| 1. |
- Hansson, Jonny, et al.
(författare)
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An optimisation strategy in a digital environment applied to neonatal chest imaging.
- 2005
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Ingår i: Radiation protection dosimetry. - : Oxford University Press (OUP). - 0144-8420 .- 1742-3406. ; 114:1-3, s. 278-85
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Tidskriftsartikel (refereegranskat)abstract
- The aim of this study was to find the optimum tube voltage for neonatal chest imaging in computed radiography. The study was designed to take full advantage of the benefits of digital imaging, for example, by comparing the tube voltages at constant effective dose. A phantom study using a living rabbit was first conducted. Images were collected at tube voltages ranging from 40 to 90 kV(p). The reproduction of four structures (central vessels, peripheral vessels, carina and thoracic vertebrae) was rated by 10 radiologists. The reproduction of both central and peripheral vessels was relatively independent of tube voltage. The carina was better reproduced at higher tube voltages whereas the opposite was true for the thoracic vertebrae. Based on the higher importance of the reproduction of the carina it was decided that 90 kV(p) was the optimal tube voltage. To validate the result from the phantom study, a follow-up study was conducted in which images of neonates collected at the tube voltage regularly used at Sahlgrenska University Hospital (70 kV(p)) were compared with images collected at the tube voltage proposed by the phantom study. The follow-up study confirmed the results from the phantom study that the reproduction of the carina was better at 90 than at 70 kV(p). In conclusion, for neonatal chest imaging-given the same effective dose-90 kVp gives better reproduction of important structures than the regularly used 70 kV(p).
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| 2. |
- Karltun, Johan, 1954-, et al.
(författare)
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Handbok för första linjens chefer
- 2022
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Bok (övrigt vetenskapligt/konstnärligt)abstract
- Från inledningen: Den här handboken vänder sig framför allt till dig som är första linjens chef i tillverkande industri. Första linjens chef definieras här som den första chefsnivån som har personalansvar. Det är den vanligaste chefspositionen och finns i alla företag med minst en chefsnivå. Det är en oerhört viktig funktion! Även forskningen lyfter fram första linjens chef som en nyckelposition för att skapa en väl fungerande och hållbar produktion.Du kanske är helt ny i rollen som chef och då är det här en hjälp till att förstå uppgiften. Eller så är du erfaren chef men ny i företaget, och kan behöva lite tips för att förstå och lyckas i ditt nya jobb. Slutligen hoppas vi erbjuda några guldkorn även för dig som är erfaren chef i ett företag som du känner sedan länge.Handboken vänder sig också till dig som har en roll i samarbete med första linjens chefer. Du kanske jobbar i linjen eller är teamledare, dvs ledare utan personalansvar. Du kanske är andra linjens chef eller har en stödfunktion till produktionen med ansvar för skydd och säkerhet, planering, kvalitetsutveckling, tekniskt underhåll, teknikutveckling, produktutveckling, logistik eller HR-funktioner. Vi hoppas att ni alla kan hitta användbara råd och lärdomar i handboken.I handboken vill vi tydliggöra arbetsinnehållet för första linjens chefer och hur det kan utvecklas. Vi gör det genom att beskriva rollen och arbetet som första linjens chef. Vi lägger också stor vikt vid att beskriva dynamiken och problemlösningen som hela tiden är närvarande. Dessutom vill vi peka på möjligheterna att systematiskt utveckla förutsättningarna för och förmågan att arbeta som chef i första linjen – så att du kan fungera och må bra i uppgiften på ett hållbart sätt eller stötta den personsom har denna roll. En första linjens chef har stor inverkan på både arbetsmiljön och effektiviteten inom sitt område. Även chefens arbetsmiljö är därför av stor vikt för att nå bra resultat inom dessa områden.
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| 3. |
- Karltun, Johan, 1954-, et al.
(författare)
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Handbook for front line managers
- 2023
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Bok (övrigt vetenskapligt/konstnärligt)abstract
- From the introduction: This handbook is aimed primarily at front line managers (FLMs) in manufacturing industries. Frontline manager is defined here as the first management level with personnel responsibility. It is the most common managerial position and is found in all companies that have at least one management level. It is an extremely important role. Research also highlights the FLM as a key position in the creation of well-functioning and sustainable production.You may be new to the role of being a manager, if so this book will help you to understand your tasks. If you are an experienced manager but new to the company, you will find some suggestions on how to succeed in your new job. Finally, we hope that we can offer some pearls of wisdom for those of you who are experienced managers in a company you have known for a long time.The handbook is also for you who collaborate with FLMs. You may be working in the line or as a team leader, which is a leader without personnel responsibility. You may be a second line manager or have a production support role with responsibility for protection and safety, planning and scheduling, quality development, technical maintenance, technological development, product development, logistics, HR functions or something else. We hope that the handbook will provide you all with useful advice and information.This handbook is intended to clarify the content of FLM’s work and how it can be developed. We do this by describing the role and work of the FLM but also the ever-present dynamics and problem-solving foundin the role. We also want to underscore opportunities for systematically developing the potential for and ability to work as a FLM. To enable you to work and thrive in the role in the long term or support someone else in this role. FLMs have a major impact on both work environment and efficiency within their area. As such, the manager’s work environment is also of great importance for success.
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| 4. |
- Thorell, Kaisa, et al.
(författare)
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Isolates from Colonic Spirochetosis in Humans Show High Genomic Divergence and Potential Pathogenic Features but Are Not Detected Using Standard Primers for the Human Microbiota
- 2019
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Ingår i: Journal of Bacteriology. - 0021-9193 .- 1098-5530. ; 201:21
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Tidskriftsartikel (refereegranskat)abstract
- Colonic spirochetosis, diagnosed based on the striking appearance in histological sections, still has an obscure clinical relevance, and only a few bacterial isolates from this condition have been characterized to date. In a randomized, population-based study in Stockholm, Sweden, 745 healthy individuals underwent colonoscopy with biopsy sampling. Of these individuals, 17 (2.3%) had colonic spirochetosis, which was associated with eosinophilic infiltration and a 3-fold-increased risk for irritable bowel syndrome (IBS). We aimed to culture the bacteria and perform whole-genome sequencing of the isolates from this unique representative population sample. From 14 out of 17 individuals with spirochetosis we successfully isolated, cultured, and performed whole-genome sequencing of in total 17 isolates, including the Brachyspira aalborgi type strain, 513A. Also, 16S analysis of the mucosaassociated microbiota was performed in the cases and nonspirochetosis controls. We found one isolate to be of the species Brachyspira pilosicoli; all remaining isolates were of the species Brachyspira aalborgi. Besides displaying extensive genetic heterogeneity, the isolates harbored several mucin-degrading enzymes and other virulenceassociated genes that could confer a pathogenic potential in the human colon. We also showed that 16S amplicon sequencing using standard primers for human microbiota studies failed to detect Brachyspira due to primer incompatibility. IMPORTANCE This is the first report of whole-genome analysis of clinical isolates from individuals with colonic spirochetosis. This characterization provides new opportunities in understanding the physiology and potentials of these bacteria that densely colonize the gut in the individuals infected. The observation that standard 16S amplicon primers fail to detect colonic spirochetosis may have major implications for studies searching for associations between members of the microbiota and clinical conditions such as irritable bowel syndrome (IBS) and should be taken into consideration in project design and interpretation of gastrointestinal tract microbiota in population-based and clinical settings.
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