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Sökning: WFRF:(Lindh Lennart)

  • Resultat 1-10 av 43
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1.
  • 5th FPGAworld CONFERENCE Book 2008
  • 2008
  • Samlingsverk (redaktörskap) (övrigt vetenskapligt/konstnärligt)abstract
    • The FPGAworld Conference addresses aspects of digital and hardware/software system engineering on FPGA technology.  It is a discussion and network forum for students, researchers and engineers working on industrial and research projects, state-of-the-art investigations, development and applications.  The book contains some presentations; for more information see (www.fpgaworld.com/conference).
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2.
  • Andersson, Elin, 1975, et al. (författare)
  • Type-dependent E6/E7 mRNA expression of single and multiple high-risk human papillomavirus infections in cervical neoplasia.
  • 2012
  • Ingår i: Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology. - : Elsevier BV. - 1873-5967. ; 54:1, s. 61-5
  • Tidskriftsartikel (refereegranskat)abstract
    • Coinfection with multiple HPV types is common in cervical lesions, but the biological significance of the individual infections is difficult to establish. Expression of oncogenic E6/E7 HPV mRNA is correlated to risk of malignant progression, commercial assays for genotyping E6/E7 mRNA of all HR-HPV are lacking.
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3.
  • Andersson, Elin, 1975, et al. (författare)
  • Type-specific HPV E6/E7 mRNA detection by real-time PCR improves identification of cervical neoplasia.
  • 2011
  • Ingår i: Journal of clinical microbiology. - 1098-660X. ; 49:11, s. 3794-3799
  • Tidskriftsartikel (refereegranskat)abstract
    • DNA-based HPV assays show high sensitivity but poor specificity in detecting high-grade cervical lesions. Assays detecting mRNA of oncogenic E6/E7 show higher specificity, but lack either detection of all high-risk HPV genotypes or the capacity to specify the detected genotypes. Therefore, a real-time PCR assay detecting type-specific E6/E7 mRNA was developed and the clinical performance evaluated. 210 cervical LBC (liquid based cytology) samples from 204 women were analysed for HPV DNA and mRNA with the in house real-time PCR as well as PreTect HPV-Proofer. The sensitivity of real-time PCR mRNA-detection to detect histologically confirmed CIN2+ (cervical intraepithelial neoplasia grade 2 or higher) were 0.91, compared to 0.95 for DNA-analysis. The specificity was 0.68 compared to 0.38, and the positive predictive value (PPV) was higher for mRNA (0.67 vs 0.52) without any loss in negative predictive value (NPV). The sensitivity of the real-time PCR mRNA-test was somewhat higher than for PreTect HPV-Proofer (0.83 vs 0.75), when analysing for the same genotypes. The specificity was similar (0.76 vs 0.77). When analysing for mRNA of the eight most common genotypes in cervical cancer (HPV16, 18, 31, 33, 35, 45, 52, 58), the sensitivity to detect CIN2+ lesions was 0.87 and the specificity 0.74, with a PPV of 0.70. In conclusion, real-time PCR for detection of HPV E6/E7 mRNA transcripts can be a sensitive and specific tool in screening and investigation of cervical neoplasia. The composition of HPV-types in mRNA-testing needs to be further investigated to optimize sensitivity and specificity.
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7.
  • Bengtsson, Lars, 1963, et al. (författare)
  • LowLevel C programming for Designers
  • 2015
  • Bok (övrigt vetenskapligt/konstnärligt)abstract
    • This book is concerned with C programming from an embedded systems engieer's point of view. That inlcudes writing device drivers for hardware with limited resources in terms of available instruction and data memory. A 32-bit soft CPU is implemented on an FPGA and theory is illustrated by detailed examples and cases.
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8.
  • Bergström, Gunnar, et al. (författare)
  • Does sickness presenteeism have an impact on future general health?
  • 2009
  • Ingår i: International Archives of Occupational and Environmental Health. - Berlin : Springer. - 0340-0131 .- 1432-1246. ; 82:10, s. 1179-1190
  • Tidskriftsartikel (refereegranskat)abstract
    • PURPOSE: The primary aim of this prospective study was to investigate whether working despite illness, so called "sickness presenteeism", has an impact on the future general health of two different working populations during a follow-up period of 3 years.METHODS: The study was based on two bodies of data collected at a number of Swedish workplaces from 1999 to 2003. The first material comprised 6,901 employees from the public sector and the second 2,862 subjects from the private sector. A comprehensive survey was issued three times: at baseline, after 18 months and after 3 years. Apart from the explanatory variable sickness presenteeism, several potential confounders were considered. The outcome variable was good/excellent versus fair/poor self-reported health.RESULTS: Sickness presenteeism at baseline was consistently found to heighten the risk of fair/poor health at both the 18-month and 3-year follow ups even after adjusting for the detected confounders.CONCLUSIONS: To the best of the authors' knowledge, this study is the first to show that sickness presenteeism appears to be an independent risk factor for future fair/poor general health.
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9.
  • El Shobaki, Mohammed, et al. (författare)
  • A hardware and software monitor for high-level system-on-chip verification
  • 2001
  • Ingår i: Proceedings - International Symposium on Quality Electronic Design, ISQED. - 0769510256 ; , s. 56-61
  • Konferensbidrag (refereegranskat)abstract
    • Verification of today's Systems-on-Chip (SoC) occur at low abstraction-levels, typically at register-transfer level (RTL). As the complexity of SoC designs grows, it is increasingly important to move verification to higher abstraction levels. Hardware/software co-simulation is a step in this direction, but is not sufficient due to inaccurate processor models, and slow hardware simulation speeds. System level monitoring, commonly used for event-based software debugging, provides information about task scheduling events, inter-task communication and synchronisation, semaphores/resources, I/O interrupts, etc. We present MAMon, a monitoring system that can both monitor the logic-level and the system-level in single/multiprocessor SoCs. A small hardware probe-unit is integrated in the SoC design and connects via a parallel port link to a host-based monitoring tool environment. The probe-unit collects all events in the target system in runtime, and timestamps them with a resolution of J ps. The events are then stored in a database on the host for further processing. The paper will describe MAMon and how it works for software and hardware monitoring. The paper also describe how system-level monitoring can be achieved non-instrusively by using a hardware-based Real-Time Kernel. 
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10.
  • FPGAworld CONFERENCE2009 SEPTEMBER
  • 2009
  • Proceedings (redaktörskap) (övrigt vetenskapligt/konstnärligt)abstract
    • The FPGAworld Conference addresses aspects of digital and hardware/software system engineering on FPGA technology. It is a discussion and network forum for students, researchers and engineers working on industrial and research projects, state-of-the-art investigations, development and applications. The book contains some presentations; for more information see (www.fpgaworld.com/conference).
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