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Sökning: WFRF:(Kolmodin Hedman B)

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  • Hillert, L, et al. (författare)
  • Environmental illness--effectiveness of a salutogenic group-intervention programme
  • 2002
  • Ingår i: Scandinavian journal of public health. - : SAGE Publications. - 1403-4948 .- 1651-1905. ; 30:3, s. 166-175
  • Tidskriftsartikel (refereegranskat)abstract
    • Aims: Hypersensitivity to electricity (HE) is a common form of reported environmental illness in Sweden. Functional somatic symptoms has been attributed to exposure to activated electrical equipment, but no causal relationship to electromagnetic fields has been proved. In many cases, traumatic life events and psychosocial stress can be identified, but patients often reject psychological explanations. This study evaluates the effectiveness of a new short-term group-intervention programme. Methods: A multidisciplinary team developed a short-term group-intervention programme, with a salutogenic approach that focuses on somatic and psychological reactions. Twenty-two patients (14 women and 8 men) who reported HE participated in eight weekly sessions of group meetings and physiotherapy. The effect of the programme was evaluated with regard to changes in work capacity, subjective well-being, coping ability, body awareness and physical fitness. Results: Contrary to our hypothesis physical fitness was not remarkably low. Muscular tension was reduced and body awareness increased but no significant change in symptoms was observed. Individual differences in progress were observed. Fourteen patients chose to continue with psychotherapy or physiotherapy. Conclusions: Participants accepted the programme very well. One important result was identification of underlying contributing factors and motivation for further therapy. A multidisciplinary group-intervention programme with a salutogenic approach might be a useful approach to patients with medically unexplained symptoms in primary healthcare.
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  • Sandstrom, T, et al. (författare)
  • Inflammatory cell response in bronchoalveolar lavage fluid after nitrogen dioxide exposure of healthy subjects: a dose-response study
  • 1991
  • Ingår i: European Respiratory Journal. - 1399-3003. ; 4:3, s. 332-339
  • Tidskriftsartikel (refereegranskat)abstract
    • The combination of environmental chamber exposure and bronchoalveolar lavage (BAL) was used to study the effects of the common air pollutant nitrogen dioxide (NO2). Eighteen healthy nonsmokers were exposed to NO2 during 20 min in an exposure chamber during light bicycle ergometer work. All subjects were examined with BAL at least 3 wks before exposure, as a reference. The subjects were re-examined with BAL, in groups of eight, 24 h after exposure to 4, 7 and 10 mg NO2.m.3 (2.25, 4.0 and 5.5 ppm), respectively. An inflammatory cell response was found after exposure to all concentrations. An increase in the number of lymphocytes in BAL fluid was observed after 7 and 10 mg.m.3 (p less than 0.05 and 0.02, respectively). An increase in the number of mast cells, that appears to be dose-dependent, was found after exposure to all concentrations. The proportion of lysozyme positive alveolar macrophages was elevated after exposure to 7 mg.m.3. The inflammatory mediators fibronectin, hyaluronan, angiotensin converting enzyme (ACE) and beta 2-microglobulin were unchanged by exposure. Due to the findings of inflammatory cell changes far below the peak exposure limits for work places in industrialized countries, 9-18 mg.m.3, the safety of these limits is questioned. Studies are in progress in our laboratory using BAL to evaluate the effects of repeated NO2 exposure.
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