| 1. |
- Botvinik-Nezer, Rotem, et al.
(författare)
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Variability in the analysis of a single neuroimaging dataset by many teams
- 2020
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Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 582, s. 84-88
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Tidskriftsartikel (refereegranskat)abstract
- Data analysis workflows in many scientific domains have become increasingly complex and flexible. Here we assess the effect of this flexibility on the results of functional magnetic resonance imaging by asking 70 independent teams to analyse the same dataset, testing the same 9 ex-ante hypotheses(1). The flexibility of analytical approaches is exemplified by the fact that no two teams chose identical workflows to analyse the data. This flexibility resulted in sizeable variation in the results of hypothesis tests, even for teams whose statistical maps were highly correlated at intermediate stages of the analysis pipeline. Variation in reported results was related to several aspects of analysis methodology. Notably, a meta-analytical approach that aggregated information across teams yielded a significant consensus in activated regions. Furthermore, prediction markets of researchers in the field revealed an overestimation of the likelihood of significant findings, even by researchers with direct knowledge of the dataset(2-5). Our findings show that analytical flexibility can have substantial effects on scientific conclusions, and identify factors that may be related to variability in the analysis of functional magnetic resonance imaging. The results emphasize the importance of validating and sharing complex analysis workflows, and demonstrate the need for performing and reporting multiple analyses of the same data. Potential approaches that could be used to mitigate issues related to analytical variability are discussed. The results obtained by seventy different teams analysing the same functional magnetic resonance imaging dataset show substantial variation, highlighting the influence of analytical choices and the importance of sharing workflows publicly and performing multiple analyses.
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| 2. |
- Coutu, Ashley N., et al.
(författare)
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Mapping the Elephants of the 19th Century East African Ivory Trade with a Multi-Isotope Approach
- 2016
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Ingår i: PLOS ONE. - : Public Library of Science (PLoS). - 1932-6203. ; 11:10
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Tidskriftsartikel (refereegranskat)abstract
- East African elephants have been hunted for their ivory for millennia but the nineteenth century witnessed strongly escalating demand from Europe and North America. It has been suggested that one consequence was that by the 1880s elephant herds along the coast had become scarce, and to meet demand, trade caravans trekked farther into interior regions of East Africa, extending the extraction frontier. The steady decimation of elephant populations coupled with the extension of trade networks have also been claimed to have triggered significant ecological and socio-economic changes that left lasting legacies across the region. To explore the feasibility of using an isotopic approach to uncover a 'moving frontier' of elephant extraction, we constructed a baseline isotope data set (delta C-13, delta N-15, delta O-18 and Sr-87/Sr-86) for historic East African elephants known to have come from three distinct regions (coastal, Rift Valley, and inland Lakes). Using the isotope results with other climate data and geographical mapping tools, it was possible to characterise elephants from different habitats across the region. This baseline data set was then used to provenance elephant ivory of unknown geographical provenance that was exported from East Africa during the late nineteenth and early twentieth centuries to determine its likely origin. This produced a better understanding of historic elephant geography in the region, and the data have the potential to be used to provenance older archaeological ivories, and to inform contemporary elephant conservation strategies.
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| 3. |
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| 4. |
- Holzkämper, Steffen, 1974-, et al.
(författare)
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Late Pleistocene stalagmite growth in Wolkberg Cave, South Africa
- 2009
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Ingår i: Earth and Planetary Science Letters. - Amsterdam : Elsevier. - 0012-821X .- 1385-013X. ; 282, s. 212-221
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Tidskriftsartikel (refereegranskat)abstract
- Little is known about the sequence of climate and environmental change in southern Africa during the last glacial period, in spite of the intimations from records, such as Antarctic ice cores and archaeological sites, that very marked changes took place which would have had profound effects on vegetation and animal distributions across the sub-continent. High-resolution, (semi-) continuous climate and environmental records can be extracted from suitable cave speleothems. Speleothems are reasonably abundant in southern Africa, but their occurrence is patchy in time and space and the records can be difficult to interpret. Here we report our assessment of the stalagmite W5 from Wolkberg Cave in the northeastern part of South Africa, as an archive for glacial-period climatic and environmental shifts. The cave is located at 1450 m asl, in the dolomitic limestones of the Transvaal System in an area currently dominated by C4 grass vegetation. Nine U/Th dates show growth from 58 to 46 ka, and a second brief phase ca. 40 ka, indicating that the available moisture was sufficient to allow speleothems to form. The δ18O and δ13C values along the growth axis show variability in the order of 2‰ for the former, while variability in the latter is characterized by a shift from values near − 2‰ in the older section to + 2‰ or more in the younger part. These high δ13C values are probably the combined result of CO2 degassing of the percolating soil water prior to the carbonate precipitation in the cave chamber, the increasing dominance of C4 over C3 vegetation, and the high percentage of aragonite towards the stalagmite's top. The retrieved data point towards increasingly drier and colder conditions during the growth period of the stalagmite. Furthermore, the high-frequency variations of δ18O values indicate the presence of short term climate oscillations that are probably linked to shifts of the Intertropical Convergence Zone.
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| 5. |
- Shipton, Ceri, et al.
(författare)
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78,000-year-old record of Middle and Later stone age innovation in an East African tropical forest
- 2018
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Ingår i: Nature Communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 9:1
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Tidskriftsartikel (refereegranskat)abstract
- The Middle to Later Stone Age transition in Africa has been debated as a significant shift in human technological, cultural, and cognitive evolution. However, the majority of research on this transition is currently focused on southern Africa due to a lack of long-term, stratified sites across much of the African continent. Here, we report a 78,000-year-long archeological record from Panga ya Saidi, a cave in the humid coastal forest of Kenya. Following a shift in toolkits ~67,000 years ago, novel symbolic and technological behaviors assemble in a non-unilinear manner. Against a backdrop of a persistent tropical forest-grassland ecotone, localized innovations better characterize the Late Pleistocene of this part of East Africa than alternative emphases on dramatic revolutions or migrations.
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