| 1. |
- Ekblom Bak, Elin, 1981-, et al.
(författare)
-
Accelerometer derived physical activity patterns in 27.890 middle‐aged adults : The SCAPIS cohort study
- 2022
-
Ingår i: Scandinavian Journal of Medicine and Science in Sports. - : John Wiley & Sons. - 0905-7188 .- 1600-0838. ; 32:5, s. 866-880
-
Tidskriftsartikel (refereegranskat)abstract
- The present study aims to describe accelerometer-assessed physical activity (PA) patterns and fulfillment of PA recommendations in a large sample of middle-aged men and women, and to study differences between subgroups of socio-demographic, socio-economic, and lifestyle-related variables. A total of 27 890 (92.5% of total participants, 52% women, aged 50–64 years) middle-aged men and women with at least four days of valid hip-worn accelerometer data (Actigraph GT3X+, wGT3X+ and wGT3X-BT) from the Swedish CArdioPulmonary bioImage Study, SCAPIS, were included. In total, 54.5% of daily wear time was spent sedentary, 39.1% in low, 5.4% in moderate, and only 0.1% in vigorous PA. Male sex, higher education, low financial strain, born in Sweden, and sedentary/light working situation were related to higher sedentary time, but also higher levels of vigorous PA. High BMI and having multiple chronic diseases associated strongly with higher sedentary time and less time in all three PA intensities. All-year physically active commuters had an overall more active PA pattern. The proportion fulfilling current PA recommendations varied substantially (1.4% to 92.2%) depending on data handling procedures and definition used. Twenty-eight percent was defined as having an “at-risk” behavior, which included both high sedentary time and low vigorous PA. In this large population-based sample, a majority of time was spent sedentary and only a fraction in vigorous PA, with clinically important variations between subgroups. This study provides important reference material and emphasizes the importance of a comprehensive assessment of all aspects of the individual PA pattern in future research and clinical practice.
|
|
| 2. |
- Ahlström, A., et al.
(författare)
-
No major differences in perinatal and maternal outcomes between uninterrupted embryo culture in time-lapse system and conventional embryo culture
- 2023
-
Ingår i: Human Reproduction. - : Oxford University Press. - 0268-1161 .- 1460-2350. ; 38:12, s. 2400-2411
-
Tidskriftsartikel (refereegranskat)abstract
- STUDY QUESTION: Is embryo culture in a closed time-lapse system associated with any differences in perinatal and maternal outcomes in comparison to conventional culture and spontaneous conception?SUMMARY ANSWER: There were no significant differences between time-lapse and conventional embryo culture in preterm birth (PTB, <37 weeks), low birth weight (LBW, >2500 g) and hypertensive disorders of pregnancy for singleton deliveries, the primary outcomes of this study.WHAT IS KNOWN ALREADY: Evidence from prospective trials evaluating the safety of time-lapse incubation for clinical use show similar embryo development rates, implantation rates, and ongoing pregnancy and live birth rates when compared to conventional incubation. Few studies have investigated if uninterrupted culture can alter risks of adverse perinatal outcomes presently associated with IVF when compared to conventional culture and spontaneous conceptions.STUDY DESIGN, SIZE, DURATION: This study is a Swedish population-based retrospective registry study, including 7379 singleton deliveries after fresh embryo transfer between 2013 and 2018 from selected IVF clinics. Perinatal outcomes of singletons born from time-lapse-cultured embryos were compared to singletons from embryos cultured in conventional incubators and 71 300 singletons from spontaneous conceptions. Main perinatal outcomes included PTB and LBW. Main maternal outcomes included hypertensive disorders of pregnancy (pregnancy hypertension and preeclampsia).PARTICIPANTS/MATERIALS, SETTING, METHODS: From nine IVF clinics, 2683 singletons born after fresh embryo transfer in a time-lapse system were compared to 4696 singletons born after culture in a conventional incubator and 71 300 singletons born after spontaneous conception matched for year of birth, parity, and maternal age. Patient and treatment characteristics from IVF deliveries were cross-linked with the Swedish Medical Birth Register, Register of Birth Defects, National Patient Register and Statistics Sweden. Children born after sperm and oocyte donation cycles and after Preimplantation Genetic testing cycles were excluded. Odds ratio (OR) and adjusted OR were calculated, adjusting for relevant confounders.MAIN RESULTS AND THE ROLE OF CHANCE: In the adjusted analyses, no significant differences were found for risk of PTB (adjusted OR 1.11, 95% CI 0.87-1.41) and LBW (adjusted OR 0.86, 95% CI 0.66-1.14) or hypertensive disorders of pregnancy; preeclampsia and hypertension (adjusted OR 0.99, 95% CI 0.67-1.45 and adjusted OR 0.98, 95% CI 0.62-1.53, respectively) between time-lapse and conventional incubation systems. A significantly increased risk of PTB (adjusted OR 1.31, 95% CI 1.08-1.60) and LBW (adjusted OR 1.36, 95% CI 1.08-1.72) was found for singletons born after time-lapse incubation compared to singletons born after spontaneous conceptions. In addition, a lower risk for pregnancy hypertension (adjusted OR 0.72 95% CI 0.53-0.99) but no significant difference for preeclampsia (adjusted OR 0.87, 95% CI 0.68-1.12) was found compared to spontaneous conceptions. Subgroup analyses showed that some risks were related to the day of embryo transfer, with more adverse outcomes after blastocyst transfer in comparison to cleavage stage transfer.LIMITATIONS, REASONS FOR CAUTION: This study is retrospective in design and different clinical strategies may have been used to select specific patient groups for time-lapse versus conventional incubation. The number of patients is limited and larger datasets are required to obtain more precise estimates and adjust for possible effect of additional embryo culture variables.WIDER IMPLICATIONS OF THE FINDINGS: Embryo culture in time-lapse systems is not associated with major differences in perinatal and maternal outcomes, compared to conventional embryo culture, suggesting that this technology is an acceptable alternative for embryo incubation.
|
|
| 3. |
- Hagren Idevall, Karin, 1984-
(författare)
-
Språk och rasism : Privilegiering och diskriminering i offentlig, medierad interaktion
- 2016
-
Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- This PhD thesis concerns language and racism. The aim is to explore how racism is reproduced in interaction in public debates on immigration, integration and refugee policy. From a constructivist pragmatic perspective, language is considered as a practice that composes and makes sense of our social world and all the phenomena and individuals that we perceive in it. Racist discourses discriminate against and privilege people by categorising them according to notions of cultural, ethnical, racial, religious and national differences.The thesis has two main themes: 1) the linguistic reproduction of, and response to, racist discrimination and privileging in interaction, and 2) the role of language in various public arenas, and the norms and conditions for participation in these arenas. The thesis comprises five studies. Study I examines racist discourses and conditions for participation in an online newspaper comments section. Study II examines how the phrase “politically correct” is used and negotiated in the same comments section, and how its usage leads to the reproduction and normalisation of racism. Another comments section is the focus of Study III, in which discriminating and privileging categorisations of Muslims, Islam, Swedes and Sweden are analysed. Study IV examines an anti-racist forum on the social networking site Instagram. In the study, the reproduction of norms of whiteness is analysed, as well as power relations that are evoked, sustained and transformed in interaction. Finally, Study V is an analysis of linguistic, visual and material reproductions of political positions and racist discourses in a debate among party leaders on Swedish television.The thesis demonstrates how normalisation of racism is accomplished in interaction, and how reproduction of hierarchically structured difference and bigoted stereotypes are performed, and challenged, through language. The medium, combined with the user’s speech acts, set up the norms and conditions for participation, and for the discursive processes that reproduce the relations and structures of power.
|
|
| 4. |
- Kordopatis, Georges, et al.
(författare)
-
Automatic line selection for abundance determinations in large stellar spectroscopic surveys
- 2023
-
Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 674
-
Tidskriftsartikel (refereegranskat)abstract
- Context. Over the past few years, new multiplex spectrographs have emerged to observe several millions of stars. The optimisation of these instruments (w.r.t. their resolution or wavelength range), their associated surveys (choice of instrumental set-up), and their parameterisation pipelines require methods that estimate which wavelengths (or pixels) contain useful information. Aims. We propose a method that establishes the usefulness of an atomic spectral line, whereby usefulness is defined by the purity of the line and its detectability. We demonstrate two applications of our code: a) optimising an instrument by comparing the number of detected useful lines at a given wavelength range and resolution; and b) optimising the line list for a given set-up, in the sense of creating a golden subsample of the least-blended lines that are detectable at a range of signal-to-noise ratio values. Methods. The method compares pre-computed normalised synthetic stellar spectra containing all of the elements and molecules with spectra solely containing the lines of specific elements. Then, the flux ratios between the full spectrum and the element spectrum are computed to estimate the line purities. The method automatically identifies: (i) the line's central wavelength, (ii) its detectability based on its depth and a given signal-to-noise threshold, and (iii) its usefulness based on the purity ratio defined above. Results. We applied this method to compare the three WEAVE high-resolution set-ups (blue: 404-465 nm, green: 473-545 nm, red: 595-685 nm) and find that the green+red set-up both allows us to measure more elements and contains more numerous useful lines. However, there is a disparity in terms of which elements are detected over each of the set-ups that we have characterised. We also studied the performances of high-resolution (R similar to 20 000) and low-resolution (R similar to 6000) spectra covering the entire optical wavelength range. Assuming a purity threshold of 60%, we find that the high-resolution set-up contains a much wealthier selection of lines, for any of the considered elements; whereas the low-resolution set-up displays a 'loss' of 50% to 90% of the lines (depending on the nucleosynthetic channel considered), even when the signal-to-noise ratio is increased. Conclusions. The method presented here provides a vital diagnostic of where to focus to get the most out of a spectrograph. It is easy to implement for future instruments that have not yet determined their final configuration, as well as for pipelines that require line masks.
|
|
| 5. |
- Wang, Ella Xi, et al.
(författare)
-
3D NLTE Lithium abundances for late-type stars in GALAH DR3
- 2024
-
Ingår i: Monthly notices of the Royal Astronomical Society. - 0035-8711 .- 1365-2966. ; 528:3, s. 5394-5411
-
Tidskriftsartikel (refereegranskat)abstract
- Lithium’s susceptibility to burning in stellar interiors makes it an invaluable tracer for delineating the evolutionary pathways of stars, offering insights into the processes governing their development. Observationally, the complex Li production and depletion mechanisms in stars manifest themselves as Li plateaus, and as Li-enhanced and Li-depleted regions of the HR diagram. The Li-dip represents a narrow range in effective temperature close to the main-sequence turn-off, where stars have slightly super-solar masses and strongly depleted Li. To study the modification of Li through stellar evolution, we measure 3D non-local thermodynamic equilibrium (NLTE) Li abundance for 581 149 stars released in GALAH DR3. We describe a novel method that fits the observed spectra using a combination of 3D NLTE Li line profiles with blending metal-line strength that are optimized on a star-by-star basis. Furthermore, realistic errors are determined by a Monte Carlo nested sampling algorithm which samples the posterior distribution of the fitted spectral parameters. The method is validated by recovering parameters from a synthetic spectrum and comparing to 26 stars in the Hypatia catalogue. We find 228 613 Li detections, and 352 536 Li upper limits. Our abundance measurements are generally lower than GALAH DR3, with a mean difference of 0.23 dex. For the first time, we trace the evolution of Li-dip stars beyond the main sequence turn-off and up the subgiant branch. This is the first 3D NLTE analysis of Li applied to a large spectroscopic survey, and opens up a new era of precision analysis of abundances for large surveys.
|
|
| 6. |
- Worley, C. C., et al.
(författare)
-
The Gaia-ESO Survey : The DR5 analysis of the medium-resolution GIRAFFE and high-resolution UVES spectra of FGK-type stars
- 2024
-
Ingår i: Astronomy and Astrophysics. - 0004-6361 .- 1432-0746. ; 684
-
Tidskriftsartikel (refereegranskat)abstract
- The Gaia-ESO Survey is an European Southern Observatory (ESO) public spectroscopic survey that targeted 105 stars in the Milky Way covering the major populations of the disk, bulge and halo. The observations were made using FLAMES on the VLT obtaining both UVES high (R ~ 47 000) and GIRAFFE medium (R ~ 20 000) resolution spectra. The analysis of the Gaia-ESO spectra was the work of multiple analysis teams (nodes) within five working groups (WG). The homogenisation of the stellar parameters within WG11 (high resolution observations of FGK stars) and the homogenisation of the stellar parameters within WG10 (medium resolution observations of FGK stars) is described here. In both cases, the homogenisation was carried out using a Bayesian Inference method developed specifically for the Gaia-ESO Survey by WG11. The method was also used for the chemical abundance homogenisation within WG11, however, the WG10 chemical abundance data set was too sparsely populated so basic corrections for each node analysis were employed for the homogenisation instead. The WG10 homogenisation primarily used the cross-match of stars with WG11 as the reference set in both the stellar parameter and chemical abundance homogenisation. In this way the WG10 homogenised results have been placed directly onto the WG11 stellar parameter and chemical abundance scales. The reference set for the metal-poor end was sparse which limited the effectiveness of the homogenisation in that regime. For WG11, the total number of stars for which stellar parameters were derived was 6 231 with typical uncertainties for Teff, log g and [Fe/H] of 32 K, 0.05 and 0.05 respectively. One or more chemical abundances out of a possible 39 elements were derived for 6 188 of the stars. For WG10, the total number of stars for which stellar parameters were derived was 76 675 with typical uncertainties for Teff, log g and [Fe/H] of 64 K, 0.15 and 0.07 respectively. One or more chemical abundances out of a possible 30 elements were derived for 64177 of the stars.
|
|
