| 1. |
- Bouyoucef, S E, et al.
(författare)
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Poster Session 2 : Monday 4 May 2015, 08
- 2015
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Ingår i: European Heart Journal Cardiovascular Imaging. - : Oxford University Press (OUP). - 2047-2404 .- 2047-2412. ; 16 Suppl 1
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Tidskriftsartikel (refereegranskat)
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| 2. |
- Ferreira, Mjv, et al.
(författare)
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Poster Session 3 : Tuesday 5 May 2015, 08
- 2015
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Ingår i: European Heart Journal Cardiovascular Imaging. - : Oxford University Press (OUP). - 2047-2404 .- 2047-2412. ; 16 Suppl 1
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Tidskriftsartikel (refereegranskat)
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| 3. |
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| 4. |
- Patyra, K., et al.
(författare)
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Congenital Hypothyroidism and Hyperthyroidism Alters Adrenal Gene Expression, Development, and Function
- 2022
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Ingår i: Thyroid. - : Mary Ann Liebert Inc. - 1050-7256 .- 1557-9077. ; 32:4, s. 459-471
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Tidskriftsartikel (refereegranskat)abstract
- Background: The human adrenal cortex undergoes several rapid remodeling steps during its lifetime. In rodents, similar remodeling occurs postnatally in the "X-zone" layer through unknown mechanisms. Furthermore, little is known regarding the impact of thyroid hormone (TH) on adrenal glands in humans.Methods: To investigate the impact of TH on adrenal pathophysiology, we created two genetic murine models mimicking human nonautoimmune hypothyroidism and hyperthyroidism. Moreover, we analyzed serum thyrotropin (TSH) and steroid hormone concentrations in patients diagnosed with congenital hypothyroidism and premature adrenarche (PA).Results: We found that TH receptor beta-mediated hypertrophy of the X-zone significantly elevated the adrenal weights of hyperthyroid women. In the hypothyroid model, the X-zone was poorly developed in both sexes. Moreover, large reciprocal changes in the expression levels of genes that regulate adrenal cortical function were observed with both models. Unexpectedly, up- and downregulation of several genes involved in catecholamine synthesis were detected in the adrenal glands of the hypothyroid and hyperthyroid models, respectively. Furthermore, TSH and adrenal steroid concentrations correlated positively in pediatric patients with congenital hypothyroidism and PA.Conclusions: Our results revealed that congenital hypothyroidism and hyperthyroidism functionally affect adrenal gland development and related steroidogenic activity, as well as the adrenal medulla.
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| 5. |
- Pellegrino, T, et al.
(författare)
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Moderated Poster Session 3 : Monday 4 May 2015, 10
- 2015
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Ingår i: European Heart Journal Cardiovascular Imaging. - : Oxford University Press (OUP). - 2047-2404 .- 2047-2412. ; 16 Suppl 1
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Tidskriftsartikel (refereegranskat)
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| 6. |
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| 7. |
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| 8. |
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| 9. |
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| 10. |
- Kero, J., et al.
(författare)
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MU radar head echo observations of the 2011 October Draconids
- 2012
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Ingår i: Monthly notices of the Royal Astronomical Society. - Hoboken, NJ : Wiley-Blackwell. - 0035-8711 .- 1365-2966. ; 424:3, s. 1799-1806
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Tidskriftsartikel (refereegranskat)abstract
- On 2011 October 8, the Earth passed through a stream of dust ejected by the comet 21P/GiacobiniZinner during its perihelion passage of the year 1900, causing an outburst of October Draconid meteors. 13 Draconids were observed among similar to 6300 meteor head echoes with precisely determined orbits during an observational campaign ranging from October 8 05:00 ut to October 9 13:00 ut with the Shigaraki middle and upper atmosphere (MU) radar in Japan (34 degrees.85?N and 136 degrees.10?E). The meteor outburst occurred while the Draconid radiant was descending below and 2?h later rising up above the horizon. Therefore, 11 of the detections were from very low (<15 degrees) elevation. The detection altitudes of the Draconids were high compared to sporadic meteors of the same velocity and radiant elevation. The weighted mean geocentric velocity of the 13 Draconids was 20.6 +/- 0.4?km?s-1, and the weighted mean radiant located at right ascension alpha = 263 degrees.3 +/- 0 degrees.6 and declination delta = 55 degrees.8 +/- 0 degrees.2.
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