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- de Man Lapidoth, Joakim
(författare)
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Binge eating and obesity treatment : prevalence, measurement and long-term outcome
- 2009
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Eating disorders and binge eating has repeatedly been shown to be common in surgical and behavioural weight loss treatments. Due to methodological variations and shortcomings in previous research, there is insufficient information about how eating disorders and binge eating are associated with outcome in weight loss treatments. There is therefore no consensus on how eating pathology should be adressed in weight loss treatments, which has led to large differences in the clinical practice. The main aim of this thesis was to address the issues of eating disorders and binge eating in weight loss treatments, and to investigate how binge eating is associated with long-term treatment outcome.
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- Ekelund, Ulf, et al.
(författare)
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Association of weight gain in infancy and early childhood with metabolic risk in young adults
- 2007
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Ingår i: Journal of Clinical Endocrinology and Metabolism. - : The Endocrine Society. - 0021-972X .- 1945-7197. ; 92:1, s. 98-103
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Tidskriftsartikel (refereegranskat)abstract
- CONTEXT: Early postnatal life has been suggested as an important window during which risks for long-term health may be influenced. OBJECTIVE: The aim of this study was to examine the independent associations between weight gain during infancy (0-6 months) and early childhood (3-6 yr) with components of the metabolic syndrome in young adults. DESIGN: This was a prospective cohort study (The Stockholm Weight Development Study). SETTING: The study was conducted in a general community. PARTICIPANTS: Subjects included 128 (54 males) singletons, followed from birth to 17 yr. MAIN OUTCOME MEASURE: None of these young adults met the full criteria for the metabolic syndrome. We therefore calculated a continuous clustered metabolic risk score by averaging the standardized values of the following components: waist circumference, blood pressure, fasting triglycerides, high-density lipoprotein cholesterol, glucose, and insulin level. RESULTS: Clustered metabolic risk at age 17 yr was predicted by weight gain during infancy (standardized beta = 0.16; P < 0.0001) but not during early childhood (standardized beta = 0.10; P = 0.23), adjusted for birth weight, gestational age, current height, maternal fat mass, and socioeconomic status at age 17 yr. Further adjustment for current fat mass and weight gain during childhood did not alter the significant association between infancy weight gain with the metabolic risk score (standardized beta = 0.20; P = 0.007). CONCLUSIONS: Rapid weight gain during infancy (0-6 months) but not during early childhood (3-6 yr) predicted clustered metabolic risk at age 17 yr. Early interventions to moderate rapid weight gain even at very young ages may help to reduce adult cardiovascular disease risks.
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- Gothefors, Dan, et al.
(författare)
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Swedish clinical guidelines-Prevention and management of metabolic risk in patients with severe psychiatric disorders
- 2010
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Ingår i: Nordic Journal of Psychiatry. - : Informa UK Limited. - 1502-4725 .- 0803-9488. ; 64:5, s. 294-302
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Tidskriftsartikel (refereegranskat)abstract
- Individuals with severe psychiatric disorders are more likely than the population at large to develop metabolic derangements such as overweight and diabetes. Cardiovascular disease is also more frequently seen in this group. Contributing factors may include inappropriate diet or lack of physical activity, but antipsychotic medication may also play a role. Seven Swedish specialist medical societies have collaborated in formulating a set of concise clinically applicable guidelines-reproduced here in modified form-for the prevention and management of metabolic risk in this patient group. The importance of implementation is emphasized.
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- Linné, Yvonne
(författare)
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Factors affecting weight development after pregnancy : the SPAWN (Stockholm Pregnancy And Women's Nutrition) study
- 2002
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Obesity is a growing problem all over the world. For some women pregnancy is a trigger event for developing overweight or obesity and 73% of female patients at the Obesity Unit indicated that they had retained more than 10 kg after each of their pregnancies. For this subgroup weight development after pregnancy was of crucial importance for their future health. The SPAWN (Stockholm Pregnancy And Women's Nutrition) study is a long-term followup study of women who delivered children in 1984-85 in Stockholm (n =2342). 1423 participants completed questionnaires which covered eating behaviour and exercise, demographic information including social situation and status and details of the pregnancy before, during and up to one year after pregnancy. Fifteen years later these women were invited to take part in the follow-up study (SPAWN). Anthropometric measurements and the same questionnaire data were collected on the 563 women who participated. Detailed drop-out analyses indicate that this subsample was representative. We have also monitored a group of women with gestational diabetes (GDM) and studied sweet food intake in women. Our main findings are: Both high weight gainers and high weight retainers had higher BMI values at 15 years of follow-up, although only 56% of the high weight gainers during pregnancy ended up as the high weight retainers one year after pregnancy. Weight retention at the end of the postpartum year, however, predicts future overweight. Contrary to popular belief and official recommendations, high BMI before pregnancy is not a predictor for weight retention. Women with overweight before pregnancy do not have a higher risk of postpartum weight retention than normal weight women. Women who are diagnosed with GDM have a considerably higher risk of developing type 2 diabetes mellitus later in life. More active strategies for future weight control and lifestyle advice after delivery might therefore be indicated for women with GDM. Our SPAWN data furthermore suggests that women with depressive traits have higher intakes of sweet foods, suggesting a link between mood regulation and consumption of in particular chocolate. Salivary counts of mutans streptococci and lactobacilli are simple, cheap and chair-side tests known to mirror the consumption of fermented carbohydrates and may thus be used as an objective indicator of the sweet food intake in dietary surveys.
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- Molin, M., et al.
(författare)
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Case management at an outpatient unit for severe and enduring eating disorder patients at Stockholm Centre for Eating Disorders : a study protocol
- 2016
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Ingår i: International Journal of Eating Disorders. - London, United Kingdom : BioMed Central. - 0276-3478 .- 1098-108X .- 2050-2974. ; 4
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Tidskriftsartikel (refereegranskat)abstract
- Background: Patients with severe and enduring eating disorders (SEED) are seriously ill and have a low quality of life. Case management (CM), originally developed for adult patients with severe mental disabilities, has been shown to enhance social functioning and improve quality of life, while reducing the number and length of hospitalizations. In 2014, a special unit based on CM, for patients with SEED (the Eira unit) was started at Stockholm Centre for Eating Disorders, Sweden.Method/Design: This study aims to investigate if CM can improve SEED patients' quality of life, and reduce their eating disorder symptoms as well as their health care consumption. Methods for data collection are a semi-structured diagnostic interview, self-report questionnaires, and a qualitative interview. The diagnostic interview and the self-report assessments will be done at start of treatment and at follow-ups after 1, 2, and 3years. The qualitative interview will be conducted 1 year after start of treatment. The study is approved by the ethical review board in Stockholm in compliance with the Helsinki Declaration.Discussion: CM is a possible new contribution to the treatment methods for SEED. It does not aim at remission, but rather to accept life as it is, and to enhance quality of life in the presence of the ED. This study will investigate the potential benefits of this novel intervention in a special unit for SEED patients.Trail Registration: Clinicaltrials.gov Id: NCT02897622.
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- Neovius, Martin, et al.
(författare)
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Adiposity measures as indicators of metabolic risk factors in adolescents
- 2009
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Ingår i: Obesity Facts. - : S. Karger AG. - 1662-4025 .- 1662-4033. ; 2:5, s. 294-301
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Tidskriftsartikel (refereegranskat)abstract
- Aim: To examine the relation between adiposity assessment methods (percentage body fat (%BF), BMI, and waist circumference (WC)) and individual metabolic risk factors (f-insulin, HDL cholesterol, triglycerides) and a combined measure of metabolic risk. Methods: Cross-sectional study of 300 males (BMI 20.8 +/- 3.0 kg/m(2)) and females (BMI 21.3 +/- 2.9 kg/m(2)) 17 years of age. F-insulin and components of the metabolic syndrome defined by the International Diabetes Federation (IDF) were used as metabolic risk indicators, with samples stratified into BMI, %BF, and WC groups, respectively. Diagnostic accuracy was expressed as the area under the ROC curve (AUC). Results: In males, diagnostic accuracy for HDL and f-insulin was poor to fair for BMI (AUC 0.70, p = 0.001; 0.60, p = 0.22), WC (0.68, p = 0.003; 0.63, p = 0.11), and %BF (0.65, p = 0.009; 0.66, p = 0.04). The diagnostic accuracy for triglycerides was greater for all three measures (BMI 0.92, WC 0.95, %BF 0.87; all p < 0.001). For females, neither test performed better than chance for f-insulin and HDL, and only %BF performed better than chance for triglycerides (0.65, p = 0.08). All three measures exhibited higher accuracy for presence of >= 2 metabolic risk factors (AUCs 0.76-0.91, p < 0.001) in both sexes. Conclusion: %BF was not superior to BMI and WC for detecting metabolic risk in the general adolescent population.
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- van der Mark, Marianne, et al.
(författare)
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Older Members Perform Better in an Internet-Based Behavioral Weight Loss Program Compared to Younger Members
- 2009
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Ingår i: Obesity Facts. - Basel : S. Karger. - 1662-4025 .- 1662-4033. ; 2:2, s. 74-79
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Tidskriftsartikel (refereegranskat)abstract
- Background: New technology offers increased opportunities for weight control. However, it is not clear whether older people with less computer training can make use of this tool. Our objective was to examine how members above the age of 65 years performed in an internet-based behavioral weight loss program, compared to younger members. Methods: Data from members (n = 23,233) of an internet-based behavioral weight loss program were analyzed. We restricted our study to active participants accessing the weight club, during a 6-month period (n = 4,440). The number of logins, food intake, and weight records were examined. Participants were divided into age tertiles separately for men and women. The oldest tertile was further subdivided into two groups: above and below the age of 65 years. Results: Participants aged 65 or older were more likely to remain active in the weight club for at least 6 months compared to younger age groups. They had the highest frequency of recordings of food intake and current weight. Among women, those older than 65 years had on average the highest percentage of weight loss (5.6 kg, 6.8%). Men above 65 years of age had the highest number of logins, on average 161 times during the 6-month period. Conclusion: Older participants are performing equally well or even better in an internet-based behavioral weight loss program than younger participants. Internet-based programs could be a promising and attractive option for older adults requiring assistance in losing weight. © 2009 S. Karger AG, Basel.
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- Vågstrand, Karin, et al.
(författare)
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Associations between salivary bacteria and reported sugar intake and their relationship with body mass index in women and their adolescent children.
- 2008
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Ingår i: Public Health Nutrition. - 1368-9800. ; 11:4, s. 341-8
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVE: To study associations between reported sugar intake and salivary bacteria (mutans streptococci, MS and lactobacilli, LB), and sugar intake in relation to body mass index (BMI), in women and adolescents. DESIGN: Cross-sectional study. Habitual dietary intake was reported in a questionnaire and whole saliva samples were collected and cultivated. SETTING: Stockholm, Sweden. SUBJECTS: Four hundred and fourteen mothers and their 16-year-old children (57% girls). RESULTS: Reported total sugar intake was significantly associated with LB in mothers (P = 0.001), but not in daughters and sons (P = 0.03 for mother-son interaction). When excluding lactose, the associations with LB and MS were significant in daughters (P = 0.032 and 0.005, respectively). High BMI and sugar intake from milk were independently associated with MS counts in mothers in a multiple regression model (R2 = 0.053). In daughters, sugar from beverages, candies/chocolates and fruits were all independently associated with MS counts (R2 = 0.074), whereas in sons, only mothers' MS counts were associated (R2 = 0.084). High BMI, low intake from cooked meals and high intake of candies/chocolates were all independently associated with LB in mothers (R2 = 0.076), while, except for candies/chocolates in daughters, no significant associations were found in children. BMI was significantly associated with bacteria counts in both mothers and children, whereas reported sugar intake was not.ConclusionThe associations between reported sugar intake and bacteria were generally weak. In mothers and daughters, some significant associations were found, but not in sons. Bacteria counts, but not reported sugar intake, were positively associated with BMI.
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