| 1. |
- Springett, Jane, 1952-, et al.
(författare)
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Annual report 2004
- 2005
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Rapport (övrigt vetenskapligt/konstnärligt)
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| 2. |
- Springett, Jane, et al.
(författare)
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Annual report 2004
- 2005
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Bok (övrigt vetenskapligt/konstnärligt)
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| 3. |
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| 5. |
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| 6. |
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| 7. |
- Ahlström, Karin
(författare)
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Managing broad responsibility together in a municipal company : Communication as prophylaxis
- 2024
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Municipal companies are important actors in the pursuit of the goals of Agenda 2030 and are often formally obliged by their owners to work towards achieving these goals, but without jeopardizing ongoing production and the delivery of vital public services. This has, however, shown to be challenging, and managers are often unsure how to develop new ways of organizing to meet such complex challenges and take on broad responsibility. What has been recognized is the importance of collaboration, which is a beneficial and distinct organizational form of its own that creates value greater than what individual organizations can do separately. Such ways of working are, however, hardly straightforward endeavours, since they usually involve members with contrasting goals and approaches, are inclined to fragmentation, and can sometimes even add to the challenges they set out to resolve. The aim of this thesis is to understand the practical challenges associated with collaborative efforts to manage broad responsibility in a municipal company. In response to this aim, responsible managing is studied both empirically and through a research literature review. The purpose of the literature review is to better understand the challenges of managing broad responsibility and what is currently being done to achieve the goals of Agenda 2030 at the municipal level. To understand how responsible managing is accomplished in practice, the enactment of responsible manging is empirically studied in a municipal company over a total of four years. Particularly, two cases have been studied using a participatory research approach: first, the case of a top management team managing responsibly together and second, the case of responsible managing in interorganizational collaboration in a municipal company. For both cases, a theoretical lens is used, resting on a social constructionist and processual-relational ontology, supported by practice-based studies in the communicative stream. This means that attention is focused on communication (both talk and text) in an approach that views responsible managing as a communicative practice, a form of emergent, relational, and situated practice and the means by which responsible managing emerges, is sustained, and transformed. The overall results show how situated communicative practices are influential for preventing the limitation of broad responsibility, fragmentation of the share responsibility, and the deprioritization of obligations over time. Based on this, a metaphor of dental prophylaxis is proposed. By conceptualizing responsible managing as a situated communicative practice and showing how responsible managing may be enacted, this thesis contributes theoretically to the field of organization and management.
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| 8. |
- Andersson, Lena, 1965-, et al.
(författare)
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Respiratory health and inflammatory markers : Exposure to respirable dust and quartz and chemical binders in Swedish iron foundries
- 2019
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Ingår i: PLOS ONE. - : PLOS. - 1932-6203. ; 14:11
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Tidskriftsartikel (refereegranskat)abstract
- PURPOSE: To study the relationship between respirable dust, quartz and chemical binders in Swedish iron foundries and respiratory symptoms, lung function (as forced expiratory volume FEV1 and vital capacity FVC), fraction of exhaled nitric oxide (FENO) and levels of club cell secretory protein 16 (CC16) and CRP.METHODS: Personal sampling of respirable dust and quartz was performed for 85 subjects in three Swedish iron foundries. Full shift sampling and examination were performed on the second or third day of a working week after a work free weekend, with additional sampling on the fourth or fifth day. Logistic, linear and mixed model analyses were performed including, gender, age, smoking, infections, sampling day, body mass index (BMI) and chemical binders as covariates.RESULTS: The adjusted average respirable quartz and dust concentrations were 0.038 and 0.66 mg/m3, respectively. Statistically significant increases in levels of CC16 were associated with exposure to chemical binders (p = 0.05; p = 0.01) in the regression analysis of quartz and respirable dust, respectively. Non-significant exposure-responses were identified for cumulative quartz and the symptoms asthma and breathlessness. For cumulative chemical years, non-significant exposure-response were observed for all but two symptoms. FENO also exhibited a non significant exposure-response for both quartz and respirable dust. No exposure-response was determined for FEV1 or FVC, CRP and respirable dust and quartz.CONCLUSIONS: Our findings suggest that early markers of pulmonary effect, such as increased levels of CC16 and FENO, are more strongly associated with chemical binder exposure than respirable quartz and dust in foundry environments.
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| 9. |
- Carlsson, Björn, 1958, et al.
(författare)
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Obese (ob) gene defects are rare in human obesity
- 1997
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Ingår i: Obesity Research. - 1071-7323 .- 1550-8528. ; 5:1, s. 30-5
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Tidskriftsartikel (refereegranskat)abstract
- Our knowledge of the role of the recently cloned ob-protein (leptin) in the regulation of body fat stores is largely derived from experiments performed in mice. Different mouse models exhibit abnormalities in ob-gene expression, with extreme overexpression in mice which lack bioactive ob-protein, have nonfunctional ob-receptors or hypothalamic lesions, and undetectable expression in mice with suggested defects in regulatory elements. The aim of this study is to examine if defects, corresponding to those in mice, exist in human obesity. Adipose tissue was obtained from 94 adult obese subjects and from six children who had developed obesity after surgery in the hypothalamic region. Total RNA was isolated and ob-gene expression was examined by reverse transcriptase-polymerase chain reaction (RT-PCR) and Northern blot. The coding region of the ob-gene was sequenced in both directions in the 94 obese adults. No mutations were detected in the coding region of the ob-gene and ob-gene expression was detectable in all subjects and none of the subjects had an extreme overexpression. There was no systematic increase in ob-expression in obese children with hypothalamic disease compared to their healthy brothers and sisters. These results show that severe abnormalities involving the ob-gene, analogous to those described in mouse models, are rare in human obesity. We therefore conclude that the cloning and subsequent analysis of the ob-gene has not provided information that can, by itself, explain the genetic component in the development of human obesity.
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| 10. |
- Carlsson, Björn, 1958, et al.
(författare)
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Total RNA and array-based expression monitoring.
- 2000
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Ingår i: Nature biotechnology. - : Springer Science and Business Media LLC. - 1087-0156 .- 1546-1696. ; 18:6
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Tidskriftsartikel (refereegranskat)
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