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Sökning: WFRF:(Khandelwal Ashish)

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1.
  • Khandelwal, Navneet, et al. (författare)
  • Determinants of motor, language, cognitive, and global developmental delay in children with complicated severe acute malnutrition at the time of discharge : An observational study from Central India
  • 2020
  • Ingår i: PLOS ONE. - : PUBLIC LIBRARY SCIENCE. - 1932-6203. ; 15:6
  • Tidskriftsartikel (refereegranskat)abstract
    • Background Undernutrition leads to impaired psychosocial and cognitive development. This study explored the developmental status of children with complicated severe acute malnutrition (SAM) and correlated it with various risk factors for SAM. Methods and findings We recruited 100 children with SAM and no other associated significant health issues during the recovery phase of treatment using the Bayley Scales of Infant and Toddler Development III prior to discharge from the nutritional rehabilitation unit in R D Gardi Medical College, Ujjain, Central India. We also assessed composite developmental scores, developmental age equivalents, and average differences in developmental age. Risk factors for developmental delay were identified in children with complicated SAM. The results revealed that 75%, 75%, and 63% of children with SAM exhibited delay in motor (mean score: 78.22), language (mean score: 83.97), and cognitive (mean score: 78.06) domains, respectively. A total of 63% children exhibited delay by an average of 4-7 months in the total developmental age. The proportion of children with delay in motor, language, and cognitive domains was determined. An increased risk of global developmental delay was observedin children with a low birth weight (adjusted odds ratio [aOR]: 18.06, 95%CI: 2.08-156.56; P = 0.009), having working mothers (aOR: 17.54, 95%CI: 3.02-102.59; P = 0.001), weight-for-age less than three standard deviations (aOR: 6.09, 95%CI: 1.08-34.10; P = 0.04), and presence of severe anemia (aOR: 16.34, 95%CI: 2.94-90.73; P = 0.001). Conclusions The results indicated that children with SAM exhibit developmental delay across all domains. Identifying multiple modifiable risk factors for developmental delay in children with SAM will be helpful in devising early interventional strategies in low-middle income countries; however, the exact timing of such interventions should be investigated.
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3.
  • Pistidda, Claudio, et al. (författare)
  • Synthesis of amorphous Mg(BH4)(2) from MgB2 and H-2 at room temperature
  • 2010
  • Ingår i: Journal of Alloys and Compounds. - : Elsevier BV. - 0925-8388. ; 508:1, s. 212-215
  • Tidskriftsartikel (refereegranskat)abstract
    • Due to its high hydrogen content and its favourable overall thermodynamics magnesium tetrahydroborate has been considered interesting for hydrogen storage applications. In this work we show that unsolvated amorphous magnesium tetrahydroborate can be obtained by reactive ball milling of commercial MgB2 under 100 bar hydrogen atmosphere. The material was characterized by solid-state NMR which showed the characteristic features of Mg(BH4)(2), together with those of higher borohydride species. High pressure DSC and TPD-MS showed thermal behaviour similar to that of Mg(BH4)(2) but with broadened signals. In situ synchrotron X-ray powder diffraction confirmed the amorphous state of the material and showed the typical crystalline decomposition products of Mg(BH4)(2) at elevated temperatures. (C) 2010 Elsevier B.V. All rights reserved.
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