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Sökning: WFRF:(Landahl Sten)

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  • Dahlin-Ivanoff, Synneve, 1950, et al. (författare)
  • Elderly persons in the risk zone: Design of a multidimensional, health-promoting, randomised three-armed controlled trial for "prefrail" people of 80+ years living at home
  • 2010
  • Ingår i: BMC geriatrics. - 1471-2318. ; 10:1
  • Tidskriftsartikel (refereegranskat)abstract
    • ABSTRACT: BACKGROUND: The very old (80+) are often described as a "frail" group that is particularly exposed to diseases and functional disability. They are at great risk of losing the ability to manage their activities of daily living independently. A health-promoting intervention programme might prevent or delay dependence in activities of daily life and the development of functional decline. Studies have shown that those who benefit most from a health-promoting and disease-preventive programme are persons with no, or discrete, activity restrictions. The three-armed study "Elderly in the risk zone" is designed to evaluate if multi-dimensional and multi-professional educational senior meetings are more effective than preventive home visits, and if it is possible to prevent or delay deterioration if an intervention is made when the persons are not so frail. In this paper the study design, the intervention and the outcome measures as well as the baseline characteristics of the study participants are presented. METHODS: The study is a randomised three-armed single-blind controlled trial with follow-ups 3 months, 1 and 2 years. The study group should comprise a representative sample of pre-frail 80-year old persons still living at home in two municipalities of Gothenburg. To allow for drop-outs, it was estimated that a total of about 450 persons would need to be included in the study. The participants should live in their ordinary housing and not be dependent on the municipal home help service or care. Further, they should be independent of help from another person in activities of daily living and be cognitively intact, having a score of 25 or higher as assessed with the Mini Mental State Examination (MMSE). DISCUSSION: We believe that the design of the study, the randomisation procedure, outcome measurements and the study protocol meetings should ensure the quality of the study. Furthermore, the multi-dimensionality of the intervention, the involvement of both the professionals and the senior citizens in the planning of the intervention should have the potential to effectively target the heterogeneous needs of the elderly.
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  • Dahlin-Ivanoff, Synneve, 1950, et al. (författare)
  • For whom is a health-promoting intervention effective? : Predictive factors for performing activities of daily living independently
  • 2016
  • Ingår i: BMC Geriatrics. - : BioMed Central. - 1471-2318 .- 1471-2318. ; 16
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Health-promoting interventions tailored to support older persons to remain in their homes, so-called “ageing in place” is important for supporting or improving their health. The health-promoting programme “Elderly Persons in the Risk Zone,” (EPRZ) was set up for this purpose and has shown positive results for maintaining independence in activities of daily living for older persons 80 years and above at 1- and 2 year follow-ups. The aim of this study was to explore factors for maintaining independence in the EPRZ health-promoting programme. Methods: Total of 459 participants in the original trial was included in the analysis; 345 in the programme arm and 114 in the control arm. Thirteen variables, including demographic, health, and programme-specific indicators, were chosen as predictors for independence of activities of daily living. Logistic regression was performed separately for participants in the health promotion programme and in the control arm. Results: In the programme arm, being younger, living alone and self-rated lack of tiredness in performing mobility activities predicted a positive effect of independence in activities of daily living at 1-year follow-up (odds ratio [OR] 1.18, 1.73, 3.02) and 2-year, (OR 1.13, 2.01, 2.02). In the control arm, being less frail was the only predictor at 1-year follow up (OR 1.6 1.09, 2.4); no variables predicted the outcome at the 2-year follow-up. Conclusions: Older persons living alone - as a risk of ill health - should be especially recognized and offered an opportunity to participate in health-promoting programmes such as “Elderly Persons in the Risk Zone”. Further, screening for subjective frailty could form an advantageous guiding principle to target the right population when deciding to whom health-promoting intervention should be offered. Trial registration: The original clinical trial was registered at ClinicalTrials.gov. Identifier: NCT00877058 , April 6, 2009. 
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  • Edberg, Anna-Karin, 1961-, et al. (författare)
  • Hur du använder läkemedel
  • 2009. - 1
  • Ingår i: Livslots för seniorer. - Stockholm : Hjälpmedelsinstitutet. ; , s. 65-75
  • Bokkapitel (populärvet., debatt m.m.)
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  • Edberg, Anna-Karin, et al. (författare)
  • Hur du använder läkemedel
  • 2009
  • Ingår i: Livslots för seniorer. - Stockholm : Hjälpmedelsinstitutet. ; :1, s. 65-75
  • Bokkapitel (övrigt vetenskapligt/konstnärligt)
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  • Ekerstad, Niklas, et al. (författare)
  • Acute care of severely frail elderly patients in a CGA-unit is associated with less functional decline than conventional acute care
  • 2017
  • Ingår i: Clinical Interventions in Aging. - : DOVE MEDICAL PRESS LTD. - 1176-9092 .- 1178-1998. ; 12, s. 1239-1248
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: A high percentage of individuals treated in specialized acute care wards are frail and elderly. Our aim was to study whether the acute care of such patients in a comprehensive geriatric assessment (CGA) unit is superior to care in a conventional acute medical care unit when it comes to activities of daily living (ADLs), frailty, and use of municipal help services. Patients and methods: A clinical, prospective, controlled trial with two parallel groups was conducted in a large county hospital in West Sweden and included 408 frail elderly patients, age 75 or older (mean age 85.7 years; 56% female). Patients were assigned to the intervention group (n=206) or control group (n=202). Primary outcome was decline in functional activity ADLs assessed by the ADL Staircase 3 months after discharge from hospital. Secondary outcomes were degree of frailty and use of municipal help services. Results: After adjustment by regression analyses, treatment in a CGA unit was independently associated with lower risk of decline in ADLs [odds ratio (OR) 0.093; 95% confidence interval (CI) 0.052-0.164; P amp;lt; 0.0001], and with a less prevalent increase in the degree of frailty (OR 0.229; 95% CI 0.131-0.400; P amp;lt; 0.0001). When ADLs were classified into three strata (independence, instrumental ADL-dependence, and personal ADL-dependence), changes to a more dependence-associated stratum were less prevalent in the intervention group (OR 0.194; 95% CI 0.085-0.444; P=0.0001). There was no significant difference between the groups in increased use of municipal help services (OR 0.682; 95% CI 0.395-1.178; P=0.170). Conclusion: Acute care of frail elderly patients in a CGA unit was independently associated with lesser loss of functional ability and lesser increase in frailty after 3 months.
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  • Ekerstad, Niklas, 1969-, et al. (författare)
  • Is the acute care of frail elderly patients in a comprehensive geriatric assessment unit superior to conventional acute medical care?
  • 2017
  • Ingår i: Clinical Interventions in Aging. - : DOVE MEDICAL PRESS LTD. - 1178-1998 .- 1176-9092. ; 12
  • Tidskriftsartikel (refereegranskat)abstract
    • Objective: The aim of this study was to investigate whether the acute care of frail elderly patients in a comprehensive geriatric assessment (CGA) unit is superior to the care in a conventional acute medical care unit. Design: This is a clinical, prospective, randomized, controlled, one-center intervention study. Setting: This study was conducted in a large county hospital in western Sweden. Participants: The study included 408 frail elderly patients, aged ≥75 years, in need of acute in-hospital treatment. The patients were allocated to the intervention group (n=206) or control group (n=202). Mean age of the patients was 85.7 years, and 56% were female. Intervention: This organizational form of care is characterized by a structured, systematic interdisciplinary CGA-based care at an acute elderly care unit. Measurements: The primary outcome was the change in health-related quality of life (HRQoL) 3 months after discharge from hospital, measured by the Health Utilities Index-3 (HUI-3). Secondary outcomes were all-cause mortality, rehospitalizations, and hospital care costs. Results: After adjustment by regression analysis, patients in the intervention group were less likely to present with decline in HRQoL after 3 months for the following dimensions: vision (odds ratio [OR] =0.33, 95% confidence interval [CI] =0.14–0.79), ambulation (OR =0.19, 95% CI =0.1–0.37), dexterity (OR =0.38, 95% CI =0.19–0.75), emotion (OR =0.43, 95% CI =0.22–0.84), cognition (OR = 0.076, 95% CI =0.033–0.18) and pain (OR =0.28, 95% CI =0.15–0.50). Treatment in a CGA unit was independently associated with lower 3-month mortality adjusted by Cox regression analysis (hazard ratio [HR] =0.55, 95% CI =0.32–0.96), and the two groups did not differ significantly in terms of hospital care costs (P>0.05). Conclusion: Patients in an acute CGA unit were less likely to present with decline in HRQoL after 3 months, and the care in a CGA unit was also independently associated with lower mortality, at no higher cost.
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  • Eklund, Kajsa, 1952, et al. (författare)
  • Long term outcome of frailty and ADL following "Continuum of care for frail elderly persons"
  • 2012
  • Ingår i: The Gerontologist. 2012 GSA Annual Scientific Meeting Abstracts. - 0016-9013 .- 1758-5341. ; 52:S1
  • Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
    • The current trend in Western societies facing a growing proportion of older people is to support frail older persons to remain in their homes as long as possible, so-called ageing in place. Older persons comprise a group whose reserve of strength is decreasing, and whose activity and participation levels will deteriorate with increasing frailty, often leading to dependence in daily activities. Frail older persons need integrated care from different caregivers at different care levels with multi-professional competences. An intervention study for frail community-dwelling older people was designed, creating a continuum of care from the hospital through and back to their own homes. Objectives were to evaluate its effects on activities of daily living (ADL) and frailty up to one year. The study design was a RCT with participants randomized to either the intervention or a control group with follow-ups at three-, six- and 12 months. The study group includes 161 older people who sought care at the emergency department at Mölndal hospital, Sweden, and discharged to their own homes. Inclusion criteria were age 80 and older or 65 to 79 with at least one chronic disease and dependent in ADL. Frailty was measured as a sum of eight core frailty indicators and ADL with the ADL staircase. The analyses were made on the basis of the intention-to-treat principle. At both three- and twelve-month follow-up the intervention group had a higher OR in improved number of ADL managed independently. There were no significant differences between the groups regarding frailty.
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