1. |
- Jonsson, Herbert, 1962-, et al.
(författare)
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Kaneko Tōta : En röst i dimman
- 2019
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Bok (populärvet., debatt m.m.)abstract
- Den japanske haikudiktaren Kaneko Tōta (1919-2018) var en av nittonhundratalets mest inflytelserika lyriker. Han tillhörde den grupp av diktare som vände sig bort från traditionella uttryckssätt och experimenterade med både politiska teman och avantgardism. Ett urval av hans haiku har här för första gången tolkats till svenska. De introduceras med en kort biografisk bakgrund och ett antal reflektioner kring hur hans dikter kan läsas med behållning.
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2. |
- Beal, Jacob, et al.
(författare)
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Robust estimation of bacterial cell count from optical density
- 2020
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Ingår i: Communications Biology. - : Springer Science and Business Media LLC. - 2399-3642. ; 3:1
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Tidskriftsartikel (refereegranskat)abstract
- Optical density (OD) is widely used to estimate the density of cells in liquid culture, but cannot be compared between instruments without a standardized calibration protocol and is challenging to relate to actual cell count. We address this with an interlaboratory study comparing three simple, low-cost, and highly accessible OD calibration protocols across 244 laboratories, applied to eight strains of constitutive GFP-expressing E. coli. Based on our results, we recommend calibrating OD to estimated cell count using serial dilution of silica microspheres, which produces highly precise calibration (95.5% of residuals <1.2-fold), is easily assessed for quality control, also assesses instrument effective linear range, and can be combined with fluorescence calibration to obtain units of Molecules of Equivalent Fluorescein (MEFL) per cell, allowing direct comparison and data fusion with flow cytometry measurements: in our study, fluorescence per cell measurements showed only a 1.07-fold mean difference between plate reader and flow cytometry data.
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3. |
- Behrendt Jonsson, Britta, 1973-
(författare)
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The Solvency II Capital Requirement for Insurance Groups : On the Tension Between Regulatory Law and Company Law
- 2018
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Since 2016, supervision of insurance undertakings in the European Union has been based on the Solvency II legal Since 2016, supervision of insurance undertakings in the European Union has been based on the Solvency II legal framework. Insurance undertakings that are part of an insurance group must be sufficiently capitalized both at company level and at group level. For the calculation of the group solvency capital requirement, insurance groups are regarded as if they were a single economic entity, whereas company and insolvency law apply a legal entity perspective and focus on each single company that is part of a group. The underlying expectation that excess own funds within a group will be used to support a group undertaking in financial difficulties is not reflected by a corresponding legal obligation.This tension between regulatory and company law is discussed in the thesis. The rules on the calculation of the group solvency requirement and the eligibility of own funds at group level are analyzed against the background of German and Swedish company law and possible solutions to align the two areas of law are discussed de lege lata and de lege ferenda. Despite the full harmonization approach of the Solvency II Directive and the aim of reaching supervisory convergence throughout the EU, the study reveals differences in the application of Solvency II in Germany and Sweden.
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4. |
- Bos, Herbert, et al.
(författare)
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Anticipating Security Threats to a Future Internet
- 2009
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Ingår i: EU/FP7 FORWARD.
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- One of the most critical problems on today’s Internet is the lack of security. This gives rise to aplethora of different ways in which the confidentiality, integrity, and availability of data is compromised,and it provides a fertile breeding ground for a thriving underground economy. Thus, when designing afuture Internet, it is clear that security must be a first-class design consideration.To be able to design security for a future Internet, it is first necessary to obtain a thorough understandingof the threats and adversaries that the system must defend against. As a first step toward thisunderstanding, we introduce a number of emerging security threats that need to be considered. Thesethreats were identified by the three working groups that are active in the context of the EU FP7 projectFORWARD, and they illuminate different aspects of the threat landscape.
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5. |
- Bos, Herbert, et al.
(författare)
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Future threats to future trust
- 2008
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Ingår i: Future of Trust in Computing: Proceedings of the First International Conference Future of Trust in Computing 2008: With 58 Illustrations. - Wiesbaden : Vieweg+Teubner. - 9783834807946 ; , s. 49-54
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- Only a few years ago, big worms roamed theplanet, spreading within hours, or even minutes, toevery nook and cranny of the Internet. The damagecaused by them was equally impressive; wormshave taken out alarm phone centers, train signallingsystems, thousands of cash machines, millions ofproduction PCs and servers, and, oh yes, SouthKorea1.No wonder academics and industry scrambledto counter the threat. Indeed, fast spreading flashworms were all the rage among security expertsand millions of euros were spent on projects tocounter them. Alliances were formed, researchgrants applied for, projects started, prototype solutionsdeveloped, refined, and discarded. Unfortunately,by the time we developed practical countermeasures, flash worms had all but disappeared.Instead, we now worry about stealth attacks, botnets,phishing sites, attacks on mobile phones, andwhatever new threats emerged in recent years. Theproblem is that we tend to work on solutions fortoday’s problems and have no time to worry aboutthe threats of the future. The problem is that weare often caught unawares.This need not be the case and there are examplesof threats that we saw coming before they hit us.A well-known example is RFID. An RFID tagis a small, extremely low-cost chip that can beused for purposes like identification and minimalprocessing. By adding RFID tags to everything,from pets to products, industry aims to use RFIDtechnology to create the “Internet of Things”. However,researchers have shown that tags can be usedto propagate malware, which in turn has led aconcerned industry to scrutinize security issues inRFID. All of this happened before any real attackstook place.For this reason the FORWARD initiative intendsto bring together experts to discuss future threatsand develop realistic threat scenarios. As a firststep in that direction, a workshop was organized1The country virtually dropped off the map as a result of theSlammer worm [2].in G¨oteborg, Sweden, in April 2008, to discussfuture threats [1]. The workshop consisted of broadplenary sessions interspersed with focused expertsmeetings. This paper summarizes the workshop’sfindings and their bearings on the future of trust.The remainder of this paper discusses the findingsof the targeted expert meetings on criticalinfrastructure and large scale systems (Section II),fraud (Section III), and malware (Section IV).Concluding remarks are in Section V.
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6. |
- Bridel, Claire, et al.
(författare)
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Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology : A Systematic Review and Meta-analysis
- 2019
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Ingår i: JAMA Neurology. - : American Medical Association (AMA). - 2168-6149 .- 2168-6157. ; 76:9, s. 1035-1048
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Forskningsöversikt (refereegranskat)abstract
- Importance Neurofilament light protein (NfL) is elevated in cerebrospinal fluid (CSF) of a number of neurological conditions compared with healthy controls (HC) and is a candidate biomarker for neuroaxonal damage. The influence of age and sex is largely unknown, and levels across neurological disorders have not been compared systematically to date.Objectives To assess the associations of age, sex, and diagnosis with NfL in CSF (cNfL) and to evaluate its potential in discriminating clinically similar conditions.Data Sources PubMed was searched for studies published between January 1, 2006, and January 1, 2016, reporting cNfL levels (using the search terms neurofilament light and cerebrospinal fluid) in neurological or psychiatric conditions and/or in HC.Study Selection Studies reporting NfL levels measured in lumbar CSF using a commercially available immunoassay, as well as age and sex.Data Extraction and Synthesis Individual-level data were requested from study authors. Generalized linear mixed-effects models were used to estimate the fixed effects of age, sex, and diagnosis on log-transformed NfL levels, with cohort of origin modeled as a random intercept.Main Outcome and Measure The cNfL levels adjusted for age and sex across diagnoses.Results Data were collected for 10 059 individuals (mean [SD] age, 59.7 [18.8] years; 54.1% female). Thirty-five diagnoses were identified, including inflammatory diseases of the central nervous system (n = 2795), dementias and predementia stages (n = 4284), parkinsonian disorders (n = 984), and HC (n = 1332). The cNfL was elevated compared with HC in a majority of neurological conditions studied. Highest levels were observed in cognitively impaired HIV-positive individuals (iHIV), amyotrophic lateral sclerosis, frontotemporal dementia (FTD), and Huntington disease. In 33.3% of diagnoses, including HC, multiple sclerosis, Alzheimer disease (AD), and Parkinson disease (PD), cNfL was higher in men than women. The cNfL increased with age in HC and a majority of neurological conditions, although the association was strongest in HC. The cNfL overlapped in most clinically similar diagnoses except for FTD and iHIV, which segregated from other dementias, and PD, which segregated from atypical parkinsonian syndromes.Conclusions and Relevance These data support the use of cNfL as a biomarker of neuroaxonal damage and indicate that age-specific and sex-specific (and in some cases disease-specific) reference values may be needed. The cNfL has potential to assist the differentiation of FTD from AD and PD from atypical parkinsonian syndromes.
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7. |
- Edelbro, Catrin, et al.
(författare)
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European initiative on CDIO in raw material programmes
- 2017
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Ingår i: Proceedings of the 13th International CDIO Conference in Calgary. - Calgary.
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Konferensbidrag (refereegranskat)abstract
- One of five Knowledge and Innovation Communities (KICs), was launched in Europe in 2014and has its focus on exploration, extraction, mineral processing, metallurgy, recycling andmaterial substitution of raw materials. To reach the vision, where the European Union’sindustrial strength is based on a cost-efficient, secure, sustainable supply and use of rawmaterials, a new generation of skilled people entering industry, universities and researchneeds to be developed. Today’s technical MSc graduates in raw materials and especiallyprimary resources (i.e. exploration, extraction, mining and mineral processing and metallurgy)best suits large companies where they often act as specialists and experts. For small tomedium enterprises as well as for our future engineers other skills than technical arenecessary. As a part of the KIC Raw Materials, the education project “The implementation ofCDIO in raw material programmes” started in 2016. The project focuses, during 2016-2017,on (WP1) faculty- and (WP2) pilot case development. There are no academic institutes inEurope that have yet applied CDIO for primary resource related MSc programmes. Thispaper describes an education project within the KIC Raw material and presents key outputswith implementing CDIO in mining and metallurgy related programmes.
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8. |
- Gilsenan Nordin, Irene, et al.
(författare)
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Introduction: Transcultural Identity Constructions in a Changing World
- 2016
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Ingår i: Transcultural Identity Constructions in a Changing World. - Frankfurt am Main : Peter Lang Publishing Group. - 9783631660614 - 9783653054156 ; , s. 11-20
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Bokkapitel (refereegranskat)abstract
- Although the phenomenon of transculturality has existed as long as human culture, the increased speed of movement and communication worldwide has made it impossible to ignore in any aspect of cultural studies. In a society where changes were slow and foreign influences were few, an illusion of culture as homogeneous and static may have been easy to uphold, but in today’s ever-increasing flux of cultural change, the perspective of transculturality is more satisfactory in understanding human identity constructions. Compared with concepts such as interculturality, multiculturality, or hybridity, which all may have some relevance for describing cultural encounters, but which often presuppose the notion of cultural essentialism, the concept of transculturality has the advantage of recognising change and diversity, rather than focusing on boundaries or differences.
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9. |
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10. |
- Herbert, Juan Herrera, et al.
(författare)
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Implementation of CDIO Initiative In New European Education Programs in Raw Materials
- 2017
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Ingår i: EDULEARN17 Proceedings. - 2340-1117. - 9788469737774 ; , s. 6518-6526
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- EIT Raw Materials, one of the six Knowledge and Innovation Communities (KICs) initiated by the EIT (European Institute of Innovation and Technology) and funded by the European Commission, has the mission to boost competitiveness, growth and attractiveness of the European raw materials sector via radical innovation and guided entrepreneurship. It aims to significantly enhance innovation in the raw materials sector by the sharing of knowledge, information and expertise. This must generate a significant impact on European competitiveness and employment by driving and fostering innovation and empowering students, entrepreneurs and education partners driving toward the circular economy.To reach the vision, where the European Union’s industrial strength is based on a cost-efficient, secure, sustainable supply and use of raw materials, a new generation of skilled people entering industry, universities and research needs to be developed. Today’s technical MSc graduates in raw materials and especially primary resources (i.e. exploration, extraction, mining and mineral processing and metallurgy) meet the technical standards required by the raw materials industry across the full raw materials value chain and best suits large companies where they often act as specialists and experts. For small to medium enterprises as well as for our future engineers, other skills than technical are necessary.EIT Raw Materials will educate people that will have an intra- and entrepreneurial mind-set and will be able to develop their functions in new working environments, fostering the entrepreneurial and innovation skills, knowledge and attitudes needed for the entre- and intrapreneurs of tomorrowThe CDIO™ INITIATIVE is an innovative educational framework for producing the next generation of engineers. The framework provides students with an education stressing engineering fundamentals set in the context of Conceiving — Designing — Implementing — Operating (CDIO) real-world systems and products. There are no academic institutes in Europe that have yet applied CDIO for primary resource related MSc programs. Within the KIC EIT Raw Materials Academy, the overarching brand of all the KIC’s education activities are created in order to stimulate education activities and foster new ways of learning and teaching; an approved education project is focusing on the implementation of the CDIO methodology in primary resources linked programs. The project started in 2016 and focuses on faculty and pilot case development and the contributing partners are from academia, industry and research institutes. This project focuses on faculty development for an active and experimental learning by teaching the “technical” faculty through CDIO linked courses (entrepreneurship, business, etc.), communicative workshops, inspiration lectures and by involving the “business and entrepreneurial” faculty in exploration, mining, mineral processing and metallurgy related issues also through curriculum and pilot cases developed together with the industry.This paper describes how this education project is being developed within the EIT Raw Materials and will give an overview of the needed skillset of future engineers demanded in the Raw Materials primary sector. It presents key outputs about already developed and implemented activities in mining engineering and metallurgy related programs.
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