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Sökning: WFRF:(Khashayar Patricia)

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1.
  • Foessl, Ines, et al. (författare)
  • Bone Phenotyping Approaches in Human, Mice and Zebrafish – Expert Overview of the EU Cost Action GEMSTONE (“GEnomics of MusculoSkeletal traits TranslatiOnal NEtwork”)
  • 2021
  • Ingår i: Frontiers in Endocrinology. - : Frontiers Media SA. - 1664-2392. ; 12
  • Forskningsöversikt (refereegranskat)abstract
    • A synoptic overview of scientific methods applied in bone and associated research fields across species has yet to be published. Experts from the EU Cost Action GEMSTONE (“GEnomics of MusculoSkeletal Traits translational Network”) Working Group 2 present an overview of the routine techniques as well as clinical and research approaches employed to characterize bone phenotypes in humans and selected animal models (mice and zebrafish) of health and disease. The goal is consolidation of knowledge and a map for future research. This expert paper provides a comprehensive overview of state-of-the-art technologies to investigate bone properties in humans and animals – including their strengths and weaknesses. New research methodologies are outlined and future strategies are discussed to combine phenotypic with rapidly developing –omics data in order to advance musculoskeletal research and move towards “personalised medicine”.
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2.
  • Gharibzadeh, Safoora, et al. (författare)
  • Contribution of bone turnover markers (BTMs) and vitamin D to bone health in Iranian elderly women
  • 2024
  • Ingår i: Journal of Diabetes & Metabolic Disorders. - : SPRINGER INT PUBL AG. - 2251-6581.
  • Tidskriftsartikel (refereegranskat)abstract
    • PurposeWhile only a few postmenopausal women exhibit biochemical signs of hypovitaminosis D, it has been shown that vitamin D insufficiency has detrimental effects on the overall skeleton mineralization, bone turnover rate, and may be a significant risk factor for osteoporosis and fracture. We evaluated the concurrent effect of Vitamin D levels and biochemical markers of bone turnover on bone health of postmenopausal women.MethodsThe present study was conducted within the framework of the Bushehr Elderly Health (BEH) program, a population-based prospective cohort study being conducted in Bushehr, a southern province of Iran. In summary, 400 persons from participants of the second stage were selected; serum bone turnover markers (bone-specific alkaline phosphatase (bALP), amino-terminal procollagen propeptides of type I collagen (P1NP), osteocalcin (OC), tartrate-resistant acid phosphatase isoenzyme 5b (TRAP)) and vitamin D were measured. Vitamin D deficiency was defined as serum 25(OH) D below 20 ng/ml, and Bone health was considered in terms of Osteoporosis and degraded bone microarchitecture.ResultsThe number of partially or significantly degraded microstructure based on TBS was higher than the number of osteoporotic women based on BMD. Women with higher CTX levels were more prone to being degraded microarchitecture. Although we couldn't find any association between vitamin D deficiency and bone health, when we considered the vitamin D levels in univariable modelling, the effect of it was significant.ConclusionsIn this study, only CTX was found to be significantly correlated with TBS while BMD was associated with CTX, OC, and TRAP.
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3.
  • Lorenzoni, Patricia, 1975, et al. (författare)
  • ur Borderlands / La Frontera av Gloria Anzaldúa
  • 2016
  • Ingår i: Tidskriften Kritiker (978-91-88431-02-8).
  • Konstnärligt arbete (övrigt vetenskapligt/konstnärligt)abstract
    • Översättning av dikter ur Borderlands / La Frontera av Gloria Anzaldúa (tillsammans med Patricia Lorenzoni)
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  • Resultat 1-3 av 3
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