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Agglomeration, clusters and entrepreneurship : Studies in regional economic development
- 2014
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Samlingsverk (redaktörskap) (övrigt vetenskapligt/konstnärligt)abstract
- Regional economic development has experienced considerable dynamism over recent years. Perhaps the most notable cases were the rise of China and India to emergent country status by the turn of the millennium. With time now for hindsight, this book identifies some of the key forces behind these development successes, namely agglomeration, clusters and entrepreneurship.
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| 2. |
- Allamani, Allaman, et al.
(författare)
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Contextual Determinants of Alcohol Consumption Changes and Preventive Alcohol Policies : A 12-Country European Study in Progress 2011
- 2011
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Ingår i: Substance Use & Misuse. - : Informa UK Limited. - 1082-6084 .- 1532-2491. ; 46:10, s. 1288-1303
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Tidskriftsartikel (refereegranskat)abstract
- Beginning with France in the 1950s, alcohol consumption has decreased in Southern European countries with few or no preventive alcohol policy measures being implemented, while alcohol consumption has been increasing in Northern European countries where historically more restrictive alcohol control policies were in place, even though more recently they were loosened. At the same time, Central and Eastern Europe have shown an intermediate behavior. We propose that country-specific changes in alcohol consumption between 1960 and 2008 are explained by a combination of a number of factors: (1) preventive alcohol policies and (2) social, cultural, economic, and demographic determinants. This article describes the methodology of a research study designed to understand the complex interactions that have occurred throughout Europe over the past five decades. These include changes in alcohol consumption, drinking patterns and alcohol-related harm, and the actual determinants of such changes
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| 4. |
- Andersson, Börje, et al.
(författare)
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Thermal stresses in large butt-welded plates
- 1981
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Ingår i: Journal of thermal stresses. - : Informa UK Limited. - 0149-5739 .- 1521-074X. ; 4:3-4, s. 491-500
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Tidskriftsartikel (refereegranskat)abstract
- In shipyard panel-production lines several rectangular plates ae butt welded to form large panels. One problem is the tendency of hot cracking in the end portion of the butt weld. In this paper transient temperature fields and stress fields in butt-welded plates are calculated using the finite-element method. The calculations are performed for different welding speeds, for different heat inputs, and for one-sided and two-sided welding.
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| 5. |
- Andersson, Håkan, 1944, et al.
(författare)
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Astatine-211-labeled antibodies for treatment of disseminated ovarian cancer: an overview of results in an ovarian tumor model
- 2003
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Ingår i: Clin Cancer Res. - 1078-0432. ; 9:10 Pt 2
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Tidskriftsartikel (refereegranskat)abstract
- PURPOSE: The aim of the study was to establish and refine a preclinical model to alpha-immunoradiotherapy of ovarian cancer. EXPERIMENTAL DESIGN: At-211 was produced by cyclotron irradiation of a bismuth-209 target and isolated using a novel dry distillation procedure. Monoclonal antibodies were radiohalogenated with the intermediate reagent N-succinimidyl 3-(trimethylstannyl)benzoate and characterized in terms of radiochemical yield and in vitro binding properties. In vitro OVCAR-3 cells were irradiated using an external Cobalt-60 beam, as reference, or At-211-albumin and labeled antibody. Growth assays were used to establish cell survival. A Monte Carlo program was developed to simulate the energy imparted and the track length distribution. Nude mice were used for studies of WBC depression, with various activities of Tc-99m antibodies, as reference, and At-211 antibodies. In efficacy studies, OVCAR-3 cells were inoculated i.p., and animals were treated 2 weeks later. The animals were either dissected 6 weeks later or followed-up for long-term survival. RESULTS: A rapid distillation procedure, as well as a rapid and high-yield, single-pot labeling procedure, was achieved. From growth inhibition data, the relative biological effectiveness of the alpha-emission for OVCAR-3 cells was estimated to be approximately 5, which is in the same range as found in vivo for hematological toxicity. At-211 MOv18 was found to effectively inhibit the development of tumors and ascites, also resulting in long-term survival without significant toxic effect. CONCLUSIONS: Use of the short-range, high-linear energy transfer alpha-emitter At-211 conjugated to a surface epitope-recognizing monoclonal antibody appears to be highly efficient without significant toxicity in a mouse peritoneal tumor model, urging a Phase I clinical trial.
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| 6. |
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| 7. |
- Andersson, Martin, et al.
(författare)
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Multinationals in the Knowledge Economy : A case study of AstraZeneca in Sweden
- 2010
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Ingår i: Repositioning Europe and America for Growth. - Berlin : LIT Verlag. - 9783643107763
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Bokkapitel (refereegranskat)abstract
- This report presents a case study of the role of a large R&D intensive multinational company for a small open economy. The case study examines the role of AstraZeneca in the Swedish economy, i.e. an economy dominated by multinational companies. The purpose of the report is to analyze the interaction of AstraZeneca’s units in Sweden with the rest of the Swedish economy, and the Swedish innovation system in particular. We analyze the company’s role as an employer in the private sector, its transaction links with other Swedish firms and its role for Sweden’s exports. In a second perspective we focus on the company’s role in the Swedish knowledge economy and innovation system. The report analyses the company as a node for knowledge flows in the Swedish economy and innovation system, and its role as an employer of highly educated and skilled workers in Sweden.Our analysis of the Swedish units’ interaction with the rest of the Swedish economy shows that ’traditional’ couplings in the form of transactions with Swedish suppliers are limited. It is instead the company’s position in the ‘knowledge economy’ that makes its presence in Sweden important.
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| 8. |
- Andersson, Martin, et al.
(författare)
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Multinationals in the Knowledge Economy : A case study of AstraZeneca in Sweden
- 2008
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Multinational companies play a large and growing role in the world economy. Theycontribute about 10 percent to world GDP and about two thirds to global exports. Inthe vast majority of the countries in the world, the presence of multinationals has alsobeen growing over time. This report presents a case study of the role of a large multinational company, activein one of the most R&D and knowledge intensive industries of the world, withestablishments in a small open economy. The case study examines the role ofAstraZeneca in the Swedish economy, i.e. an economy dominated by multinationalcompanies. They account for almost all of Sweden’s aggregate investments in privateR&D, over 90 percent of the country’s exports and imports as well as a significantshare of the total number of employees in the private sector. The analyses in the reportmake it possible to assess the importance of the local presence of such a largeknowledge-intensive multinational for Sweden.
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| 9. |
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| 10. |
- Andersson, Martin, et al.
(författare)
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Preface
- 2013
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Ingår i: Innovation and Growth. - : Oxford University Press (OUP).
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Bokkapitel (refereegranskat)
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