| 1. |
- Alzghoul, Ahmad, et al.
(författare)
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Data stream mining for increased functional product availability awareness
- 2011
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Ingår i: Functional Thinking for Value Creation. - Berlin, Heidelberg : Springer Berlin/Heidelberg. - 9783642196881 - 9783642196898 ; , s. 237-241
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Konferensbidrag (refereegranskat)abstract
- Functional Products (FP) and Product Service Systems (PSS) may be seen as integrated systems comprising hardware and support services. For such offerings, availability is key. Little research has been done on integrating Data Stream Management Systems (DSMS) for monitoring (parts of) a FP to improve system availability. This paper introduces an approach for how data stream mining may be applied to monitor hardware being part of a Functional Product. The result shows that DSMS have the potential to significantly support continuous availability awareness of industrial systems, especially important when the supplier is to supply a function with certain availability.
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| 2. |
- Hagvall, Lina, 1978, et al.
(författare)
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Contact allergy to citral and its constituents geranial and neral, coupled with reactions to the prehapten and prohapten geraniol
- 2020
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Ingår i: Contact Dermatitis. - : Wiley. - 0105-1873 .- 1600-0536. ; 82:1, s. 31-38
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Tidskriftsartikel (refereegranskat)abstract
- Background Citral is commonly used as a fragrance and flavor material and consists of the aldehydes geranial and neral. Citral is included in fragrance mix (FM) II. Geranial and neral have also been identified in autoxidation of geraniol, a fragrance compound present in FM I. Objectives To study contact allergy to citral, geranial, and neral, and concomitant reactivity to oxidized geraniol and fragrance markers of the baseline series. Methods A total of 1476 dermatitis patients with suspected allergic contact dermatitis were patch tested using geranial, neral, and citral, all 3.5% petrolatum (pet.) as well as geraniol 6.0% and oxidized geraniol 11% pet. in addition to the Swedish baseline series. Results Frequencies of positive reactions to citral, geranial, and neral were 2.9%, 3.4% and 1.9%, respectively. Together, citral and geranial gave 4.2% positive patch test reactions in consecutive dermatitis patients. In patients with positive reactions to citral or its components, 25% to 34% reacted to FM II and 61% reacted to oxidized geraniol. Conclusions Patch testing with citral, its components, or oxidized geraniol detects contact allergic reactions not detected using the baseline series. Patch testing with pure geraniol was shown to be of little value. Geranial and neral, although closely chemically related, are concluded to be separate haptens.
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| 3. |
- Hagvall, Lina, 1978, et al.
(författare)
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Contact allergy to oxidized geraniol among Swedish dermatitis patients-A multicentre study by the Swedish Contact Dermatitis Research Group
- 2018
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Ingår i: Contact Dermatitis. - : Wiley. - 0105-1873 .- 1600-0536. ; 79:4, s. 232-238
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Tidskriftsartikel (refereegranskat)abstract
- Background: Geraniol is a widely used fragrance terpene, and is included in fragrance mix I. Geraniol is prone to autoxidation, forming the skin sensitizers geranial, neral, and geraniol-7-hydroperoxide. Oxidized geraniol has previously been patch tested in 1 clinic, giving 1% to 4.6% positive reactions in consecutive patients when tested at 2% to 11%. Aim: To compare test reactions to pure and oxidized geraniol, to compare 2 different test concentrations of oxidized geraniol and to investigate the pattern of concomitant reactions to fragrance markers of the baseline series in a multicentre setting. Methods: One thousand four hundred and seventy-six consecutive patients referred for patch testing were patch tested with geraniol 6% pet. and oxidized geraniol 6% and 11% pet. Results: Pure geraniol 6% pet., oxidized geraniol 6% pet. and oxidized geraniol 11% pet. gave 1%, 3% and 8% positive patch test reactions and 0.7%, 3% and 5% doubtful reactions, respectively. Approximately 50% of the patients with doubtful reactions to oxidized geraniol 6% pet. had positive reactions to oxidized geraniol 11% pet. Conclusions: Oxidized geraniol 11% pet. provides better detection than oxidized geraniol 6% pet. As most patients reacted only to oxidized geraniol, it is important to explore further whether oxidized geraniol should be included in a baseline patch test series.
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| 4. |
- Johnsson, Helena, et al.
(författare)
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En pedagogisk idé för ingenjörsutbildningarna vid Luleå tekniska universitet
- 2009
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Konferensbidrag (refereegranskat)abstract
- Utmärkande för Luleå tekniska universitet (LTU) har länge varit närheten mellan studenterna och lärarna vilket har manifesterats genom klassrumsundervisning, lärartillgänglighet, mindre studiegrupper, koncentrerade campus etc. Undervisningsformerna har dock ändrats till att idag omfatta dels klassiska föreläsningar i stora studentgrupper, men också projektarbete i team där totalt sett 1/3 av all undervisning vid Luleå tekniska universitet sker i projektform. En fråga har ställts: Har Luleå tekniska universitet idag en gemensam pedagogisk idé för ingenjörsutbildningarna? I så fall är ytterligare en fråga hur denna pedagogiska idé tar sig uttryck i organisationen?Intervjuer med 40 aktiva lärare vid Luleå tekniska universitet har genomförts av projektgruppen (tillika författarna) varpå svaren har grupperats och analyserats i fjorton olika teman. Från dessa teman har sedan fyra hörnstenar i en definition av en pedagogisk idé aggregerats. Formuleringen av den pedagogiska idén lyder: Ett aktivt lärande för yrkeslivet – i branschnära projekt och med god vetenskaplig grund tränas förmågan att arbeta som ingenjör genom coachning från lärare i ett nära och öppet klimat. Idén har antagits av den tekniska fakultetsnämnden vid Luleå tekniska universitet och verifierats på institutionerna. Exempel på implementering och hur den pedagogiska idén aktivt verkar presenteras i artikeln.
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| 5. |
- Karlberg, Magnus, et al.
(författare)
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Simulation driven processing function development, offering and operation
- 2012
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Ingår i: Proceedings of the ASME 2012 International Mechanical Engineering Congress & Exposition IMECE2012. - New York : American Society of Mechanical Engineers. - 9780791845196 ; , s. 1561-1572
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Konferensbidrag (refereegranskat)abstract
- In today’s industry, functional provision is becoming more and more important, necessitating increased simulation support. In this paper, the objective is to present a modeling and simulation approach for simulation-driven design (SDD) to support function development. The scope of this paper is simulation support for developing hardware equipment used in processing industry. The research is founded on industrial needs identified through two parallel interview-based studies in the Swedish process industry. Both companies explore doing business with functional products rather than hardware, in scenarios where the responsibility for and availability of the functions may remain with the service provider. One as-is and one future (to-be) scenario are presented. A decomposition of a general processing function (applicable to both companies) describes how the companies transfer machine input to output specifications. The decomposition includes customer and provider value and the paper demonstrates, as part of the results and based on the SDD approach, how that value may be increased through evaluation and prioritization. Additionally, the SDD approach shows that it is possible to identify a set of solutions which meet the specified requirements, supporting evaluation and prioritization of business offers and activities.
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| 6. |
- Karlberg, Magnus, et al.
(författare)
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State of the art in simulation-driven design
- 2013
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Ingår i: International Journal of Product Development. - Bucks, United Kingdom : InderScience Publishers. - 1477-9056 .- 1741-8178. ; 18:1, s. 68-87
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Tidskriftsartikel (refereegranskat)abstract
- During the last few decades, and in order to increase product development efficiency, simulations strategies have been developed to guide designers towards better solutions rather than to verify suggested and basically unevaluated solutions. Such approaches are often called Simulation Driven Design (SDD), which is of interest in this review. The objective of this paper is to show the research evolution of SDD and identify the state of the art in SDD methodology. The literature review comprises several hundred references, of which 79 are included in this paper. The results comprise the state of the art in simulation driven design including the history, various definitions, criteria and effects of using SDD approaches.
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| 7. |
- Karlsson, Lennart, et al.
(författare)
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Editorial
- 2013
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Ingår i: International Journal of Product Development. - 1477-9056 .- 1741-8178. ; 18:1, s. 1-2
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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| 8. |
- Karlsson, Lennart, et al.
(författare)
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Editorial
- 2013
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Ingår i: International Journal of Product Development. - Bucks, United Kingdom : InderScience Publishers. - 1477-9056 .- 1741-8178. ; 18:1, s. 1-2
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Tidskriftsartikel (refereegranskat)
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| 9. |
- Karlsson, Lennart, et al.
(författare)
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Mechanics of materials and structures: a simulation-driven design approach
- 2011
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Ingår i: Journal of Mechanics of Materials and Structures. - Berkeley, USA : Mathematical Sciences Publishers. - 1559-3959 .- 2157-5428. ; 6:1-4, s. 277-301
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Tidskriftsartikel (refereegranskat)abstract
- Engineering product development has developed considerably over the past decade. In order for industry to keep up with continuously changing requirements, it is necessary to develop new and innovative simulation methods. However, few tools and methods for simulation-driven design have been applied in industrial settings and proven to actually drive the development and selection of the ideal solution. Such tools, based on fundamental equations, are the focus of this paper. In this paper the work is based on two cases of mechanics of materials and structures: welding and rotor dynamical simulations. These two examples of simulation-driven design indicate that a larger design space can be explored and that more possible solutions can be evaluated. Therefore, the approach improves the probability of innovations and finding optimal solutions. A calibrated block dumping approach can be used to increase the efficiency of welding simulations when many simulations are required.
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| 10. |
- Lindström, John, et al.
(författare)
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A development process for Functional Products : hardware, software, service support system and management of operation
- 2012
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Ingår i: International Journal of Product Development. - : InderScience Publishers. - 1477-9056 .- 1741-8178. ; 16:3/4, s. 284-303
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Tidskriftsartikel (refereegranskat)abstract
- The development process for a Functional Product (FP) is complex and there is a need to coordinate, monitor, control and share information as well as to communicate properly among the parties involved in the process. This paper proposes a conceptual development process to manage the FP development, including development of hardware, software, service support system, and how to manage the operation of an FP. Further, challenges related to the integrated development of FPs are also discussed.
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