrombotic thrombocytopenia (VITT) is a severe condition, with high in-hospital mortality rates. Here, we report clinical outcomes of patients with CVT-VITT after SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) vaccination who survived initial hospitalization.Methods: We used data from an international registry of patients who developed CVT within 28 days of SARS-CoV-2 vaccination, collected until February 10, 2022. VITT diagnosis was classified based on the Pavord criteria. Outcomes were mortality, functional independence (modified Rankin Scale score 0-2), VITT relapse, new thrombosis, and bleeding events (all after discharge from initial hospitalization).Results: Of 107 CVT-VITT cases, 43 (40%) died during initial hospitalization. Of the remaining 64 patients, follow-up data were available for 60 (94%) patients (37 definite VITT, 9 probable VITT, and 14 possible VITT). Median age was 40 years and 45/60 (75%) patients were women. Median follow-up time was 150 days (interquartile range, 94-194). Two patients died during follow-up (3% [95% CI, 1%-11%). Functional independence was achieved by 53/60 (88% [95% CI, 78%-94%]) patients. No new venous or arterial thrombotic events were reported. One patient developed a major bleeding during follow-up (fatal intracerebral bleed).Conclusions: In contrast to the high mortality of CVT-VITT in the acute phase, mortality among patients who survived the initial hospitalization was low, new thrombotic events did not occur, and bleeding events were rare. Approximately 9 out of 10 CVT-VITT patients who survived the acute phase were functionally independent at follow-up.
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| 9. |
- Wang, Zhaoming, et al.
(författare)
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Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33
- 2014
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Ingår i: Human Molecular Genetics. - : Oxford University Press (OUP). - 0964-6906 .- 1460-2083. ; 23:24, s. 6616-6633
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Tidskriftsartikel (refereegranskat)abstract
- Genome-wide association studies (GWAS) have mapped risk alleles for at least 10 distinct cancers to a small region of 63 000 bp on chromosome 5p15.33. This region harbors the TERT and CLPTM1L genes; the former encodes the catalytic subunit of telomerase reverse transcriptase and the latter may play a role in apoptosis. To investigate further the genetic architecture of common susceptibility alleles in this region, we conducted an agnostic subset-based meta-analysis (association analysis based on subsets) across six distinct cancers in 34 248 cases and 45 036 controls. Based on sequential conditional analysis, we identified as many as six independent risk loci marked by common single-nucleotide polymorphisms: five in the TERT gene (Region 1: rs7726159, P = 2.10 × 10(-39); Region 3: rs2853677, P = 3.30 × 10(-36) and PConditional = 2.36 × 10(-8); Region 4: rs2736098, P = 3.87 × 10(-12) and PConditional = 5.19 × 10(-6), Region 5: rs13172201, P = 0.041 and PConditional = 2.04 × 10(-6); and Region 6: rs10069690, P = 7.49 × 10(-15) and PConditional = 5.35 × 10(-7)) and one in the neighboring CLPTM1L gene (Region 2: rs451360; P = 1.90 × 10(-18) and PConditional = 7.06 × 10(-16)). Between three and five cancers mapped to each independent locus with both risk-enhancing and protective effects. Allele-specific effects on DNA methylation were seen for a subset of risk loci, indicating that methylation and subsequent effects on gene expression may contribute to the biology of risk variants on 5p15.33. Our results provide strong support for extensive pleiotropy across this region of 5p15.33, to an extent not previously observed in other cancer susceptibility loci.
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