| 1. |
- Toksvig-Larsen, Søren, et al.
(författare)
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The Porous-Coated Anatomic Total Knee Experience. Special Emphasis on Complications and Wear
- 1996
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Ingår i: Journal of Arthroplasty. - 0883-5403. ; 1:11, s. 11-17
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Tidskriftsartikel (refereegranskat)abstract
- One hundred sixty knees in 141 patients with the Primary Porous-Coated Anatomic prosthesis (Howmedica, Rutherford, NJ) were evaluated after a follow-up period of 5.6 years (range, 1–10 years). One hundred six knees were in the latest follow-up evaluation, including clinical examination and a defined standing radiograph with a follow-up period of 6.3 years (range, 3–10 years). Survivorship analysis regarding the cumulative revision rate (including completion with a patellar component) was 0.88 at the 8-year and 0.84 at the 10-year follow-up examination. The clinical result was satisfying/good, with a mean Hospital for Special Surgery score of 83 (range, 39–97). Five percent had thinning greater than 30% of the tibial component. The wear was calculated to be 1.0 mm (range, 0–9 mm), including three revised tibial components with heavy wear. Excluding the revised cases, the wear was 0.7 mm.
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| 2. |
- Al Mukaimi, Ali, et al.
(författare)
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Knee Arthroplasty in Kuwait during 25 Years: A National Presentation and an International Review
- 2008
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Ingår i: Kuwait Medical Journal. - 0023-5776. ; 40:4, s. 269-275
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Forskningsöversikt (refereegranskat)abstract
- Since 1984, 577 knee arthroplasty operations were performed in Al Razi Orthopedic hospital in Kuwait. An increase in the number of these operations occurred during the last four years and in 2007 there were almost 100 knee arthroplasty operations performed. Six out of seven operated patients were female. The mean age at operation was 67 years for male and 62 years for female patients. The vast majority were of the total knee arthroplasty type. In Sweden, with a total population of almost 10 million people, 10,544 primary knee prosthesis were implanted during 2006. In Kuwait, there is no certain statistics regarding the actual number of knee arthroplasty operations as Kuwaiti patients are also operated in private hospitals within and outside the country. It is estimated that 200 - 300 knee arthroplasty operations are performed annually on Kuwaitis. In order to get better epidemiological data and in order to improve the quality assurance of Knee and Hip arthroplasty operations in Kuwait, we propose that a national register is organised. National registers are in use in many other countries. The main indication for a knee arthroplasty is to relieve knee pain and to improve knee function. The operation allows for an active life-style. An active lifestyle, with more walking, is an advantage not only for the knee, but also for the general health. It also helps to better control other diseases like diabetes and obesity. The use of knee arthroplasties in Kuwait is increasing and the outcome of the procedure is generally favorable. It is not an overstatement to say that a well functioning knee arthroplasty means an increased quality of the whole life.
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| 3. |
- Al Mukaimi, Ali, et al.
(författare)
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Osteoarthritis of the Knee: Review of Risk Factors and Treatment Programs with Special Reference to Evidence-Based Research
- 2011
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Ingår i: Kuwait Medical Journal. - 0023-5776. ; 43:3, s. 176-188
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Forskningsöversikt (refereegranskat)abstract
- Osteoarthritis is a widespread disease leading to physical disability affecting quality of life. It is primarily regarded as a cartilage disease but affect all tissues of a joint. Osteoarthritis can be regarded as an organ failure. Knee osteoarthritis is common in Kuwait, especially in women. The main symptoms are pain, stiffness and weakness affecting knee function. The diagnosis is made by history and clinical examination. A weight-bearing radiograph will fully establish the diagnosis. Many of the patients are also obese, diabetic, hypertensive or affected by other organ failures. The aim is to reduce knee pain and improve knee function which is also beneficial for the other diseases. Initially, we recommend self-management by information about knee osteoarthritis, daily exercise of any type which is pleasant for the individual like 'walking 10-30 minutes once or twice daily in order to induce light to moderate cartilage load. Further, regular muscle training to increase especially pelvis and lower leg strength and realistic programs to reduce weight is advised. Regular support by a primary care doctor, a physiotherapist or a coach is beneficial. The program is demanding, as it means a change of life-style. Different modalities of non-operative treatment are physiotherapy, pharmacological treatment by analgesics / NSAIDs / glucosamine and injection of steroids or hyaluronic acid. The effect of the pharmacological treatment programs vary. Often the outcome, by evidence based research, is low or at best moderate. If self-management and non-operative treatment fails and the symptoms are pronounced, surgery is an option. Knee prosthesis is the main alternative.
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| 4. |
- Ali, Abdulemir, et al.
(författare)
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Dissatisfied patients after total knee arthroplasty
- 2014
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Ingår i: Acta Orthopaedica. - : Medical Journals Sweden AB. - 1745-3674 .- 1745-3682. ; 85:3, s. 229-233
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Tidskriftsartikel (refereegranskat)abstract
- Background and purpose - In 2003, an enquiry by the Swedish Knee Arthroplasty Register (SKAR) 2-7 years after total knee arthroplasty (TKA) revealed patients who were dissatisfied with the outcome of their surgery but who had not been revised. 6 years later, we examined the dissatisfied patients in one Swedish county and a matched group of very satisfied patients. Patients and methods - 118 TKAs in 114 patients, all of whom had had their surgery between 1996 and 2001, were examined in 2009-2010. 55 patients (with 58 TKAs) had stated in 2003 that they were dissatisfied with their knees and 59 (with 60 TKAs) had stated that they were very satisfied with their knees. The patients were examined clinically and radiographically, and performed functional tests consisting of the 6-minute walk and chair-stand test. All the patients filled out a visual analog scale (VAS, 0-100 mm) regarding knee pain and also the Hospital and Anxiety and Depression scale (HAD). Results - Mean VAS score for knee pain differed by 30 mm in favor of the very satisfied group (p < 0.001). 23 of the 55 patients in the dissatisfied group and 6 of 59 patients in the very satisfied group suffered from anxiety and/or depression (p = 0.001). Mean range of motion was 11 degrees better in the very satisfied group (p < 0.001). The groups were similar with regard to clinical examination, physical performance testing, and radiography. Interpretation - The patients who reported poor response after TKA continued to be unhappy after 8-13 years, as demonstrated by VAS pain and HAD, despite the absence of a discernible objective reason for revision.
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| 5. |
- Ali, Abdulemir, et al.
(författare)
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Preoperative Anxiety and Depression Correlate With Dissatisfaction After Total Knee Arthroplasty : A Prospective Longitudinal Cohort Study of 186 Patients, With 4-Year Follow-Up
- 2017
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Ingår i: Journal of Arthroplasty. - : Elsevier BV. - 0883-5403. ; 32:3, s. 767-770
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: After more than 4 decades experience of total knee arthroplasty (TKA), there is still a group of patients who are not satisfied with the outcome. In spite of the improvement of many aspects around the procedure, for unexplainable reasons, patient dissatisfaction is still approximately the same. We conducted this study to analyze correlations between preoperative psychological aspects and dissatisfaction after TKA.METHODS: A total of 186 patients were operated with a primary TKA. Patients filled out the Hospital Anxiety and Depression Scale, Visual Analog Pain Scale (0-100), and Knee injury and Osteoarthritis Outcome Score preoperatively and 4 years postoperatively. Four years postoperatively, the patients also scored their satisfaction degree with the outcome of the surgery.RESULTS: Of 186 patients, 27 (15%) reported that they were dissatisfied or uncertain with the result of their TKA 4 years postoperatively. Sixteen of those 27 patients had reported anxiety/depression preoperatively compared with 11 of 159 (7%) in the satisfied or very satisfied groups. Patients with preoperative anxiety or depression had more than 6 times higher risk to be dissatisfied compared with patients with no anxiety or depression (P < .001). Patients with deep prosthetic infection had 3 times higher risk to be dissatisfied with the operation outcome (P = .03). Dissatisfied patients had 1-day longer hospital stay compared with the satisfied group (P < .001).CONCLUSION: Preoperative anxiety and/or depression is an import predictor for dissatisfaction after TKA. Psychological assessment and treatment preoperatively might improve degree of satisfaction.
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| 6. |
- Ali, Abdulemir, et al.
(författare)
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Similar patient-reported outcomes and performance after total knee arthroplasty with or without patellar resurfacing : A randomized study of 74 patients with 6 years of follow-up
- 2016
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Ingår i: Acta Orthopaedica. - : Informa UK Limited. - 1745-3674 .- 1745-3682. ; 87:3, s. 274-279
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Tidskriftsartikel (refereegranskat)abstract
- Background and purpose — Knee pain after total knee arthroplasty (TKA) is not uncommon. Patellar retention in TKA is one cause of postoperative knee pain, and may lead to secondary addition of a patellar component. Patellar resurfacing in TKA is controversial. Its use ranges from 2% to 90% worldwide. In this randomized study, we compared the outcome after patellar resurfacing and after no resurfacing. Patients and methods — We performed a prospective, randomized study of 74 patients with primary osteoarthritis who underwent a Triathlon CR TKA. The patients were randomized to either patellar resurfacing or no resurfacing. They filled out the VAS pain score and KOOS questionnaires preoperatively, and VAS pain, KOOS, and patient satisfaction 3, 12, and 72 months postoperatively. Physical performance tests were performed preoperatively and 3 months postoperatively. Results — We found similar scores for VAS pain, patient satisfaction, and KOOS 5 subscales at 3, 12, and 72 months postoperatively in the 2 groups. Physical performance tests 3 months postoperatively were also similar in the 2 groups. No secondary resurfacing was performed in the group with no resurfacing during the first 72 months Interpretation — Patellar resurfacing in primary Triathlon CR TKA is of no advantage regarding pain, physical performance, KOOS 5 subscales, or patient satisfaction compared to no resurfacing. None of the patients were reoperated with secondary addition of a patellar component within 6 years. According to these results, routine patellar resurfacing in primary Triathlon TKA appears to be unnecessary.
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| 7. |
- Aranda-Guillén, Maribel, et al.
(författare)
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A polygenic risk score to help discriminate primary adrenal insufficiency of different etiologies.
- 2023
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Ingår i: Journal of internal medicine. - : John Wiley & Sons. - 0954-6820 .- 1365-2796. ; 294:1, s. 96-109
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Tidskriftsartikel (refereegranskat)abstract
- Autoimmune Addison's disease (AAD) is the most common cause of primary adrenal insufficiency (PAI). Despite its exceptionally high heritability, tools to estimate disease susceptibility in individual patients are lacking. We hypothesized that polygenic risk score (PRS) for AAD could help investigate PAI pathogenesis in pediatric patients.We here constructed and evaluated a PRS for AAD in 1223 seropositive cases and 4097 controls. To test its clinical utility, we reevaluated 18 pediatric patients, whose whole genome we also sequenced. We next explored the individual PRS in more than 120 seronegative patients with idiopathic PAI.The genetic susceptibility to AAD-quantified using PRS-was on average 1.5 standard deviations (SD) higher in patients compared with healthy controls (p<2e-16), and 1.2 SD higher in the young patients compared with the old (p=3e-4). Using the novel PRS, we searched for pediatric patients with strikingly low AAD susceptibility and identified cases of monogenic PAI, previously misdiagnosed as AAD. By stratifying seronegative adult patients by autoimmune comorbidities and disease duration we could delineate subgroups of PRS suggesting various disease etiologies.The PRS performed well for case-control differentiation and susceptibility estimation in individual patients. Remarkably, a PRS for AAD holds promise as a means to detect disease etiologies other than autoimmunity.
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| 8. |
- Benjaminson, Carin, 1958-
(författare)
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Ungdomars erfarenheter av emotionell utsatthet under uppväxten
- 2008
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- The purpose of this study is to describe and analyze the lifeworlds of youths subjected to emotional abuse during their childhoods. The following questions have been formulated: What experiences of emotional abuse do youths recount, and what do these experiences involve for the child? What picture of their encounter with the surrounding society do these youths provide, such as, for example, meetings with those close to them and with people at school, and what do these meetings involve for the child? What feelings have characterized their childhoods, and what consequences do these feelings have for the children’s lives and their transitions to adulthood? This study employs a qualitative lifeworld approach. Sixteen youths, 18 year olds have been identified through essays about their childhoods and thereafter have been interviewed about that period of their lives. The youths’ accounts of their emotional abuse depict a constant unpredictability, a lack of closeness, a lack of interest and engagement as well as criticism and abuse. This leads to a feeling among the youth of alienation from their families. The youth describe themselves as pro-active individuals and they experience the world around them as a passive and non-supportive adult world. The youths’ lives and their transitions into adulthood are characterized by feelings of socio-emotional insecurity and an existential loneliness but also a compensatory vitality. The need for emotional support in school so that these youth will be able to overcome emotional abuse and ontological insecurity is brought out. To be able to get through to emotionally abused children the school environment must generally be more relationship-oriented.
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| 9. |
- Björkvall, Anders, et al.
(författare)
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Connecting analogue and digital literacy practices? : On uses and semiotic potentials of digital pencils in Swedish middle school and high school
- 2023
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Ingår i: The 11th International Conference on Multimodality: Desiging Futures. - London : University College London. ; , s. 30-30
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Konferensbidrag (refereegranskat)abstract
- A dichotomization of the resources used for contemporary teaching, learning, and meaningmaking may result in a simplified division of such processes as either ‘digital’ or ‘analogue’. Our presentation addresses this dichotomy, and our understanding of semiotic technologies more broadly, by analyzing the potential of the digital pencil for connecting ‘analogue’ meaning-making to ‘digital’ meaning-making in the subject of Swedish in middle school and high school. Based on data from two pilot studies, each carried out for two months, our analysis focuses on how digital pencils can be used as tools for multimodal text creation in ways that draw on how this is typically done in analogue genres. This way, the analysis will provide knowledge of the semiotic potentials, affordances and actual uses of digital pencils in school, something which is lacking in previous research, with the exception of a few recent studies (e.g. Riche et al., 2017). Two main results stand out. First, digital pencils can actually be effectively used to draw on analogue literacy practices in the classroom. Second, digital pencils have other affordances (Lindstrand, 2022) than just functioning as “digital ink”: they are multifunctional in the sense that they can be used as tools for an array of multimodal tasks that analogue pencils cannot. Thus, the analysis concludes that not only can digital pencils be used to resemiotize analogue practices, but they also afford new ways of creating texts.
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| 10. |
- Blomstermo, Anders, et al.
(författare)
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The perceived usefulness of network experiential knowledge in the internationalizing firm
- 2004
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Ingår i: Journal of International Management. - : Elsevier. - 1075-4253 .- 1873-0620 .- 0813-0183. ; 10, s. 355-373
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Tidskriftsartikel (refereegranskat)abstract
- Because networks are a growing mode of doing business, internationalizing firms need to understand how they can use experiential knowledge of networks. In the context of organizational learning theory, we discuss in this article the perceived usefulness of network experiential knowledge, its antecedents, and its performance effects in the internationalization process of firms. A LISREL analysis of 256 firms found that more perceived usefulness of network experiential knowledge has a performance enhancing effect. Preceding the perceived usefulness of network experiential knowledge is internationalization experiential knowledge. In-depth study of interaction effects found that firms that have diverse market experiences and that are in a new foreign expansion situation particularly find their network experiential knowledge useful. This implies that the internationalizing firm builds routines from diverse market experiences for the development of networks in the early stages of a specific new international business expansion.
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