| 1. |
- Bylund, Linus, 1980, et al.
(författare)
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‘We must urgently learn to live differently’: the biopolitics of ESD for 2030
- 2022
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Ingår i: Environmental Education Research. - : Informa UK Limited. - 1350-4622 .- 1469-5871. ; 28:1, s. 40-55
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Tidskriftsartikel (refereegranskat)abstract
- Recently, the new global policy framework for implementing education for sustainable development (ESD) – ESD for 2030 – was launched officially. Drawing on Foucauldian theory, this paper explores biopolitical elements in ESD for 2030. The paper contributes to previous research on ESD policy by employing a biopolitical perspective, and by highlighting problematic aspects of the framework’s will to include and to adapt to different contexts. The analysis brings attention to the framework’s notions of life and to how different human populations are separated. Furthermore, the analysis of the framework demonstrates how notions of transformative pedagogy, community, and the individual, assume the functions of biopolitical techniques. The findings point to a biopolitical differentiation where rich and poor populations are assumed to need different educational interventions, adapted to their socio-economic contexts, in the global educational policy quest for sustainable development. Ultimately, we consider the potential of Foucauldian ethics as an affirmative alternative to the current mode of biopolitical differentiation in global ESD policy
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| 2. |
- Domeij, Rickard, et al.
(författare)
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Workshop on NLP for Reading and Writing : Resources, algorithms and tools
- 2008
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Ingår i: Swedish Conference of Language Technology, 2008. - 1736-6305. ; VOL. 3
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Konferensbidrag (refereegranskat)abstract
- New tools and media are creating new possibilities for people to communicate and find information over the Internet in a multilingual, global society. This is reflected in the fact that writers now write more in everyday life, typically create text directly on the computer and on the Internet (e.g. on blogs and other Web 2.0 technologies), and use new forms of writing in e-mails, web chats or SMS-messages on mobile phones. This concerns not only adults at work, but also children and youth. However, the new possibilities also put higher demands on our skills in using language for achieving our communicative goals in different situations. If the demands are not met, a great number of people will risk being excluded from participation in the emerging information society. Of course, this will have unfortunate consequences not only for the individual, but also for society at large. Therefore, there is a growing need for support in reading and writing. Certainly, there already exists writing tools such as authoring aids in word processors and instructional support in writing education. However, existing solutions have great difficulties meeting the growing need of support. In part, this is due to technical limitations of the tools in processing language, but also to the fact that these tools are poorly adjusted to different tasks, target user groups, genres and media.
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| 3. |
- Engdahl, Cecilia, et al.
(författare)
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Acetylcholinesterases from the Disease Vectors Aedes aegypti and Anopheles gambiae : Functional Characterization and Comparisons with Vertebrate Orthologues
- 2015
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Ingår i: PLOS ONE. - : Public Library of Science (PLoS). - 1932-6203. ; 10:10
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Tidskriftsartikel (refereegranskat)abstract
- Mosquitoes of the Anopheles (An.) and Aedes (Ae.) genus are principal vectors of human diseases including malaria, dengue and yellow fever. Insecticide-based vector control is an established and important way of preventing transmission of such infections. Currently used insecticides can efficiently control mosquito populations, but there are growing concerns about emerging resistance, off-target toxicity and their ability to alter ecosystems. A potential target for the development of insecticides with reduced off-target toxicity is the cholinergic enzyme acetylcholinesterase (AChE). Herein, we report cloning, baculoviral expression and functional characterization of the wild-type AChE genes (ace-1) from An. gambiae and Ae. aegypti, including a naturally occurring insecticide-resistant (G119S) mutant of An. gambiae. Using enzymatic digestion and liquid chromatography-tandem mass spectrometry we found that the secreted proteins were post-translationally modified. The Michaelis-Menten constants and turnover numbers of the mosquito enzymes were lower than those of the orthologous AChEs from Mus musculus and Homo sapiens. We also found that the G119S substitution reduced the turnover rate of substrates and the potency of selected covalent inhibitors. Furthermore, non-covalent inhibitors were less sensitive to the G119S substitution and differentiate the mosquito enzymes from corresponding vertebrate enzymes. Our findings indicate that it may be possible to develop selective non-covalent inhibitors that effectively target both the wild-type and insecticide resistant mutants of mosquito AChE.
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| 4. |
- Engdahl, Cecilia, et al.
(författare)
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Discovery of selective inhibitors targeting acetylcholinesterase 1 from disease-transmitting mosquitoes
- 2016
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Ingår i: Journal of Medicinal Chemistry. - : American Chemical Society (ACS). - 0022-2623 .- 1520-4804. ; 59:20, s. 9409-9421
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- Vector control of disease-transmitting mosquitoes is increasingly important due to the re-emergence and spread of infections such as malaria and dengue. We have conducted a high throughput screen (HTS) of 17,500 compounds for inhibition of the essential AChE1 enzymes from the mosquitoes Anopheles gambiae and Aedes aegypti. In a differential HTS analysis including the human AChE, several structurally diverse, potent, and selective noncovalent AChE1 inhibitors were discovered. For example, a phenoxyacetamide-based inhibitor was identified with a 100-fold selectivity for the mosquito over the human enzyme. The compound also inhibited a resistance conferring mutant of AChE1. Structure-selectivity relationships could be proposed based on the enzymes' 3D structures; the hits' selectivity profiles appear to be linked to differences in two loops that affect the structure of the entire active site. Noncovalent inhibitors of AChE1, such as the ones presented here, provide valuable starting points toward insecticides and are complementary to existing and new covalent inhibitors.
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| 5. |
- Hellberg, Sofie, 1979, et al.
(författare)
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Don efter population? Utbildning för hållbar utveckling och det globala biopolitiska GAPet
- 2018
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Ingår i: Pedagogisk forskning i Sverige. - 1401-6788. ; 23:3-4, s. 172-191
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Tidskriftsartikel (refereegranskat)abstract
- Världen över implementeras just nu det globala handlingsprogrammet för utbildning för hållbar utveckling (GAP). Ett återkommande budskap är att programmet förenar mänskligheten i en gemensam strävan mot ett bättre, jämlikare och ”grönare” liv för alla. Men är det verkligen så? Föreliggande artikel driver tesen att mänskligheten snarare delas upp. Med utgångspunkt i biopolitisk teoribildning sätter artikeln således fokus på differentiering och på vilka typer av kunskap(er) och livsstilsanspråk som olika populationer erbjuds i den hållbara utvecklingens namn. Ytterst är frågan om utbildning för hållbar utveckling riskerar att reproducera det globala gap som skiljer rika och fattiga människors livsstilar åt. Artikeln, som främst utgör ett teoretiskt och metodologiskt bidrag till den nordiska miljö- och hållbarhetsutbildningsforskningen, argumenterar för globala utblickar och biopolitiskt informerade undersökningar av hur GAP implementeras visavi olika populationer i olika sammanhang. Vidare diskuteras de metodologiska konsekvenserna av det biopolitiska perspektivet, d.v.s. vilka typer av frågor som blir relevanta att ställa och hur dessa kan beforskas.
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| 6. |
- Hellberg, Sofie, 1979, et al.
(författare)
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Governmentalities of automobility in times of climate change: competing logics of circulation and imaginaries of the (im)possible
- 2024
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Ingår i: Mobilities. - : Taylor & Francis. - 1745-0101 .- 1745-011X.
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Tidskriftsartikel (refereegranskat)abstract
- If we are to achieve climate change targets, transport systems need to transform. This article is concerned with the prospects of challenging the regime of automobility in urban areas. It employs a governmentality framework, alongside theories of automobility, in order to analyse mobility governmentalities in Gothenburg, Sweden. Gothenburg is an interesting case in the context of reducing car use given its identity as a ‘car city.’ Despite this, Gothenburg has high ambitions in terms of reducing car traffic. Reaching these goals are however associated with challenges: prognoses predict a continued increase in car traffic, and political acceptance is viewed as an obstacle. The article’s findings are based on semi-structured interviews with public officials and stakeholders, zooming in on (1) conflicting spatialities and temporalities (2) competing logics of circulation and pace and (3) mobility imaginaries of the (im)possible. We argue that while there are new logics entering urban mobility governmentalities as an effect of the climate transition, their possibilities to affect material change are confined because the movement and circulation of ‘people and things,’ ultimately represented by the private car, are closely tied to the way that freedom is exercised, understood and manifested in contemporary liberal societies.
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| 7. |
- Hellberg, Sofie, 1979, et al.
(författare)
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Minskad biltrafik – en förutsättning för stadens klimatomställning
- 2024
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Ingår i: Fem perspektiv på stadens omställning.
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- Dagens förhållningssätt till bilen som transportmedel och rädsla för medborgarnas missnöje gör det svårt att minska biltrafiken i staden. Det visar vår studie av Göteborgs Stad, där omställningen i praktiken går långsamt trots ambitiösa mål. För att nå klimatmålen krävs åtgärder som vågar omordna hierarkier i stadens transportsystem.
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| 8. |
- Hellberg, Sofie, 1979, et al.
(författare)
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Sustaining the life-chance divide? Education for sustainable development and the global biopolitical regime
- 2018
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Ingår i: Critical Studies in Education. - : Informa UK Limited. - 1750-8487 .- 1750-8495. ; 59:1, s. 93-107
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Tidskriftsartikel (refereegranskat)abstract
- What is being sustained in education for sustainable development (ESD)? Drawing on biopolitical theory, this article puts forth the hypothesis that it is in fact the very life-chance gulf that separates wealthy ‘sustainable’ mass consumers from poor ‘sustainable’ subsistence-level populations. Hence, in sharp contrast to the cosmopolitan buzz that characterizes the international policy discourse on ESD, it is argued that ESD feeds into the global life-chance divide as it prepares different populations for entirely different lives and lifestyles. In previous research that has dealt with global aspects of ESD, a dividing line can be drawn between scholars who emphasize tendencies towards neoliberal homogenization and those who highlight contingency, local re-articulations and spaces of contestation. This paper offers a third theoretical position that while sharing a deep unease with global neoliberal government is primarily concerned with its ‘will to divide’. As a corollary of this biopolitical perspective, the paper makes a case for critical empirical research that can lay bare the cracks and contradictions in the grand narrative of ESD as a cosmopolitan ethical enterprise.
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