| 1. |
- Aad, G., et al.
(författare)
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- 2011
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swepub:Mat__t (refereegranskat)
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| 2. |
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| 3. |
- Krmar, R T, et al.
(författare)
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Acute renal failure in dense deposit disease: complete recovery after combination therapy with immunosuppressant and plasma exchange.
- 2011
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Ingår i: Clinical Nephrology. - 0301-0430. ; 75:S1, s. 4-10
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Tidskriftsartikel (refereegranskat)abstract
- We describe the clinical course of a female adolescent who was followed because of isolated microhematuria and hypocomplementemia before admission to hospital with a sudden onset of acute renal failure. At presentation, she exhibited complement consumption through the complement alternative pathway (AP) while other serologic tests were negative. Renal biopsy revealed dense deposit disease (DDD) with a crescentic pattern. Intravenous methylprednisolone, followed by plasma exchange (PE), and intravenous cyclophosphamide pulses were started shortly after admission. C3NeF and anti-factor H antibody tests were negative. Serum factor H and I levels were normal as well as factor H activity. Screening for mutation in the factor H gene revealed the H402 allele variant. Clinical remission, defined as normalization in renal function and in the activity levels of the complement AP, was noted at one month post-presentation and throughout the follow-up. A repeat renal biopsy showed the disappearance of crescent formation, whereas electron microscopy revealed no regression in dense transformation of the lamina densa. In summary, our patient was successfully treated with immunosuppressant and PE. The absence of known factors associated with DDD suggests that, in this particular case, other regulatory mechanisms of complement AP might have been involved in the disease process.
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| 4. |
- Mills, James A., et al.
(författare)
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Archiving Primary Data : Solutions for Long-Term Studies
- 2015
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Ingår i: Trends in Ecology & Evolution. - : Elsevier BV. - 0169-5347 .- 1872-8383. ; 30:10, s. 581-589
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Tidskriftsartikel (refereegranskat)abstract
- The recent trend for journals to require open access to primary data included in publications has been embraced by many biologists, but has caused apprehension amongst researchers engaged in long-term ecological and evolutionary studies. A worldwide survey of 73 principal investigators (PIs) with long-term studies revealed positive attitudes towards sharing data with the agreement or involvement of the PI, and 93% of PIs have historically shared data. Only 8% were in favor of uncontrolled, open access to primary data while 63% expressed serious concern. We present here their viewpoint on an issue that can have non-trivial scientific consequences. We discuss potential costs of public data archiving and provide possible solutions to meet the needs of journals and researchers.
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| 5. |
- Paciaroni, Megan, et al.
(författare)
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Single-shot two-dimensional ballistic imaging of the liquid core in an atomizing spray
- 2006
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Ingår i: Atomization and Sprays. - 1936-2684. ; 16:1, s. 51-69
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Tidskriftsartikel (refereegranskat)abstract
- We have developed a technique to image the near-field liquid core within an atomizing spray. To obtain high-fidelity images of the liquid core in such a spray has been very challenging up to this point. In this article, however, we describe the successful use of a time-gated ballistic imaging instrument to obtain high spatial resolution, single-shot images of the liquid core in an atomizing water spray. Time series of these images reveal a flow field undergoing turbulent primary breakup. One can also detect potential signatures of spatially periodic behavior, shedding of droplets from an intact core, and small voids that seem to appear and then coalesce with distance. We present images at six positions downstream of the jet exit and discuss our findings.
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| 9. |
- Dreyer, C, et al.
(författare)
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Raman scattering at 532 and 355 nm in atmospheric pressure propane/air flames, with and without liquid fuels
- 2004
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Ingår i: Applied Physics B. - : Springer Science and Business Media LLC. - 0946-2171 .- 1432-0649. ; 79:1, s. 121-130
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Tidskriftsartikel (refereegranskat)abstract
- We discuss an experimental investigation of Raman scattering spectroscopy in the vicinity of a simulated reacting liquid fuel spray. Spray flames are known to produce interference from droplet elastic scattering, laser-induced fluorescence, and laser-induced incandescence of soot. The goal in this work is to evaluate various experimental approaches to this challenging problem. We evaluate Raman scattering from both 532 and 355 nm beams (second and third harmonics of Nd : YAG), at various polarization orientations and over various lifetimes. We discuss tradeoffs between the various approaches and identify operating regimes in which such Raman measurements are possible. Perhaps the most compelling finding of this work is that the third harmonic of Nd : YAG holds more promise for measurement in high-pressure, combusting spray environments than has been previously thought.
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