| 1. |
- Jung, Young-Eun, et al.
(författare)
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The Korean version of the Connor-Davidson Resilience Scale: An extended validation
- 2012
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Ingår i: Stress and Health. - : John Wiley & Sons. - 1532-3005 .- 1532-2998. ; 28:4, s. 319-326
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Tidskriftsartikel (refereegranskat)abstract
- The Connor–Davidson Resilience Scale (CD‐RISC) is a brief self‐rating questionnaire for measuring resilience. The aims of the present study were to describe the development of a Korean version of the CD‐RISC (K‐CD‐RISC) and to more firmly establish its psychometric properties in terms of reliability and validity. The participants consisted of a general population sample (n = 194) and psychiatric outpatients (n = 127) with non‐psychotic mood or anxiety disorders. The K‐CD‐RISC score means (standard deviation) were 65.9 (13.6) in the general population and 50.4 (20.5) in the psychiatric outpatients. The mean score of the general population was significantly higher than that of the psychiatric outpatients. Exploratory factor analysis revealed five factors, and the obtained factor structure was verified through confirmatory factor analysis. In the general population, the Cronbach's α coefficient of the K‐CD‐RISC was found to be 0.92. Greater resilience was found to be associated with less perceived stress, anxiety and depression and with higher levels of positive affect and purpose in life. Taken together, our findings suggest that the K‐CD‐RISC has good psychometric properties and is a valid and reliable tool for assessing resilience.
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| 2. |
- Kim, Hwan, et al.
(författare)
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Assessing procrastination in Korean : A study of the translation and validation of the Pure Procrastination Scale and a reexamination of the Irrational Procrastination Scale in a student and community sample
- 2020
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Ingår i: Cogent Psychology. - : Informa UK Limited. - 2331-1908. ; 7:1
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Tidskriftsartikel (refereegranskat)abstract
- Procrastination refers to voluntarily delay an intended course of action despite expecting that it might have negative consequences. It is usually assessed by self-reports, and the two most frequently used scales are the Pure Procrastination Scale (PPS) and the Irrational Procrastination Scale (IPS). The current study sought to investigate the reliability and validity of the two scales in Korean by translating the PPS from English and to reexamine a previous translation of the IPS. The aim is to promote further research on procrastination and to enhance a cross-cultural comprehension of the construct in different contexts. Hence, confirmatory factor analyses were conducted using data from 551 participants in a student and community sample. Convergent and discriminant validity, internal consistency, and test-retest reliability were also assessed. A three-factor solution exhibited an adequate fit for the PPS; decisional procrastination, implemental procrastination, and timeliness and promptness, although a one-factor solution with only the implemental part performed equally well. Meanwhile, a one-factor solution exhibited a reasonable fit for the IPS. Both scales correlated moderately with anxiety, r = .36-.37, depression, r = .37-.38, self-efficacy, r= .-34 to −.38, and quality of life, r = −.32 to −.34, all in the expected directions, but not so for perfectionism, r =.09-.10. Internal consistencies, Cronbach’s α = .93 (the PPS) and.85 (the IPS), and test-retest reliabilities (two weeks), r = .88 (the PPS) and.83 (the IPS), were good. The findings indicate that the Korean versions might be reliable and valid for researching procrastination.
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| 3. |
- Loth, Daan W, et al.
(författare)
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Genome-wide association analysis identifies six new loci associated with forced vital capacity
- 2014
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Ingår i: Nature Genetics. - : Springer Science and Business Media LLC. - 1061-4036 .- 1546-1718. ; 46, s. 669-677
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Tidskriftsartikel (refereegranskat)abstract
- Forced vital capacity (FVC), a spirometric measure of pulmonary function, reflects lung volume and is used to diagnose and monitor lung diseases. We performed genome-wide association study meta-analysis of FVC in 52,253 individuals from 26 studies and followed up the top associations in 32,917 additional individuals of European ancestry. We found six new regions associated at genome-wide significance (P < 5 × 10(-8)) with FVC in or near EFEMP1, BMP6, MIR129-2-HSD17B12, PRDM11, WWOX and KCNJ2. Two loci previously associated with spirometric measures (GSTCD and PTCH1) were related to FVC. Newly implicated regions were followed up in samples from African-American, Korean, Chinese and Hispanic individuals. We detected transcripts for all six newly implicated genes in human lung tissue. The new loci may inform mechanisms involved in lung development and the pathogenesis of restrictive lung disease.
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| 4. |
- Sakornsakolpat, Phuwanat, et al.
(författare)
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Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations
- 2019
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Ingår i: Nature Genetics. - : Springer Science and Business Media LLC. - 1061-4036 .- 1546-1718. ; 51:3, s. 494-505
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Tidskriftsartikel (refereegranskat)abstract
- Chronic obstructive pulmonary disease (COPD) is the leading cause of respiratory mortality worldwide. Genetic risk loci provide new insights into disease pathogenesis. We performed a genome-wide association study in 35,735 cases and 222,076 controls from the UK Biobank and additional studies from the International COPD Genetics Consortium. We identified 82 loci associated with P < 5 x 10-8; 47 of these were previously described in association with either COPD or population-based measures of lung function. Of the remaining 35 new loci, 13 were associated with lung function in 79,055 individuals from the SpiroMeta consortium. Using gene expression and regulation data, we identified functional enrichment of COPD risk loci in lung tissue, smooth muscle, and several lung cell types. We found 14 COPD loci shared with either asthma or pulmonary fibrosis. COPD genetic risk loci clustered into groups based on associations with quantitative imaging features and comorbidities. Our analyses provide further support for the genetic susceptibility and heterogeneity of COPD.
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