| 1. |
- Insulander Björk, Klara L, 1982, et al.
(författare)
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Commercial thorium fuel manufacture and irradiation: Testing (Th,Pu)O-2 and (Th,U)O-2 in the "Seven-Thirty" program
- 2015
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Ingår i: Annals of Nuclear Energy. - : Elsevier BV. - 0306-4549 .- 1873-2100. ; 75, s. 79-86
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Tidskriftsartikel (refereegranskat)abstract
- Thorium based fuels are being tested in the Halden Research Reactor in Norway with the aim of producing the data necessary for licensing of these fuels in today's light water reactors. The fuel types currently under irradiation are thorium oxide fuel with plutonium as the fissile component, and uranium fuel with thorium as an additive for enhancement of thermo-mechanical and neutronic fuel properties. Fuel temperatures, rod pressures and dimensional changes are monitored on-line for quantification of thermo-mechanical behavior and fission gas release. Preliminary irradiation results show benefits in terms of lower fuel temperatures, mainly caused by improved thermal conductivity of the thorium fuels. In parallel with the irradiation, a manufacturing procedure for thorium-plutonium mixed oxide fuel is developed with the aim to manufacture industrially relevant high-quality fuel pellets for the next phase of the irradiation campaign.
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| 2. |
- Insulander Björk, Klara L, 1982, et al.
(författare)
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Thermal-mechanical performance modeling of thorium-plutonium oxide fuel and comparison with on-line irradiation data
- 2015
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Ingår i: Journal of Nuclear Materials. - : Elsevier BV. - 0022-3115. ; 467, s. 876-885
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Tidskriftsartikel (refereegranskat)abstract
- Thorium-plutonium Mixed OXide (Th-MOX) fuel is considered for use in light water reactors fuel due to some inherent benefits over conventional fuel types in terms of neutronic properties. The good material properties of ThO2 also suggest benefits in terms of thermal-mechanical fuel performance, but the use of Th-MOX fuel for commercial power production demands that its thermal-mechanical behavior can be accurately predicted using a well validated fuel performance code. Given the scant operational experience with Th-MOX fuel, no such code is available today. This article describes the first phase of the development of such a code, based on the well-established code FRAPCON 3.4, and in particular the correlations reviewed and chosen for the fuel material properties. The results of fuel temperature calculations with the code in its current state of development are shown and compared with data from a Th-MOX test irradiation campaign which is underway in the Halden research reactor. The results are good for fresh fuel, whereas experimental complications make it difficult to judge the adequacy of the code for simulations of irradiated fuel. (C) 2015 Elsevier B.V. All rights reserved.
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| 3. |
- Ivchenko, N, et al.
(författare)
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Disturbance of plasma environment in the vicinity of the Astrid-2 microsatellite
- 2001
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Ingår i: ANNALES GEOPHYSICAE. - : EUROPEAN GEOPHYSICAL SOCIETY. - 0992-7689. ; 19:6, s. 655-666
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Tidskriftsartikel (refereegranskat)abstract
- The presence of a satellite disturbs the ambient plasma. The charging of the spacecraft creates a sheath around it, and the motion of the satellite creates a wake disturbance. This modification of the plasma environment introduces difficulties in measurin
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| 4. |
- Sindi, S., et al.
(författare)
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Multimodal Preventive Trial for Alzheimer’s Disease : MIND-ADmini Pilot Trial Study Design and Progress
- 2022
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Ingår i: The Journal of Prevention of Alzheimer's Disease. - : Serdi-Editions. - 2274-5807 .- 2426-0266. ; 9:1, s. 30-39
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Tidskriftsartikel (refereegranskat)abstract
- Background: Interventions simultaneously targeting multiple risk factors and mechanisms are most likely to be effective in preventing cognitive impairment. This was indicated in the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) testing a multidomain lifestyle intervention among at-risk individuals. The importance of medical food at the early symptomatic disease stage, prodromal Alzheimer’s disease (AD), was emphasized in the LipiDiDiet trial. The feasibility and effects of multimodal interventions in prodromal AD are unclear. Objectives: To evaluate the feasibility of an adapted FINGER-based multimodal lifestyle intervention, with or without medical food, among individuals with prodromal AD. Methods: MIND-ADmini is a multinational proof-of-concept 6-month randomized controlled trial (RCT), with four trial sites (Sweden, Finland, Germany, France). The trial targeted individuals with prodromal AD defined using the International Working Group-1 criteria, and with vascular or lifestyle-related risk factors. The parallel-group RCT includes three arms: 1) multimodal lifestyle intervention (nutritional guidance, exercise, cognitive training, vascular/metabolic risk management and social stimulation); 2) multimodal lifestyle intervention+medical food (Fortasyn Connect); and 3) regular health advice/ care (control group). Primary outcomes are feasibility and adherence. Secondary outcomes are adherence to the individual intervention domains and healthy lifestyle changes. Results: Screening began on 28 September 2017 and was completed on 21 May 2019. Altogether 93 participants were randomized and enrolled. The intervention proceeded as planned. Conclusions: For the first time, this pilot trial tests the feasibility and adherence to a multimodal lifestyle intervention, alone or combined with medical food, among individuals with prodromal AD. It can serve as a model for combination therapy trials (non-pharma, nutrition-based and/or pharmacological interventions).
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