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Sökning: WFRF:(Lehtimäki Tomas)

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1.
  • Bentham, James, et al. (författare)
  • A century of trends in adult human height
  • 2016
  • Ingår i: eLIFE. - : eLife Sciences Publications Ltd. - 2050-084X. ; 5
  • Tidskriftsartikel (refereegranskat)abstract
    • Being taller is associated with enhanced longevity, and higher education and earnings. We reanalysed 1472 population-based studies, with measurement of height on more than 18.6 million participants to estimate mean height for people born between 1896 and 1996 in 200 countries. The largest gain in adult height over the past century has occurred in South Korean women and Iranian men, who became 20.2 cm (95% credible interval 17.5–22.7) and 16.5 cm (13.3– 19.7) taller, respectively. In contrast, there was little change in adult height in some sub-Saharan African countries and in South Asia over the century of analysis. The tallest people over these 100 years are men born in the Netherlands in the last quarter of 20th century, whose average heights surpassed 182.5 cm, and the shortest were women born in Guatemala in 1896 (140.3 cm; 135.8– 144.8). The height differential between the tallest and shortest populations was 19-20 cm a century ago, and has remained the same for women and increased for men a century later despite substantial changes in the ranking of countries.
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  • Fransson, Åsa, 1971, et al. (författare)
  • Characterization of fractured crystalline rock: two Swedish in situ field experiments
  • 2014
  • Ingår i: 1st International Discrete Fracture Network Engineering Conference, 20-22 oct 2014, Vancouver, Canada.
  • Konferensbidrag (refereegranskat)abstract
    • Construction of a nuclear waste repository requires information and an understanding of the fractured rock. The Swedish concept for nuclear waste deposition that is currently being developed by the Swedish Nuclear Fuel and Waste Management Co (SKB) includes a natural barrier in the form of crystalline rock, and engineered barriers in the form of bentonite and a copper canister. This paper aims to present two in situ field experiments: the first is the Large fractures experiment and the second is BRIE, the Bentonite Rock Interaction Experiment. Important issues include possible deformation (shearing) of fractures and deformation zones influencing the localization of canisters, and fluid flow, resulting in hydration of the bentonite. The aim of Large fractures is to further develop strategies and integrated investigation and modelling methodology for the identification and characterization of geological structures to ensure that (size) determination of large fractures or minor deformation zones to a greater extent can be based on real properties and to a lesser degree on a criterion related to the existence of a full perimeter fracture – tunnel intersection. BRIE is a field experiment which addresses the hydraulic interaction between the system components of compacted bentonite and the near-field host rock composed of hard and fractured bedrock. The above experiments are presented in terms of investigations performed to obtain discrete fracture descriptions. Grouting of fractures intersecting the investigation borehole of the Large fractures experiment was designed based on field data and a decrease in flow from above 200 liters/min to below 1 liter/min was achieved. The magnitude of the transmissivity of the fracture/deformation zone that was grouted indicates a large fracture size. This is also indicated by the ongoing integrated interpretation (geology, hydrogeology and geophysics). Results from BRIE show that hydration is uneven and is controlled by the main conductive fracture, highlighting the need for a relevant fracture description.
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4.
  • Ittner, Henrik, et al. (författare)
  • Design and control of the EDZ for a deep repository in crystalline rock
  • 2014
  • Konferensbidrag (refereegranskat)abstract
    • Knowledge about the Excavation Damaged Zone (EDZ) is essential for underground construction design, underground facility layout, work environment issues and analysis of post-closure safety for a final repository for nuclear waste. The EDZ is defined as the zone around a tunnel where the damage is not reversible. The EDZ can be caused by the excavation method as well as by the actual strength–stress conditions.SKB has chosen the Forsmark site for disposal of spent fuel. The site conditions include hard crystalline rock and fairly high stresses. However, analyzes prior to site selection found that the risk for stress induced development of an EDZ is limited. The aim of this paper is to outline the blast design concept and quality control measures to ensure that the excavation method fulfills the requirements. Strategies for blast design and QA/QC measures for tunnel excavation were applied during construction works for the Äspö HRL expansion 2012. This provided an opportunity to demonstrate methods for tunnel excavation and verify that requirements on minimizing the EDZ could be met during the construction of the planned Swedish final repository for spent fuel.
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5.
  • Sharifi Brojerdi, Fatemeh, et al. (författare)
  • High resolution seismic imaging at the planned tunnel entrance to the Forsmark repository for spent nuclear fuel, central Sweden
  • 2014
  • Ingår i: Near Surface Geophysics. - : Wiley. - 1569-4445 .- 1873-0604. ; 12, s. 709-719
  • Tidskriftsartikel (refereegranskat)abstract
    • The Swedish Nuclear Waste Management Company (SKB) plans to build a repository for storage of high-level radioactive spent nuclear fuel at the Forsmark site in central Sweden at a depth of about 470 m. The planned repository will cover an area of about 3.6 km(2) at this depth. Prior to beginning excavation and tunneling, some detailed geophysical surveys are being performed at the planned site. One of these was a refraction seismic survey to determine depth to bedrock in the vicinity of the planned access ramp. Two lines, each about 300 m long and spaced about 35 m apart, were acquired in August 2011. Since the bedrock topography is known to be highly variable, a close receiver (2 m) and source (6 m) spacing was required to map it. This close spacing allowed the data also to be treated as reflection seismic data and some adjustments to the acquisition procedure were made in the field with this in mind to aid in the later processing. The main adjustment was that seismic data were recorded on all geophone stations simultaneously. That is, as shots were fired along one line, data were recorded along both that line and the other one. Likewise, when shots were fired along the other line, data were recorded along that line and the first line. This adjustment allowed semi-3D coverage between the lines. Results from first break traveltime tomography along the lines indicate a depth to bedrock that is greater than that found from geotechnical observations along the lines. This discrepancy is attributed to the uppermost bedrock being highly fractured and having a velocity significantly below that expected from the intact bedrock deeper down. Reflection seismic processing of the data shows a reflection at about 20 ms (about 60 m). The reflection is interpreted to have a gentle northwesterly dip component to it. Comparison with core data in the area suggests that the reflection is from a thin (a few metres thick) fracture zone, although none of the boreholes actually penetrate the reflector where it is mapped by the seismic data. This fracture zone may be part of a larger fracture zone mapped by core drilling further to the east. The newly mapped reflector may be crossed by the ramp when excavation begins. Further seismic surveying towards the west is required to verify if this will be the case.
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6.
  • Zhou, Bin, et al. (författare)
  • Worldwide trends in diabetes since 1980: A pooled analysis of 751 population-based studies with 4.4 million participants
  • 2016
  • Ingår i: The Lancet. - : Elsevier B.V.. - 0140-6736 .- 1474-547X. ; 387:10027, s. 1513-1530
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: One of the global targets for non-communicable diseases is to halt, by 2025, the rise in the age standardised adult prevalence of diabetes at its 2010 levels. We aimed to estimate worldwide trends in diabetes, how likely it is for countries to achieve the global target, and how changes in prevalence, together with population growth and ageing, are aff ecting the number of adults with diabetes.Methods: We pooled data from population-based studies that had collected data on diabetes through measurement of its biomarkers. We used a Bayesian hierarchical model to estimate trends in diabetes prevalence-defined as fasting plasma glucose of 7.0 mmol/L or higher, or history of diagnosis with diabetes, or use of insulin or oral hypoglycaemic drugs-in 200 countries and territories in 21 regions, by sex and from 1980 to 2014. We also calculated the posterior probability of meeting the global diabetes target if post-2000 trends continue.Findings: We used data from 751 studies including 4372000 adults from 146 of the 200 countries we make estimates for. Global age-standardised diabetes prevalence increased from 4.3% (95% credible interval 2.4-17.0) in 1980 to 9.0% (7.2-11.1) in 2014 in men, and from 5.0% (2.9-7.9) to 7.9% (6.4-9.7) in women. The number of adults with diabetes in the world increased from 108 million in 1980 to 422 million in 2014 (28.5% due to the rise in prevalence, 39.7% due to population growth and ageing, and 31.8% due to interaction of these two factors). Age-standardised adult diabetes prevalence in 2014 was lowest in northwestern Europe, and highest in Polynesia and Micronesia, at nearly 25%, followed by Melanesia and the Middle East and north Africa. Between 1980 and 2014 there was little change in age-standardised diabetes prevalence in adult women in continental western Europe, although crude prevalence rose because of ageing of the population. By contrast, age-standardised adult prevalence rose by 15 percentage points in men and women in Polynesia and Micronesia. In 2014, American Samoa had the highest national prevalence of diabetes (>30% in both sexes), with age-standardised adult prevalence also higher than 25% in some other islands in Polynesia and Micronesia. If post-2000 trends continue, the probability of meeting the global target of halting the rise in the prevalence of diabetes by 2025 at the 2010 level worldwide is lower than 1% for men and is 1% for women. Only nine countries for men and 29 countries for women, mostly in western Europe, have a 50% or higher probability of meeting the global target.Interpretation: Since 1980, age-standardised diabetes prevalence in adults has increased, or at best remained unchanged, in every country. Together with population growth and ageing, this rise has led to a near quadrupling of the number of adults with diabetes worldwide. The burden of diabetes, both in terms of prevalence and number of adults aff ected, has increased faster in low-income and middle-income countries than in high-income countries.
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