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- Bergström, Göran, 1964, et al.
(författare)
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Body weight at age 20 and in midlife is more important than weight gain for coronary atherosclerosis: Results from SCAPIS.
- 2023
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Ingår i: Atherosclerosis. - : Elsevier BV. - 1879-1484 .- 0021-9150. ; 373, s. 46-54
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Tidskriftsartikel (refereegranskat)abstract
- Elevated body weight in adolescence is associated with early cardiovascular disease, but whether this association is traceable to weight in early adulthood, weight in midlife or to weight gain is not known. The aim of this study is to assess the risk of midlife coronary atherosclerosis being associated with body weight at age 20, body weight in midlife and body weight change.We used data from 25,181 participants with no previous myocardial infarction or cardiac procedure in the Swedish CArdioPulmonary bioImage Study (SCAPIS, mean age 57 years, 51% women). Data on coronary atherosclerosis, self-reported body weight at age 20 and measured midlife weight were recorded together with potential confounders and mediators. Coronary atherosclerosis was assessed using coronary computed tomography angiography (CCTA) and expressed as segment involvement score (SIS).The probability of having coronary atherosclerosis was markedly higher with increasing weight at age 20 and with mid-life weight (p<0.001 for both sexes). However, weight increase from age 20 until mid-life was only modestly associated with coronary atherosclerosis. The association between weight gain and coronary atherosclerosis was mainly seen in men. However, no significant sex difference could be detected when adjusting for the 10-year delay in disease development in women.Similar in men and women, weight at age 20 and weight in midlife are strongly related to coronary atherosclerosis while weight increase from age 20 until midlife is only modestly related to coronary atherosclerosis.
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| 2. |
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| 3. |
- Allard, Christina, et al.
(författare)
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Rasbiologiskt språkbruk i statens rättsprocess mot sameby : DN Debatt 2015-06-11
- 2015
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Annan publikation (populärvet., debatt m.m.)abstract
- Statens hantering av forskningsresultat i rättsprocessen med Girjas sameby utgör ett hot mot Sverige som rättsstat och kunskapsnation. Åratal av svensk och internationell forskning underkänns och man använder ett språkbruk som skulle kunna vara hämtat från rasbiologins tid. Nu måste staten ta sitt ansvar och börja agera som en demokratisk rättsstat, skriver 59 forskare.
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| 4. |
- Andersson, Erik, 1966, et al.
(författare)
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Konsumtionens finansialisering
- 2014
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Ingår i: Konsumtionsrapporten 2014. - Göteborg : University of Gothenburg. ; , s. 35-39
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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| 5. |
- Andersson, Erik, 1966, et al.
(författare)
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Vardagslivets finansialisering
- 2016
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- I internationell samhällsvetenskaplig forskning används begreppet finansialisering för att förklara och beskriva den ökade betydelse som den finansiella ekonomin har i vår tid. I den här rapporten riktar vi sökarljuset mot hur vardagslivet omvandlats och hur finansiella logikers växande inflytande förändrar människors praktiker, relationer och identiteter (Martin 2002; Langley 2008). Rapporten anknyter därmed till en framväxande forskningsriktning som intresserar sig för, vad Haiven (2014) kallar, finansialiseringens kulturer. Med vardagslivets finansialisering åsyftar vi därmed hur människors vardagliga praktiker och meningssammanhang blir allt tätare sammanvävd med den finansiella ekonomins logiker, instrument och institutioner. Rapporten har karaktären av en antologi, i vilket ett antal forskare från olika samhällsvetenskapliga discipliner beskriver hur vardagslivet finansialiserats. Rapporten börjar med ett par studier av vad finansialiseringen kan betyda för enskilda människor och grupper i deras direkta vardag. Därefter rör vi oss ut mot de mer övergripande aspekterna och konsekvenserna av vardagslivets finansialisering, med frågor som hur denna utveckling stimulerats och hanterats av statliga aktörer och privata aktörer, samt vilka konsekvenser och innebörder finansialiseringen har haft för arbetslivet, välfärdsstaten och hur finansmarknaderna reglerats.
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| 6. |
- Andersson, Erik, 1966, et al.
(författare)
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Vardagslivets finansialisering
- 2016
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Ingår i: Ord & Bild. - 0030-4492. ; 2:2016, s. 38-47
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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| 7. |
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| 8. |
- Basu, Swaraj, et al.
(författare)
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Accurate mapping of mitochondrial DNA deletions and duplications using deep sequencing
- 2020
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Ingår i: PLoS Genetics. - : Public Library of Science (PLoS). - 1553-7404. ; 16:12
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Tidskriftsartikel (refereegranskat)abstract
- Deletions and duplications in mitochondrial DNA (mtDNA) cause mitochondrial disease and accumulate in conditions such as cancer and age-related disorders, but validated high-throughput methodology that can readily detect and discriminate between these two types of events is lacking. Here we establish a computational method, MitoSAlt, for accurate identification, quantification and visualization of mtDNA deletions and duplications from genomic sequencing data. Our method was tested on simulated sequencing reads and human patient samples with single deletions and duplications to verify its accuracy. Application to mouse models of mtDNA maintenance disease demonstrated the ability to detect deletions and duplications even at low levels of heteroplasmy. Author summary Deletions in the mitochondrial genome cause a wide variety of rare disorders, but are also linked to more common conditions such as neurodegeneration, diabetes type 2, and the normal ageing process. There is also a growing awareness that mtDNA duplications, which are also relevant for human disease, may be more common than previously thought. Despite their clinical importance, our current knowledge about the abundance, characteristics and diversity of mtDNA deletions and duplications is fragmented, and based to large extent on a limited view provided by traditional low-throughput analyses. Here, we describe a bioinformatics method, MitoSAlt, that can accurately map and classify mtDNA deletions and duplications using high-throughput sequencing. Application of this methodology to mouse models of mitochondrial deficiencies revealed a large number of duplications, suggesting that these may previously have been underestimated.
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| 10. |
- Dubois, Tobias, et al.
(författare)
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Test Quality Analysis and Improvement for an Embedded Asynchronous FIFO
- 2007
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Ingår i: Design, Automation & Test in Europe Conference & Exhibition, 2007. DATE '07. - Nice, France : IEEE. - 9783981080124 ; , s. 859-864
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Konferensbidrag (refereegranskat)abstract
- Embedded First-In First-Out (FIFO) memories are increasingly used in many IC designs. We have created a new full-custom embedded FIFO module with asynchronous read and write clocks, which is at least a factor two smaller and also faster than SRAM-based and standard-cell-based counterparts. The detection qualities of the FIFO test for both hard and weak resistive shorts and opens have been analyzed by an IFA-like method based on analog simulation. The defect coverage of the initial FIFO test for shorts in the bit-cell matrix has been improved by inclusion of an additional data background and low-voltage testing; for low-resistant shorts, 100% defect coverage is obtained. The defect coverage for opens has been improved by a new test procedure which includes waiting periods.
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