| 1. |
- Hammarsten, Ola, et al.
(författare)
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Troponin T percentiles from a random population sample, emergency room patients and patients with myocardial infarction
- 2012
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Ingår i: Clinical Chemistry. - : Oxford University Press (OUP). - 1530-8561 .- 0009-9147. ; 58:3, s. 628-637
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: High-sensitivity cardiac troponin T (cTnT) assays detect small clinically important myocardial infarctions (MI) but also yield higher rates of false-positive results owing to increased concentrations sometimes present in patients without MI. Better understanding is needed of factors influencing the 99th percentile of cTnT concentrations across populations and the frequency of changes in cTnT concentrations >20% often used in combination with increased cTnT concentrations for diagnosis of MI. METHODS: cTnT percentiles were determined by use of the Elecsys® hscTnT immunoassay (Modular® Analytics E170) in a random population sample, in emergency room (ER) patients, and in patients with non–ST-elevation MI (NSTEMI). Changes in cTnT concentrations were determined in hospitalized patients without MI. RESULTS: The 99th cTnT percentile in a random population sample (median age, 65 years) was 24 ng/L. In ER patients <65 years old without obvious conditions that increase cTnT, the 99th cTnT percentile was 12 ng/L with little age dependence, whereas in those >65 years old it was 82 ng/L and highly age dependent. In hospitalized patients without MI the 97.5th percentile for change in the cTnT concentration was 51%–67%. cTnT remained below the 99th percentile (12 ng/L) in 1% of patients with NSTEMI until 8.5 h after symptom onset and 6 h after ER arrival. CONCLUSIONS: Age >65 years was the dominant factor associated with increased cTnT in ER patients. This age association was more prominent in ER patients than in a random population sample. Changes in serial cTnT concentrations >20% were common in hospitalized patients without MI.
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| 2. |
- Larsson, Kerstin, 1963-, et al.
(författare)
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Discerning multiplicative and additive reasoning in co-variation problems
- 2015
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Ingår i: Proceeding of ICMI STUDY 23. - Macao : University of Macao. - 9789996510663 ; , s. 559-566
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Konferensbidrag (refereegranskat)abstract
- In this study of arithmetical reasoning, which extends earlier work, we explore what properties students, when working in pairs, discern in additive and multiplicative co-variation problems that help them to distinguish between problem types. Results showed that pairs who solved each problem appropriately discerned mathematically significant properties such as speed, starting time and distance. Pairs who over-used additive reasoning focused on the distance difference without considering speed. While speed is considered to be a difficult quantity, here it seems to help students distinguish between multiplicative and additive situations.
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| 3. |
- Larsson, Kerstin, 1963-, et al.
(författare)
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Students’ conceptualisation of multiplication as repeated addition or equal groups in relation to multi-digit and decimal numbers
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Annan publikation (övrigt vetenskapligt/konstnärligt)abstract
- Multiplicative understanding is essential for mathematics learning and is supported by models for multiplication, such as equal groups and rectangular area, different calculations and arithmetical properties, such as distributivity. We investigated two students’ multiplicative understanding through their connections between models for multiplication, calculations and arithmetical properties and how their connections changed during the school years when multiplication is extended to multi-digits and decimal numbers. The case studies were conducted by individual interviews over five semesters. The students did not connect calculations to models for multiplication, but showed a robust conceptualisation of multiplication as repeated addition or equal groups. This supported their utilisation of distributivity to multi-digits, but constrained their utilisation of commutativity and for one student to make sense of decimal multiplication.
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| 4. |
- Larsson, Kerstin, 1963-
(författare)
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Students' understandings of multiplication
- 2016
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Multiplicative reasoning permeates many mathematical topics, for example fractions and functions. Hence there is consensus on the importance of acquiring multiplicative reasoning. Multiplication is typically introduced as repeated addition, but when it is extended to include multi-digits and decimals a more general view of multiplication is required.There are conflicting reports in previous research concerning students’ understandings of multiplication. For example, repeated addition has been suggested both to support students’ understanding of calculations and as a hindrance to students’ conceptualisation of the two-dimensionality of multiplication. The relative difficulty of commutativity and distributivity is also debated, and there is a possible conflict in how multiplicative reasoning is described and assessed. These inconsistencies are addressed in a study with the aim of understanding more about students’ understandings of multiplication when it is expanded to comprise multi-digits and decimals.Understanding is perceived as connections between representations of different types of knowledge, linked together by reasoning. Especially connections between three components of multiplication were investigated; models for multiplication, calculations and arithmetical properties. Explicit reasoning made the connections observable and externalised mental representations.Twenty-two students were recurrently interviewed during five semesters in grades five to seven to find answers to the overarching research question: What do students’ responses to different forms of multiplicative tasks in the domain of multi-digits and decimals reveal about their understandings of multiplication? The students were invited to solve different forms of tasks during clinical interviews, both individually and in pairs. The tasks involved story telling to given multiplications, explicit explanations of multiplication, calculation problems including explanations and justifications for the calculations and evaluation of suggested calculation strategies. Additionally the students were given written word problems to solve.The students’ understandings of multiplication were robustly rooted in repeated addition or equally sized groups. This was beneficial for their understandings of calculations and distributivity, but hindered them from fluent use of commutativity and to conceptualise decimal multiplication. The robustness of their views might be explained by the introduction to multiplication, which typically is by repeated addition and modelled by equally sized groups. The robustness is discussed in relation to previous research and the dilemma that more general models for multiplication, such as rectangular area, are harder to conceptualise than models that are only susceptible to natural numbers.The study indicated that to evaluate and explain others’ calculation strategies elicited more reasoning and deeper mathematical thinking compared to evaluating and explaining calculations conducted by the students themselves. Furthermore, the different forms of tasks revealed various lines of reasoning and to get a richly composed picture of students’ multiplicative reasoning and understandings of multiplication, a wide variety of forms of tasks is suggested.
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| 5. |
- Larsson, Kerstin, 1963-, et al.
(författare)
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The ambiguous role of equal groups in students’ understanding of distributivity
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Annan publikation (övrigt vetenskapligt/konstnärligt)abstract
- Distributivity is considered to be essential for multiplicative understanding but difficult to learn. The difficulties may arise as overgeneralisations of addition strategies. Rectangular models emphasise the two-dimensionality of multiplication, separating it from addition and are suggested to support understanding of distributivity better compared to equal groups. Coincidently, studies report of students’ understanding of distributivity based on equal groups, leaving no consensus on equal groups’ suitability for understanding distributivity. In this paper we investigate how students can exploit equal groups to understand distributivity, by analysis of two students’ reasoning when they successfully explain distributivity construing the multiplication as heaps of sticks and bags of coins. The role of equal groups with respect to multiplicative understanding of distributivity is discussed in relation to previous ambiguous findings and to the extension of multiplication beyond integers, in which the equal groups model may be inappropriate.
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| 6. |
- Ariyawansa, Hiran A., et al.
(författare)
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Fungal diversity notes 111–252—taxonomic and phylogenetic contributions to fungal taxa
- 2015
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Ingår i: Fungal diversity. - : Springer Science and Business Media LLC. - 1560-2745 .- 1878-9129. ; 75, s. 27-274
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Tidskriftsartikel (refereegranskat)abstract
- This paper is a compilation of notes on 142 fungal taxa, including five new families, 20 new genera, and 100 new species, representing a wide taxonomic and geographic range. The new families, Ascocylindricaceae, Caryosporaceae and Wicklowiaceae (Ascomycota) are introduced based on their distinct lineages and unique morphology. The new Dothideomycete genera Pseudomassariosphaeria (Amniculicolaceae), Heracleicola, Neodidymella and P s e u d o m i c ros p h a e r i o p s i s ( D id y m e l l a c e a e ) , P s e u d o p i t h o m y c e s ( D i d y m o s p h a e r i a c e a e ) , Brunneoclavispora, Neolophiostoma and Sulcosporium (Halotthiaceae), Lophiohelichrysum (Lophiostomataceae), G a l l i i c o l a , Popul o c re s c e n t i a a nd Va g i c o l a (Phaeosphaeriaceae), Ascocylindrica (Ascocylindricaceae), E l o n g a t o p e d i c e l l a t a ( R o u s s o e l l a c e a e ) , Pseudoasteromassaria (Latoruaceae) and Pseudomonodictys (Macrodiplodiopsidaceae) are introduced. The newly described species of Dothideomycetes (Ascomycota) are Pseudomassariosphaeria bromicola (Amniculicolaceae), Flammeascoma lignicola (Anteagloniaceae), Ascocylindrica marina (Ascocylindricaceae) , Lembosia xyliae (Asterinaceae), Diplodia crataegicola and Diplodia galiicola ( B o t r yosphae r i a cea e ) , Caryospor a aquat i c a (Caryosporaceae), Heracleicola premilcurensis and Neodi dymell a thai landi cum (Didymellaceae) , Pseudopithomyces palmicola (Didymosphaeriaceae), Floricola viticola (Floricolaceae), Brunneoclavispora bambusae, Neolophiostoma pigmentatum and Sulcosporium thailandica (Halotthiaceae), Pseudoasteromassaria fagi (Latoruaceae), Keissleriella dactylidicola (Lentitheciaceae), Lophiohelichrysum helichrysi (Lophiostomataceae), Aquasubmersa japonica (Lophiotremataceae) , Pseudomonodictys tectonae (Macrodiplodiopsidaceae), Microthyrium buxicola and Tumidispora shoreae (Microthyriaceae), Alloleptosphaeria clematidis, Allophaeosphaer i a c y t i s i , Allophaeosphae r i a subcylindrospora, Dematiopleospora luzulae, Entodesmium artemisiae, Galiicola pseudophaeosphaeria, Loratospora(Basidiomycota) are introduced together with a new genus Neoantrodiella (Neoantrodiellaceae), here based on both morphology coupled with molecular data. In the class Agaricomycetes, Agaricus pseudolangei, Agaricus haematinus, Agaricus atrodiscus and Agaricus exilissimus (Agaricaceae) , Amanita m e l l e i a l b a , Amanita pseudosychnopyramis and Amanita subparvipantherina (Amanitaceae), Entoloma calabrum, Cora barbulata, Dictyonema gomezianum and Inocybe granulosa (Inocybaceae), Xerocomellus sarnarii (Boletaceae), Cantharellus eucalyptorum, Cantharellus nigrescens, Cantharellus tricolor and Cantharellus variabilicolor (Cantharellaceae), Cortinarius alboamarescens, Cortinarius brunneoalbus, Cortinarius ochroamarus, Cortinarius putorius and Cortinarius seidlii (Cortinariaceae), Hymenochaete micropora and Hymenochaete subporioides (Hymenochaetaceae), Xylodon ramicida (Schizoporaceae), Colospora andalasii (Polyporaceae), Russula guangxiensis and Russula hakkae (Russulaceae), Tremella dirinariae, Tremella graphidis and Tremella pyrenulae (Tremellaceae) are introduced. Four new combinations Neoantrodiella gypsea, Neoantrodiella thujae (Neoantrodiellaceae), Punctulariopsis cremeoalbida, Punctulariopsis efibulata (Punctulariaceae) are also introduced here for the division Basidiomycota. Furthermore Absidia caatinguensis, Absidia koreana and Gongronella koreana (Cunninghamellaceae), Mortierella pisiformis and Mortierella formosana (Mortierellaceae) are newly introduced in the Zygomycota, while Neocallimastix cameroonii and Piromyces irregularis (Neocallimastigaceae) ar e i n t roduced i n the Neocallimastigomycota. Reference specimens or changes in classification and notes are provided for Alternaria ethzedia, Cucurbitaria ephedricola, Austropleospora, Austropleospora archidendri, Byssosphaeria rhodomphala, Lophiostoma caulium, Pseudopithomyces maydicus, Massariosphaeria, Neomassariosphaeria and Pestalotiopsis montellica.
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| 7. |
- Bergström, Göran, 1964, et al.
(författare)
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Body weight at age 20 and in midlife is more important than weight gain for coronary atherosclerosis: Results from SCAPIS.
- 2023
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Ingår i: Atherosclerosis. - : Elsevier BV. - 1879-1484 .- 0021-9150. ; 373, s. 46-54
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Tidskriftsartikel (refereegranskat)abstract
- Elevated body weight in adolescence is associated with early cardiovascular disease, but whether this association is traceable to weight in early adulthood, weight in midlife or to weight gain is not known. The aim of this study is to assess the risk of midlife coronary atherosclerosis being associated with body weight at age 20, body weight in midlife and body weight change.We used data from 25,181 participants with no previous myocardial infarction or cardiac procedure in the Swedish CArdioPulmonary bioImage Study (SCAPIS, mean age 57 years, 51% women). Data on coronary atherosclerosis, self-reported body weight at age 20 and measured midlife weight were recorded together with potential confounders and mediators. Coronary atherosclerosis was assessed using coronary computed tomography angiography (CCTA) and expressed as segment involvement score (SIS).The probability of having coronary atherosclerosis was markedly higher with increasing weight at age 20 and with mid-life weight (p<0.001 for both sexes). However, weight increase from age 20 until mid-life was only modestly associated with coronary atherosclerosis. The association between weight gain and coronary atherosclerosis was mainly seen in men. However, no significant sex difference could be detected when adjusting for the 10-year delay in disease development in women.Similar in men and women, weight at age 20 and weight in midlife are strongly related to coronary atherosclerosis while weight increase from age 20 until midlife is only modestly related to coronary atherosclerosis.
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| 8. |
- Borg, Tomas, 1963-, et al.
(författare)
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Health-related quality of life and life satisfaction in patients following surgically treated pelvic ring fractures. A prospective observational study with two years follow-up
- 2010
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Ingår i: Injury. - : Elsevier. - 0020-1383 .- 1879-0267. ; 41:4, s. 400-404
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Pelvic ring fractures caused by high-energy trauma are severe injuries with well described radiological and clinical outcomes, whereas description from the patient's perspective is less well documented. The purpose of this study was to investigate patient-reported outcome following surgical treatment of pelvic fractures using quality of life instruments.METHODS: All 54 patients (28 male/26 female, ages 16-68) with pelvic fractures referred to our institution for surgical treatment 2003-2005 were prospectively included. The most common trauma was motor vehicle accident (44%). Additional injuries were seen in 74% and in 31% the ISS was >or=16. There were 31 B and 23 C type fractures. Patients were followed for two years using two validated questionnaires, SF-36 and LiSat-11, the latter an instrument consisting of 11 questions for evaluation of satisfaction with different aspects of life.RESULTS: 45 patients could be followed according to the study protocol for two years while 2 were untraceable and 1 died from unrelated causes. Of 6 nonresponders, 5 were unable due to psychiatric disorder. At two years pelvic fracture patients scored lower than the reference population in both physical and mental domains (SF-36). Highest mean score, 68, was in the domain Social Function (norm 89) while lowest mean score, 38, was in the domain Role Physical (norm 86). The mean score closest to the normative was for general health with 61 for patients and 78 for the normative group. In LiSat-11 pelvic fracture patients scored lower than the reference population in all areas. Satisfaction with life as a whole was 31% compared with 60% in the normative group.CONCLUSIONS: Two years after surgical treatment of pelvic ring fractures, patients reported substantially lower quality of life for both physical and mental domains, when compared with a reference population, even when radiological and clinical outcomes were considered favourable.
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| 9. |
- Flam, B, et al.
(författare)
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Authors' Response
- 2015
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Ingår i: Journal of intensive care medicine. - : SAGE Publications. - 1525-1489 .- 0885-0666. ; 52:1, s. 493-4
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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| 10. |
- Fors, Andreas, 1977, et al.
(författare)
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Person-centred care after acute coronary syndrome, from hospital to primary care - A randomised controlled trial
- 2015
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Ingår i: International Journal of Cardiology. - : Elsevier BV. - 0167-5273. ; 187, s. 693-699
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Tidskriftsartikel (refereegranskat)abstract
- AIM: To evaluate if person-centred care can improve self-efficacy and facilitate return to work or prior activity level in patients after an event of acute coronary syndrome. METHOD: 199 patients with acute coronary syndrome <75years were randomly assigned to person-centred care intervention or treatment as usual and followed for 6months. In the intervention group a person-centred care process was added to treatment as usual, emphasising the patient as a partner in care. Care was co-created in collaboration between patients, physicians, registered nurses and other health care professionals and documented in a health plan. A team-based partnership across three health care levels included transparent knowledge about the disease and medical state to achieve agreed goals during recovery. Main outcome measure was a composite score of changes in general self-efficacy >/=5units, return to work or prior activity level and re-hospitalisation or death. RESULTS: The composite score showed that more patients (22.3%, n=21) improved in the intervention group at 6months compared to the control group (9.5%, n=10) (odds ratio, 2.7; 95% confidence interval: 1.2-6.2; P=0.015). The effect was driven by improved self-efficacy >/=5units in the intervention group. Overall general self-efficacy improved significantly more in the intervention group compared with the control group (P=0.026). There was no difference between groups on re-hospitalisation or death, return to work or prior activity level. CONCLUSION: A person-centred care approach emphasising the partnership between patients and health care professionals throughout the care chain improves general self-efficacy without causing worsening clinical events.
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