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Träfflista för sökning "WFRF:(Lindblom P) "

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1.	Fachal, L, et al. (author) Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes 2020 In: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 52:1, s. 56-73 Journal article (peer-reviewed)
2.	Jiang, X., et al. (author) Shared heritability and functional enrichment across six solid cancers 2019 In: Nature Communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 10 Journal article (peer-reviewed)abstract Quantifying the genetic correlation between cancers can provide important insights into the mechanisms driving cancer etiology. Using genome-wide association study summary statistics across six cancer types based on a total of 296,215 cases and 301,319 controls of European ancestry, here we estimate the pair-wise genetic correlations between breast, colorectal, head/neck, lung, ovary and prostate cancer, and between cancers and 38 other diseases. We observed statistically significant genetic correlations between lung and head/neck cancer (r(g) = 0.57, p = 4.6 x 10(-8)), breast and ovarian cancer (r(g) = 0.24, p = 7 x 10(-5)), breast and lung cancer (r(g) = 0.18, p = 1.5 x 10(-6)) and breast and colorectal cancer (r(g) = 0.15, p = 1.1 x 10(-4)). We also found that multiple cancers are genetically correlated with non-cancer traits including smoking, psychiatric diseases and metabolic characteristics. Functional enrichment analysis revealed a significant excess contribution of conserved and regulatory regions to cancer heritability. Our comprehensive analysis of cross-cancer heritability suggests that solid tumors arising across tissues share in part a common germline genetic basis.
3.	Mavaddat, N, et al. (author) Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes 2019 In: American journal of human genetics. - : Elsevier BV. - 1537-6605 .- 0002-9297. ; 104:1, s. 21-34 Journal article (peer-reviewed)
4.	Garcia-Closas, M, et al. (author) Genome-wide association studies identify four ER negative-specific breast cancer risk loci 2013 In: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 45:4, s. 392-398 Journal article (peer-reviewed)
5.	Milne, RL, et al. (author) Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer 2017 In: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 49:12, s. 1767-1778 Journal article (peer-reviewed)
6.	Michailidou, K, et al. (author) Association analysis identifies 65 new breast cancer risk loci 2017 In: Nature. - : Springer Science and Business Media LLC. - 1476-4687 .- 0028-0836. ; 551:7678, s. 92- Journal article (peer-reviewed)
7.	Sawyer, E, et al. (author) Genetic predisposition to in situ and invasive lobular carcinoma of the breast 2014 In: PLoS genetics. - : Public Library of Science (PLoS). - 1553-7404. ; 10:4, s. e1004285- Journal article (peer-reviewed)
8.	Yang, XR, et al. (author) Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies 2011 In: Journal of the National Cancer Institute. - : Oxford University Press (OUP). - 1460-2105 .- 0027-8874. ; 103:3, s. 250-263 Journal article (peer-reviewed)
9.	Zhan, HY, et al. (author) Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses 2020 In: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 52:6, s. 572- Journal article (peer-reviewed)
10.	Bojesen, SE, et al. (author) Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer 2013 In: Nature genetics. - New york : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 45:4, s. 371-384 Journal article (peer-reviewed)

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Result 1-10 of 341

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Type of publication: journal article (310); conference paper (22); reports (3); other publication (3); book chapter (2); doctoral thesis (1); show more...; show less...

Type of content: peer-reviewed (296); other academic/artistic (45)

Author/Editor: Lindblom, A (200); Chang-Claude, J (105); Easton, DF (102); Czene, K (98); Hopper, JL (98); Fasching, PA (97); show more...; Hall, P (95); Dunning, AM (94); Couch, FJ (93); Nevanlinna, H (91); Hamann, U (90); Southey, MC (88); Schmidt, MK (88); Mannermaa, A (88); Garcia-Closas, M (88); Andrulis, IL (86); Pharoah, PDP (86); Bolla, MK (85); Beckmann, MW (85); Chenevix-Trench, G (85); Cox, A (84); Dork, T (84); Margolin, S (83); Wang, Q. (82); Giles, GG (82); Bojesen, SE (81); Devilee, P (81); Brenner, H (80); Dennis, J (80); Lambrechts, D (80); Milne, RL (78); Jakubowska, A (78); Burwinkel, B (77); Benitez, J. (76); Lubinski, J (76); Brauch, H (75); Radice, P (75); Peterlongo, P (74); Tomlinson, I (74); Michailidou, K (71); Flyger, H (71); Anton-Culver, H (70); Haiman, CA (67); Winqvist, R (67); Shah, M (66); Guenel, P (65); Kosma, VM (65); Meindl, A (65); Schmutzler, RK (64); Le Marchand, L (63); show less...

University: Karolinska Institutet (284); Uppsala University (86); Lund University (60); Umeå University (31); University of Gothenburg (15); Linköping University (8); show more...; Linnaeus University (5); Royal Institute of Technology (4); Chalmers University of Technology (3); Örebro University (2); Luleå University of Technology (1); Stockholm University (1); Jönköping University (1); Mid Sweden University (1); Swedish University of Agricultural Sciences (1); show less...

Language: English (341)

Research subject (UKÄ/SCB): Medical and Health Sciences (108); Engineering and Technology (11); Natural sciences (7); Social Sciences (4); Humanities (1)

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