| 1. |
- Chen, Anqi, et al.
(författare)
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Highly Sensitive Graphene Oxide-based Fabry-Perot Low-frequency Acoustic Sensor With Low-coherence Polarized Demodulation Using Three-step Phase-Shifting Arctan Algorithms
- 2024
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Ingår i: Journal of Lightwave Technology. - 0733-8724 .- 1558-2213. ; In Press
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Tidskriftsartikel (refereegranskat)abstract
- Developing low-frequency acoustic senor with high sensitivity is crucial for diverse applications, ranging from seismic monitoring, military operations, to pipeline surveillance. Here, we have proposed a high-sensitivity graphene oxide (GO)-based Fabry-Perot low-frequency sensor, in which a 170 nm thick, large-area and uniformly GO film was prepared by a vacuum filtration method. To enhance the accuracy and stability of the sensor, a low-coherence interference system based on birefringent crystal blocks was designed utilizing a three-step phase-shifting arctangent algorithm. Our sensor exhibited a sensitivity of -93.48 dB re 1 rad/μPa at 6-60 Hz with a fluctuation of 0.6 dB. The minimum detectable pressure of the sensor was measured at 0.37 μPa/Hz1/2 @20 Hz with a signal to noise ratio of 135.41 dB. Overall, this sensor offers simplicity in preparation, high sensitivity, low detectable sound pressure, making it a significant asset for low-frequency acoustic applications.
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| 2. |
- Zhang, Tianji, et al.
(författare)
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In-depth characterization of 1,4-butanediol diglycidyl ether substituted hyaluronic acid hydrogels
- 2023
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Ingår i: Carbohydrate Polymers. - : Elsevier. - 0144-8617 .- 1879-1344. ; 307
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Tidskriftsartikel (refereegranskat)abstract
- BDDE substituted HA hydrogels remain the most commonly used HA product in the biomedical field. The physical and biochemical properties of the hydrogels are dependent on the degree of modification and substitution patterns/positions, thus, characterizing their fine structure is of great importance for quality assurance. In this study, we developed novel LC-MS methods for accurate determination of MoD as well as in-depth characterization of the linkage network. Fragments resulted from enzymatic depolymerization were resolved by a porous graphitic carbon column followed by online tandem-MS for determining the modification site/residue. With high-resolution separation, two types of previously unknown structures were detected in the cross-linked fragments of 2-B-2 and 4-B-2. Based on the feature of resistance to NaBH4 reduction, these structures contain a GlcNAc residue modified at OH1. This special sugar unit likely derived from reducing end of the native polysaccharide could be a signature to discriminate subtle batch to batch variations.
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| 3. |
- Middeldorp, Christel M., et al.
(författare)
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The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia : design, results and future prospects
- 2019
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Ingår i: European Journal of Epidemiology. - : Springer Science and Business Media LLC. - 0393-2990 .- 1573-7284. ; 34:3, s. 279-300
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Tidskriftsartikel (refereegranskat)abstract
- The impact of many unfavorable childhood traits or diseases, such as low birth weight and mental disorders, is not limited to childhood and adolescence, as they are also associated with poor outcomes in adulthood, such as cardiovascular disease. Insight into the genetic etiology of childhood and adolescent traits and disorders may therefore provide new perspectives, not only on how to improve wellbeing during childhood, but also how to prevent later adverse outcomes. To achieve the sample sizes required for genetic research, the Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia were established. The majority of the participating cohorts are longitudinal population-based samples, but other cohorts with data on early childhood phenotypes are also involved. Cohorts often have a broad focus and collect(ed) data on various somatic and psychiatric traits as well as environmental factors. Genetic variants have been successfully identified for multiple traits, for example, birth weight, atopic dermatitis, childhood BMI, allergic sensitization, and pubertal growth. Furthermore, the results have shown that genetic factors also partly underlie the association with adult traits. As sample sizes are still increasing, it is expected that future analyses will identify additional variants. This, in combination with the development of innovative statistical methods, will provide detailed insight on the mechanisms underlying the transition from childhood to adult disorders. Both consortia welcome new collaborations. Policies and contact details are available from the corresponding authors of this manuscript and/or the consortium websites.
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