| 1. |
- Bousquet, J, et al.
(författare)
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Nrf2-interacting nutrients and COVID-19: time for research to develop adaptation strategies
- 2020
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Ingår i: Clinical and translational allergy. - : Wiley. - 2045-7022. ; 10:1, s. 58-
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Tidskriftsartikel (refereegranskat)abstract
- There are large between- and within-country variations in COVID-19 death rates. Some very low death rate settings such as Eastern Asia, Central Europe, the Balkans and Africa have a common feature of eating large quantities of fermented foods whose intake is associated with the activation of the Nrf2 (Nuclear factor (erythroid-derived 2)-like 2) anti-oxidant transcription factor. There are many Nrf2-interacting nutrients (berberine, curcumin, epigallocatechin gallate, genistein, quercetin, resveratrol, sulforaphane) that all act similarly to reduce insulin resistance, endothelial damage, lung injury and cytokine storm. They also act on the same mechanisms (mTOR: Mammalian target of rapamycin, PPARγ:Peroxisome proliferator-activated receptor, NFκB: Nuclear factor kappa B, ERK: Extracellular signal-regulated kinases and eIF2α:Elongation initiation factor 2α). They may as a result be important in mitigating the severity of COVID-19, acting through the endoplasmic reticulum stress or ACE-Angiotensin-II-AT1R axis (AT1R) pathway. Many Nrf2-interacting nutrients are also interacting with TRPA1 and/or TRPV1. Interestingly, geographical areas with very low COVID-19 mortality are those with the lowest prevalence of obesity (Sub-Saharan Africa and Asia). It is tempting to propose that Nrf2-interacting foods and nutrients can re-balance insulin resistance and have a significant effect on COVID-19 severity. It is therefore possible that the intake of these foods may restore an optimal natural balance for the Nrf2 pathway and may be of interest in the mitigation of COVID-19 severity.
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| 2. |
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| 3. |
- Sabatini, F. M., et al.
(författare)
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sPlotOpen - An environmentally balanced, open-access, global dataset of vegetation plots
- 2021
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Ingår i: Global Ecology and Biogeography. - : Wiley. - 1466-822X .- 1466-8238.
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Tidskriftsartikel (refereegranskat)abstract
- Motivation Assessing biodiversity status and trends in plant communities is critical for understanding, quantifying and predicting the effects of global change on ecosystems. Vegetation plots record the occurrence or abundance of all plant species co-occurring within delimited local areas. This allows species absences to be inferred, information seldom provided by existing global plant datasets. Although many vegetation plots have been recorded, most are not available to the global research community. A recent initiative, called 'sPlot', compiled the first global vegetation plot database, and continues to grow and curate it. The sPlot database, however, is extremely unbalanced spatially and environmentally, and is not open-access. Here, we address both these issues by (a) resampling the vegetation plots using several environmental variables as sampling strata and (b) securing permission from data holders of 105 local-to-regional datasets to openly release data. We thus present sPlotOpen, the largest open-access dataset of vegetation plots ever released. sPlotOpen can be used to explore global diversity at the plant community level, as ground truth data in remote sensing applications, or as a baseline for biodiversity monitoring. Main types of variable contained Vegetation plots (n = 95,104) recording cover or abundance of naturally co-occurring vascular plant species within delimited areas. sPlotOpen contains three partially overlapping resampled datasets (c. 50,000 plots each), to be used as replicates in global analyses. Besides geographical location, date, plot size, biome, elevation, slope, aspect, vegetation type, naturalness, coverage of various vegetation layers, and source dataset, plot-level data also include community-weighted means and variances of 18 plant functional traits from the TRY Plant Trait Database. Spatial location and grain Global, 0.01-40,000 m(2). Time period and grain 1888-2015, recording dates. Major taxa and level of measurement 42,677 vascular plant taxa, plot-level records. Software format Three main matrices (.csv), relationally linked.
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| 4. |
- Kattge, Jens, et al.
(författare)
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TRY plant trait database - enhanced coverage and open access
- 2020
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Ingår i: Global Change Biology. - : Wiley-Blackwell. - 1354-1013 .- 1365-2486. ; 26:1, s. 119-188
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Tidskriftsartikel (refereegranskat)abstract
- Plant traits-the morphological, anatomical, physiological, biochemical and phenological characteristics of plants-determine how plants respond to environmental factors, affect other trophic levels, and influence ecosystem properties and their benefits and detriments to people. Plant trait data thus represent the basis for a vast area of research spanning from evolutionary biology, community and functional ecology, to biodiversity conservation, ecosystem and landscape management, restoration, biogeography and earth system modelling. Since its foundation in 2007, the TRY database of plant traits has grown continuously. It now provides unprecedented data coverage under an open access data policy and is the main plant trait database used by the research community worldwide. Increasingly, the TRY database also supports new frontiers of trait-based plant research, including the identification of data gaps and the subsequent mobilization or measurement of new data. To support this development, in this article we evaluate the extent of the trait data compiled in TRY and analyse emerging patterns of data coverage and representativeness. Best species coverage is achieved for categorical traits-almost complete coverage for 'plant growth form'. However, most traits relevant for ecology and vegetation modelling are characterized by continuous intraspecific variation and trait-environmental relationships. These traits have to be measured on individual plants in their respective environment. Despite unprecedented data coverage, we observe a humbling lack of completeness and representativeness of these continuous traits in many aspects. We, therefore, conclude that reducing data gaps and biases in the TRY database remains a key challenge and requires a coordinated approach to data mobilization and trait measurements. This can only be achieved in collaboration with other initiatives.
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| 5. |
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| 6. |
- Kehoe, Laura, et al.
(författare)
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Make EU trade with Brazil sustainable
- 2019
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Ingår i: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 364:6438, s. 341-
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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| 7. |
- Agerberg, Mattias, 1986, et al.
(författare)
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Sexual violence, gendered protection and support for intervention
- 2023
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Ingår i: Journal of Peace Research. - : SAGE Publications. - 0022-3433 .- 1460-3578. ; 60:5
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Tidskriftsartikel (refereegranskat)abstract
- The protection of civilians from human rights violations has increasingly become a global priority. The wars in Bosnia and Rwanda in the 1990s, and the development of the Women, Peace and Security framework have placed conflict-related sexual violence on the global protection agenda. Prior research has found that international attention to, and intervention in, conflicts is in fact more likely when there are reports of widespread sexual violence, regardless of overall conflict intensity. This article theorizes and empirically examines the micro-level underpinnings of these patterns. We hypothesize that individuals are more likely to support military intervention in conflicts with prevalent sexual violence as opposed to other types of conflict violence. The reason lies in gendered protection norms, based in benevolent sexism, that continue to have traction also in Western societies. In equivalent survey experiments carried out in the United States, the United Kingdom and Sweden, we find that support for international intervention is highest in sexual violence conflicts. In the United States and the United Kingdom, the responsibility to protect and gendered perceptions of victimhood mediate this effect. A follow-up experiment in the United States provides further evidence of a gendered protection norm as a core mechanism driving our results.
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| 8. |
- Kreft, A. K., et al.
(författare)
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Do gender patterns in diplomacy disappear over time?
- 2022
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Ingår i: European Journal of Politics and Gender. - 2515-1088. ; 5:3, s. 279-302
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Tidskriftsartikel (refereegranskat)abstract
- Existing scholarship points to gender patterns in diplomacy. This study examines such gender patterns in new ways, expecting women to be less likely to be ambassadors in states with more economic clout and in conflict-affected states, but more likely to serve as ambassadors in more gender-equal states. Most importantly, we examine whether these gender differences diminish over time. New data on ambassador appointments for Denmark, Sweden, the UK and the US spanning the period 1970–2015 reveal that whereas there are no gender differences with respect to postings to gender-equal states or states with domestic conflict, women are indeed less likely to be ambassadors in economically significant states and in states in inter-state conflict. Crucially, these patterns are not diminishing over time. This study opens up for future investigation into underlying mechanisms that explain the persistence of some gender patterns and the absence of others. © European Conference on Politics and Gender and Bristol University Press 2022.
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| 9. |
- Kreft, A. K., et al.
(författare)
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Imperfect Victims? Civilian Men, Vulnerability, and Policy Preferences
- 2024
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Ingår i: American Political Science Review. - 0003-0554. ; 118:1, s. 274-290
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Tidskriftsartikel (refereegranskat)abstract
- Who is deemed vulnerable and in need of protection has a bearing on important policy decisions, such as refugee acceptance or provision of aid. In war, dominant narratives construe women as paradigmatic victims, even while civilian men are disproportionately targeted in the most lethal forms of violence. How are such gender-essentialist notions reflected in public opinion? Do regular citizens have inaccurate perceptions of male victimization in war, and with what consequences for their policy preferences? We carried out survey experiments among U.S. and U.K. respondents on both real and hypothetical conflicts, where we emphasized or varied the gender of the victims. In support of our expectations, respondents consistently underestimate the victimization of men, perceive civilian male victims as less innocent, and hold anti-male biases when it comes to accepting refugees and providing aid. However, informing respondents of the vulnerability of male civilians to targeted assassinations and massacres mitigates these effects.
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