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Sökning: WFRF:(Khan Murad)

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1.
  • Khan, Adil, et al. (författare)
  • Predictive modeling for depth of wear of concrete modified with fly ash : A comparative analysis of genetic programming-based algorithms
  • 2024
  • Ingår i: Case Studies in Construction Materials. - : Elsevier. - 2214-5095. ; 20
  • Tidskriftsartikel (refereegranskat)abstract
    • There has been increasing growth in incorporating fly ash as a supplementary cementitious material in concrete mixtures due to its potential to enhance the durability and strength properties of concrete. However, there is a lack of research on predicting the depth of wear of fly ash-based concrete. The laboratory methods available for estimating the depth of wear often involve destructive and expensive tests. Therefore, to avoid costly and laborious tests, this study utilized two machine learning methods, including multi-expression programming (MEP) and gene expression programming (GEP), to predict the depth of wear of fly ash-modified concrete. A comprehensive dataset of 216 experimental records was compiled from published studies for model training and validation. This extensive dataset encompasses the depth of wear as the target variable, along with nine explanatory parameters, namely fly ash, cement content, fine and coarse aggregate, water content, plasticizer, age of concrete, air-entraining agent, and testing time. The models were trained with 70% of the data, and the remaining 30% of data was used for validating the models. The models were developed by a continuous trial-and-error process and iterative refinement of hyperparameters until optimal results were achieved. The efficacy of the models was assessed via multiple statistical indicators. Furthermore, the SHapley Additive exPlanation (SHAP) was utilized for the interpretability of the model prediction from both global and local perspectives. The GEP model exhibited excellent accuracy with a correlation coefficient (R) of 0.989 (training) and 0.992 (validation). Similarly, the MEP model provided prediction accuracy with R values of 0.965 and 0.968 for training and validation sets, respectively. In addition, the MEP and GEP models outperformed the traditional multi-linear regression model. The SHAP interpretation revealed that testing time and age have a higher contribution in determining the depth of wear. The findings of this study can assist practitioners and designers in avoiding costly and laborious tests for durability assessment and promoting sustainable use of fly ash in the construction sector.
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2.
  • Ademuyiwa, Adesoji O., et al. (författare)
  • Determinants of morbidity and mortality following emergency abdominal surgery in children in low-income and middle-income countries
  • 2016
  • Ingår i: BMJ Global Health. - : BMJ Publishing Group Ltd. - 2059-7908. ; 1:4
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Child health is a key priority on the global health agenda, yet the provision of essential and emergency surgery in children is patchy in resource-poor regions. This study was aimed to determine the mortality risk for emergency abdominal paediatric surgery in low-income countries globally.Methods: Multicentre, international, prospective, cohort study. Self-selected surgical units performing emergency abdominal surgery submitted prespecified data for consecutive children aged <16 years during a 2-week period between July and December 2014. The United Nation's Human Development Index (HDI) was used to stratify countries. The main outcome measure was 30-day postoperative mortality, analysed by multilevel logistic regression.Results: This study included 1409 patients from 253 centres in 43 countries; 282 children were under 2 years of age. Among them, 265 (18.8%) were from low-HDI, 450 (31.9%) from middle-HDI and 694 (49.3%) from high-HDI countries. The most common operations performed were appendectomy, small bowel resection, pyloromyotomy and correction of intussusception. After adjustment for patient and hospital risk factors, child mortality at 30 days was significantly higher in low-HDI (adjusted OR 7.14 (95% CI 2.52 to 20.23), p<0.001) and middle-HDI (4.42 (1.44 to 13.56), p=0.009) countries compared with high-HDI countries, translating to 40 excess deaths per 1000 procedures performed.Conclusions: Adjusted mortality in children following emergency abdominal surgery may be as high as 7 times greater in low-HDI and middle-HDI countries compared with high-HDI countries. Effective provision of emergency essential surgery should be a key priority for global child health agendas.
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3.
  • Pirkis, Jane, et al. (författare)
  • Suicide numbers during the first 9-15 months of the COVID-19 pandemic compared with pre-existing trends : An interrupted time series analysis in 33 countries
  • 2022
  • Ingår i: eClinicalMedicine. - : Elsevier. - 2589-5370. ; 51
  • Tidskriftsartikel (refereegranskat)abstract
    • Background Predicted increases in suicide were not generally observed in the early months of the COVID-19 pandemic. However, the picture may be changing and patterns might vary across demographic groups. We aimed to provide a timely, granular picture of the pandemic's impact on suicides globally. Methods We identified suicide data from official public-sector sources for countries/areas-within-countries, searching websites and academic literature and contacting data custodians and authors as necessary. We sent our first data request on 22nd June 2021 and stopped collecting data on 31st October 2021. We used interrupted time series (ITS) analyses to model the association between the pandemic's emergence and total suicides and suicides by sex-, age-and sex-by-age in each country/area-within-country. We compared the observed and expected numbers of suicides in the pandemic's first nine and first 10-15 months and used meta-regression to explore sources of variation. Findings We sourced data from 33 countries (24 high-income, six upper-middle-income, three lower-middle-income; 25 with whole-country data, 12 with data for area(s)-within-the-country, four with both). There was no evidence of greater-than-expected numbers of suicides in the majority of countries/areas-within-countries in any analysis; more commonly, there was evidence of lower-than-expected numbers. Certain sex, age and sex-by-age groups stood out as potentially concerning, but these were not consistent across countries/areas-within-countries. In the meta-regression, different patterns were not explained by countries' COVID-19 mortality rate, stringency of public health response, economic support level, or presence of a national suicide prevention strategy. Nor were they explained by countries' income level, although the meta-regression only included data from high-income and upper-middle-income countries, and there were suggestions from the ITS analyses that lower-middle-income countries fared less well. Interpretation Although there are some countries/areas-within-countries where overall suicide numbers and numbers for certain sex- and age-based groups are greater-than-expected, these countries/areas-within-countries are in the minority. Any upward movement in suicide numbers in any place or group is concerning, and we need to remain alert to and respond to changes as the pandemic and its mental health and economic consequences continue. Copyright (C) 2022 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
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4.
  • 2019
  • Tidskriftsartikel (refereegranskat)
  •  
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