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1.	Dahl, F, et al. (author) Imaging single DNA molecules for high precision NIPT 2018 In: Scientific reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 8:1, s. 4549- Journal article (peer-reviewed)abstract Cell-free DNA analysis is becoming adopted for first line aneuploidy screening, however for most healthcare programs, cost and workflow complexity is limiting adoption of the test. We report a novel cost effective method, the Vanadis NIPT assay, designed for high precision digitally-enabled measurement of chromosomal aneuploidies in maternal plasma. Reducing NIPT assay complexity is achieved by using novel molecular probe technology that specifically label target chromosomes combined with a new readout format using a nanofilter to enrich single molecules for imaging and counting without DNA amplification, microarrays or sequencing. The primary objective of this study was to assess the Vanadis NIPT assay with respect to analytical precision and clinical feasibility. Analysis of reference DNA samples indicate that samples which are challenging to analyze with low fetal-fraction can be readily detected with a limit of detection determined at <2% fetal-fraction. In total of 286 clinical samples were analysed and 30 out of 30 pregnancies affected by trisomy 21 were classified correctly. This method has the potential to make cost effective NIPT more widely available with more women benefiting from superior detection and false positive rates.
2.	SCHULMAN, S, et al. (author) A comparison of six weeks with six months of oral anticoagulant therapy after a first episode of venous thromboembolism. Duration of Anticoagulation Trial Study Group 1995 In: The New England journal of medicine. - 0028-4793. ; 332:25, s. 1661-1665 Journal article (peer-reviewed)
3.	Schulman, S, et al. (author) The duration of oral anticoagulant therapy after a second episode of venous thromboembolism. The Duration of Anticoagulation Trial Study Group 1997 In: The New England journal of medicine. - 0028-4793. ; 336:6, s. 393-398 Journal article (peer-reviewed)
4.	Schulman, S, et al. (author) The significance of hypofibrinolysis for the risk of recurrence of venous thromboembolism. Duration of Anticoagulation (DURAC) Trial Study Group 1996 In: Thrombosis and haemostasis. - 0340-6245. ; 75:4, s. 607-611 Journal article (peer-reviewed)
5.	Blaurock, MG, et al. (author) Impact of Glucose Measuring Systems and Sample Type on Diagnosis Rates of Diabetes Mellitus 2018 In: Diabetes therapy : research, treatment and education of diabetes and related disorders. - : Springer Science and Business Media LLC. - 1869-6953. ; 9:5, s. 2029-2041 Journal article (peer-reviewed)
6.	Neubig, S, et al. (author) Analytical robustness of nine common assays: frequency of outliers and extreme differences identified by a large number of duplicate measurements 2017 In: Biochemia medica. - 1330-0962. ; 27:1, s. 192-198 Journal article (peer-reviewed)
7.	Petersmann, A, et al. (author) Diagnosis of late presenting subarachnoid hemorrhage: comparison of methods for cerebrospinal fluid ferritin 2014 In: Scandinavian journal of clinical and laboratory investigation. - : Informa UK Limited. - 1502-7686 .- 0036-5513. ; 74:6, s. 524-526 Journal article (peer-reviewed)
8.	Suchsland, J, et al. (author) Optimizing centrifugation of coagulation samples in laboratory automation 2014 In: Clinical chemistry and laboratory medicine. - : Walter de Gruyter GmbH. - 1437-4331 .- 1434-6621. ; 52:8, s. 1187-1191 Journal article (peer-reviewed)
9.	Armocida, A, et al. (author) Vitamin C plasma concentrations and leg weakness in the forelegs of growing pigs 2001 In: Journal of veterinary medicine. A, Physiology, pathology, clinical medicine. - : Wiley. - 0931-184X. ; 48:3, s. 165-178 Journal article (peer-reviewed)
10.	Beckert, V, et al. (author) Insertion experience of women and health care professionals in the Kyleena® Satisfaction Study 2020 In: The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception. - : Informa UK Limited. - 1473-0782. ; 25:3, s. 182-189 Journal article (peer-reviewed)

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Type of publication: journal article (122); conference paper (14)

Type of content: peer-reviewed (104); other academic/artistic (32)

Author/Editor: Kallner, A (95); Kallner, G (17); Kallner, HK (11); Lopez, J (6); Blomback, M (6); Petersmann, A. (6); show more...; Ruck, A (5); Nauck, M (5); Sylven, C (5); Malmqvist, K (5); Franco-Cereceda, A (5); Khatami, Z (5); Drvota, V (5); Pettersson, T (5); Skeppholm, M (4); Lindblom, D (4); Donders, G (4); Kopp Kallner, H (4); Petrescu, A (3); Gemzell-Danielsson, ... (3); CARLSSON, A (3); Walter, H (3); Lind, B (3); Gustafsson, C (3); Schulman, S (3); Lindmarker, P (3); Sarkar, N (3); Larfars, G (3); Svensson, E. (3); Albage, A (3); van der Linden, J (3); Ohlsson, A (3); AlKhalili, F (3); Kenny, D. (3); Owall, A (3); Antovic, JP (3); Johnsson, H (3); Hauck, B (3); Hjorth, M. (3); Fagrell, B (3); Bauerfeind, A (3); Linder, O (3); Malm, C. (3); Nicol, P (3); Egberg, N (3); Granqvist, S (3); BOBERG, J (3); Hulting, J (3); Zvolanek, M (3); Leijd, B (3); show less...

University: Karolinska Institutet (132); Uppsala University (7); Royal Institute of Technology (3); University of Gothenburg (2); Linköping University (2); Lund University (2); show more...; Örebro University (1); The Swedish School of Sport and Health Sciences (1); show less...

Language: English (136)

Research subject (UKÄ/SCB): Medical and Health Sciences (5); Natural sciences (2); Engineering and Technology (1); Social Sciences (1)

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