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Sökning: WFRF:(Lacalle L)

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2.
  • Suárez, A., et al. (författare)
  • Surface integrity and fatigue of non-conventional machined Alloy 718
  • 2019
  • Ingår i: Journal of Manufacturing Processes. - : Elsevier Ltd. - 1526-6125 .- 2212-4616. ; 48, s. 44-50
  • Tidskriftsartikel (refereegranskat)abstract
    • Alloy 718 is a high-strength, corrosion-resistant nickel chromium-based superalloy frequently used for applications, such as aerospace, marine, nuclear reactor and chemical industries, due to its outstanding inherent properties such as high strength and corrosion resistance at high temperatures together with good creep behaviour. Although, the use of conventional manufacturing processes is prevalent for their use on Alloy 718, alternative manufacturing technologies are gaining importance. This work compares the effects of alternative manufacturing processes, such as Abrasive water jet (AWJ), Wire Electrical Discharge Machining (WEDM) and ultrasound vibration assisted milling (UVAM) with conventional milling during the manufacture of Alloy 718 parts. Surface integrity, hardness, residual stress and fatigue strength obtained from these machining processes have been examined for cutting alloy 718. Results show that both residual stresses and surface roughness are correlated with fatigue strength. UVAM results shown an improvement on the surface integrity of the final workpiece. AWJ and WEDM show poorer results, further work on post-process technologies or process condition selection must be carry out to establish them as an alternative in Alloy 718 cutting operations.
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3.
  • Chaudhari, Rakesh, et al. (författare)
  • Effect of WEDM Process Parameters on Surface Morphology of Nitinol Shape Memory Alloy.
  • 2020
  • Ingår i: Materials. - : MDPI AG. - 1996-1944. ; 13:21
  • Tidskriftsartikel (refereegranskat)abstract
    • Nickel-titanium shape memory alloys (SMAs) have started becoming popular owing to their unique ability to memorize or regain their original shape from the plastically deformed condition by means of heating or magnetic or mechanical loading. Nickel-titanium alloys, commonly known as nitinol, have been widely used in actuators, microelectromechanical system (MEMS) devices, and many other applications, including in the biomedical, aerospace, and automotive fields. However, nitinol is a difficult-to-cut material because of its versatile specific properties such as the shape memory effect, superelasticity, high specific strength, high wear and corrosion resistance, and severe strain hardening. There are several challenges faced when machining nitinol SMA with conventional machining techniques. Noncontact operation of the wire electrical discharge machining (WEDM) process between the tool (wire) and workpiece significantly eliminates the problems of conventional machining processes. The WEDM process consists of multiple input parameters that should be controlled to obtain great surface quality. In this study, the effect of WEDM process parameters on the surface morphology of nitinol SMA was studied using 3D surface analysis, scanning electron microscopy (SEM), and energy-dispersive X-ray (EDX) analysis. 3D surface analysis results indicated a higher value of surface roughness (SR) on the top of the work surface and a lower SR on the bottom portion of the work surface. The surface morphology of the machined sample obtained at optimized parameters showed a reduction in microcracks, micropores, and globules in comparison with the machined surface obtained at a high discharge energy level. EDX analysis indicated a machined surface free of molybdenum (tool electrode).
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4.
  • Liang, Jia-xu, et al. (författare)
  • An individual patient data meta-analysis to determine cut-offs for and confounders of NAFLD-fibrosis staging with magnetic resonance elastography
  • 2023
  • Ingår i: Journal of Hepatology. - : Elsevier. - 0168-8278 .- 1600-0641. ; 79:3
  • Tidskriftsartikel (refereegranskat)abstract
    • Background & Aims: We conducted an individual patient data meta-analysis to establish stiffness cut-off values for magnetic resonance elastography (MRE) in staging liver fibrosis and to assess potential confounding factors. Methods: A systematic review of the literature identified studies reporting MRE data in patients with NAFLD. Data were obtained from the corresponding authors. The pooled diagnostic cut-off value for the various fibrosis stages was determined in a two-stage meta-analysis. Multilevel modelling methods were used to analyse potential confounding factors influencing the diagnostic accuracy of MRE in staging liver fibrosis. Results: Eight independent cohorts comprising 798 patients were included in the meta-analysis. The area under the receiver operating characteristic curve (AUROC) for MRE in detecting significant fibrosis was 0.92 (sensitivity, 79%; specificity, 89%). For advanced fibrosis, the AUROC was 0.92 (sensitivity, 87%; specificity, 88%). For cirrhosis, the AUROC was 0.94 (sensitivity, 88%, specificity, 89%). Cut-offs were defined to explore concordance between MRE and histopathology: 0.05) and high gamma-glutamyl transferase (GGT) concentration ( 120U/L) (odds ratio 3.388, 95% CI 1.577- 7.278, p <0.01] were significantly associated with elevated liver stiffness, and thus affecting accuracy in staging early fibrosis (F0-F1). Steatosis, as measured by magnetic resonance imaging proton density fat fraction, and body mass index(BMI) were not confounders. Conclusions: MRE has excellent diagnostic performance for significant, advanced fibrosis and cirrhosis in patients with NAFLD. Elevated inflammatory activity and GGT level may lead to overestimation of early liver fibrosis, but anthropometric measures such as BMI or the degree of steatosis do not. <(c)> 2023 The Author(s). Published by Elsevier B.V. on behalf of European Association for the Study of the Liver. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
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