| 1. |
- Ceccato, Vania, Professor, 1968-, et al.
(författare)
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Lethal Violence in Brazil : A Systematic Review of Portuguese-Language Literature From 2000 to 2020
- 2021
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Ingår i: Criminal Justice Review. - : SAGE Open. - 0734-0168 .- 1556-3839. ; , s. 1-31
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Tidskriftsartikel (refereegranskat)abstract
- Reviewing national literature on homicides in Brazil, this article explores questions that relate to the nature, trends, determinants, and impact of these crimes on society, as well as interventions to combat this type of violence. The article contributes to the international literature by reviewing and critically discussing a sample of 112 theses on homicides from the Portuguese-language literature using the Brazilian Digital Library of Theses and Dissertations from 2000 to 2020. Highlighting an issue that primarily affects young, poor Black men, the article helps advocate for a better understanding of other types of lethal violence that affect women, LGBQTI and other minorities. The article calls for a better understanding of the role of the state, the police and other criminal justice actors as generators and/or controllers of violence, as well as the need for other perspectives on homicide prevention, which include the microsituational aspects of killing, organized crime, and interaction between the individual and the environment.
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| 2. |
- Ceccato, Vania, Professor, 1968-, et al.
(författare)
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Pandemic Restrictions and Spatiotemporal Crime Patterns in New York, São Paulo, and Stockholm
- 2022
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Ingår i: Journal of Contemporary Criminal Justice. - : Sage Publications. - 1043-9862 .- 1552-5406.
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Tidskriftsartikel (refereegranskat)abstract
- Studies are showing evidence of the effect of changes in routine activities due to the 2020 COVID-19 pandemic on crime levels in many cities worldwide. This study evaluates the potential impact of the COVID-19 pandemic on temporal and spatial patterns of crime in three major cities under very different national contexts. Each of the three countries and cities experienced different levels of pandemic restrictions and societal closure. The cities of New York (the United States), São Paulo (Brazil), and Stockholm (Sweden) were selected as cases. Temporal quantitative methods, spatial statistics techniques, and Geographical Information System (GIS) underlie the methodology used in this study. Findings show that there is a statistically significant break in the trend in crime levels after the stay-at-home orders were implemented in New York City, São Paulo, and Stockholm in the first months of 2020; the only exception was for murder. Such an impact varies by crime type and city context, but increases again after a few months, indicating how fast crime and criminals adapt. Residential burglary decreased, whereas nonresidential burglary increased overall. Changes in the levels and geography of vehicle thefts were observed, with an overall increase of significant cold spots but, in several cases, also solidification of existing crime concentrations in known crime attractors and in some deprived areas.
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| 3. |
- Ceccato, Vania, et al.
(författare)
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The geography of homicide in Sao Paulo, Brazil
- 2007
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Ingår i: Environment and planning A. - : SAGE Publications. - 0308-518X .- 1472-3409. ; 39:7, s. 1632-1653
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Tidskriftsartikel (refereegranskat)abstract
- The authors investigate geographical patterns of homicide in Sao Paulo, Brazil. The geography of crime in developing world cities has been an underresearched area in part because of the lack of good-quality, geocoded offence data. In the case of Sao Paulo the availability of a new digital police dataset has provided the opportunity to improve our understanding of its crime patterns. The authors report the testing of hypotheses about the spatial variation in homicide rates. This variation is explained by poverty, situational conditions determined by differences in land use, and processes that indicate links with the geography of drug markets and the availability of firearms.
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| 4. |
- Hibar, Derrek P., et al.
(författare)
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Novel genetic loci associated with hippocampal volume
- 2017
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Ingår i: Nature Communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 8
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Tidskriftsartikel (refereegranskat)abstract
- The hippocampal formation is a brain structure integrally involved in episodic memory, spatial navigation, cognition and stress responsiveness. Structural abnormalities in hippocampal volume and shape are found in several common neuropsychiatric disorders. To identify the genetic underpinnings of hippocampal structure here we perform a genome-wide association study (GWAS) of 33,536 individuals and discover six independent loci significantly associated with hippocampal volume, four of them novel. Of the novel loci, three lie within genes (ASTN2, DPP4 and MAST4) and one is found 200 kb upstream of SHH. A hippocampal subfield analysis shows that a locus within the MSRB3 gene shows evidence of a localized effect along the dentate gyrus, subiculum, CA1 and fissure. Further, we show that genetic variants associated with decreased hippocampal volume are also associated with increased risk for Alzheimer's disease (r(g) = -0.155). Our findings suggest novel biological pathways through which human genetic variation influences hippocampal volume and risk for neuropsychiatric illness.
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| 5. |
- Satizabal, Claudia L., et al.
(författare)
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Genetic architecture of subcortical brain structures in 38,851 individuals
- 2019
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Ingår i: Nature Genetics. - : Nature Publishing Group. - 1061-4036 .- 1546-1718. ; 51:11, s. 1624-
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Tidskriftsartikel (refereegranskat)abstract
- Subcortical brain structures are integral to motion, consciousness, emotions and learning. We identified common genetic variation related to the volumes of the nucleus accumbens, amygdala, brainstem, caudate nucleus, globus pallidus, putamen and thalamus, using genome-wide association analyses in almost 40,000 individuals from CHARGE, ENIGMA and UK Biobank. We show that variability in subcortical volumes is heritable, and identify 48 significantly associated loci (40 novel at the time of analysis). Annotation of these loci by utilizing gene expression, methylation and neuropathological data identified 199 genes putatively implicated in neurodevelopment, synaptic signaling, axonal transport, apoptosis, inflammation/infection and susceptibility to neurological disorders. This set of genes is significantly enriched for Drosophila orthologs associated with neurodevelopmental phenotypes, suggesting evolutionarily conserved mechanisms. Our findings uncover novel biology and potential drug targets underlying brain development and disease.
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| 6. |
- Thompson, Paul M., et al.
(författare)
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The ENIGMA Consortium : large-scale collaborative analyses of neuroimaging and genetic data
- 2014
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Ingår i: BRAIN IMAGING BEHAV. - : Springer Science and Business Media LLC. - 1931-7557 .- 1931-7565. ; 8:2, s. 153-182
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Tidskriftsartikel (refereegranskat)abstract
- The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) Consortium is a collaborative network of researchers working together on a range of large-scale studies that integrate data from 70 institutions worldwide. Organized into Working Groups that tackle questions in neuroscience, genetics, and medicine, ENIGMA studies have analyzed neuroimaging data from over 12,826 subjects. In addition, data from 12,171 individuals were provided by the CHARGE consortium for replication of findings, in a total of 24,997 subjects. By meta-analyzing results from many sites, ENIGMA has detected factors that affect the brain that no individual site could detect on its own, and that require larger numbers of subjects than any individual neuroimaging study has currently collected. ENIGMA's first project was a genome-wide association study identifying common variants in the genome associated with hippocampal volume or intracranial volume. Continuing work is exploring genetic associations with subcortical volumes (ENIGMA2) and white matter microstructure (ENIGMA-DTI). Working groups also focus on understanding how schizophrenia, bipolar illness, major depression and attention deficit/hyperactivity disorder (ADHD) affect the brain. We review the current progress of the ENIGMA Consortium, along with challenges and unexpected discoveries made on the way.
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