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Numrering	Referens	Omslagsbild	Hitta
1.	Glikson, Michael, et al. (författare) 2021 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy: Developed by the Task Force on cardiac pacing and cardiac resynchronization therapy of the European Society of Cardiology (ESC) With the special contribution of the European Heart Rhythm Association (EHRA) 2021 Ingår i: European Heart Journal. - : OXFORD UNIV PRESS. - 0195-668X .- 1522-9645. ; 42:35, s. 3427-3520 Forskningsöversikt (refereegranskat)abstract n/a
2.	Glikson, Michael, et al. (författare) 2021 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy Developed by the Task Force on cardiac pacing and cardiac resynchronization therapy of the European Society of Cardiology (ESC) With the special contribution of the European Heart Rhythm Association (EHRA) 2022 Ingår i: Europace. - : OXFORD UNIV PRESS. - 1099-5129 .- 1532-2092. ; 24:1, s. 71-164 Tidskriftsartikel (refereegranskat)abstract n/a
3.	Lloyd, Michael S., et al. (författare) Design and rationale of the MODULAR ATP global clinical trial : A novel intercommunicative leadless pacing system and the subcutaneous implantable cardioverter-defibrillator 2023 Ingår i: HEART RHYTHM O2. - : Elsevier. - 2666-5018. ; 4:7, s. 448-456 Tidskriftsartikel (refereegranskat)abstract BACKGROUND: The subcutaneous implantable cardioverter-defibrillator (S-ICD) has demonstrated safety and efficacy for the treatment of malignant ventricular arrhythmias. However, a limitation of the S-ICD lies in the inability to either pace-terminate ventricular tachycardia or provide prolonged bradycardia pacing support.OBJECTIVE: The rationale and design of a prospective, single-arm, multinational trial of an intercommunicative leadless pacing system integrated with the S-ICD will be presented.METHODS: A technical description of the modular cardiac rhythm management (mCRM) system (EMPOWER leadless pacemaker and EMBLEM S-ICD) and the implantation procedure is provided. MODULAR ATP (Effectiveness of the EMPOWER (TM) Modular Pacing System and EMBLEM (TM) Subcutaneous ICD to Communicate Antitachycardia Pacing) is amulticenter, international trial enrolling up to 300 patients at risk of sudden cardiac death at up to 60 centers trial design. The safety endpoint of freedom from major complications related to the mCRM system or implantation procedure at 6 months and 2 years are significantly higher than 86% and 81%, respectively, and all-cause survival is significantly.85% at 2 years.RESULTS: Efficacy endpoints are that at 6 months mCRM communication success is significantly higher than 88% and the percentage of subjects with low and stable thresholds is significantly higher than 80%. Substudies to evaluate rate-responsive features and performance of the pacing module are also described.CONCLUSION: The MODULAR ATP global clinical trial will prospectively test the safety and efficacy of the first intercommunicating leadless pacing system with the S-ICD. This trial will allow for robust validation of device-device communication, pacing performance, rate responsiveness, and system safety.

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Resultat 1-3 av 3

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Typ av publikation: tidskriftsartikel (2); forskningsöversikt (1)

Typ av innehåll: refereegranskat (3)

Författare/redaktör: Knops, Reinoud E. (3); Braunschweig, Friede ... (2); Delgado, Victoria (2); Leclercq, Christophe (2); Coats, Andrew J. S. (2); Thylén, Ingela (2); visa fler...; Burri, Haran (2); Boriani, Giuseppe (2); Deharo, Jean-Claude (2); Michowitz, Yoav (2); Kronborg, Mads Brix (2); Glikson, Michael (2); Nielsen, Jens Cosedi ... (2); Keren, Andre (2); Merkely, Bela (2); Auricchio, Angelo (2); Diller, Gerhard-Paul (2); Barrabes, Jose A. (2); Starck, Christoph (2); Israel, Carsten W (2); Brignole, Michele (2); Kotecha, Dipak (2); Barbash, Israel Mosh ... (2); Blomström-Lundqvist, ... (1); Friedman, Paul A. (1); Mont, Lluis (1); Bongiorni, Maria Gra ... (1); Maria Tolosana, Jose (1); Tolosana, Maria (1); Lloyd, Michael S. (1); Brisben, Amy J. (1); Reddy, Vivek Y. (1); Boersma, Lucas V. A. (1); Burke, Martin C. (1); Cantillon, Daniel J. (1); Doshi, Rahul (1); Gras, Daniel (1); Kutalek, Steven P. (1); Neuzil, Petr (1); Roberts, Paul R. (1); Wright, David J. (1); Appl, Ursula (1); West, Julie (1); Carter, Nathan (1); Stein, Kenneth M. (1); visa färre...

Lärosäte: Linköpings universitet (2); Uppsala universitet (1)

Språk: Engelska (3)

Forskningsämne (UKÄ/SCB): Medicin och hälsovetenskap (3)

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