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Sökning: WFRF:(Lippens L.)

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1.
  • Hendrix, A., et al. (författare)
  • Extracellular vesicle analysis
  • 2023
  • Ingår i: Nature Reviews Methods Primers. - 2662-8449. ; 3:1
  • Forskningsöversikt (refereegranskat)abstract
    • Cells release small, phospholipid membrane-enclosed particles, collectively referred to as extracellular vesicles (EVs), into their surroundings to enable intercellular communication. EVs have numerous functions in physiological and pathophysiological processes and show considerable promise for diagnostic and therapeutic applications. Technologies have rapidly evolved over the past two decades, providing a powerful, versatile toolset for preparing and characterizing EVs to facilitate research and translational efforts. However, considering the plethora of methods available, it is challenging to understand what makes one method more suited for a given experiment than another. The heterogeneity of EVs as well as the diversity in composition of their surroundings further add to this challenge. This Primer provides guidance for EV analysis across ecosystems, including accessible body- and environment-derived sources. We summarize the multi-step process of EV preparation, cover the guiding principles and considerations when performing and interpreting EV experiments, and reflect on the limitations and challenges in the fields of fundamental biology, biomarker development and therapeutic strategies. Extracellular vesicles (EVs) have vital functions and promise diagnostic and therapeutic applications. In this Primer, Hendrix and colleagues discuss tools for isolating and characterizing EVs obtained from various sources, including the body and the environment.
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2.
  • Häggström, Lennart, et al. (författare)
  • Structural transformations in lithiated Mn2Sb electrodes probed by Mossbauer spectroscopy and X-ray diffraction
  • 2006
  • Ingår i: Hyperfine Interactions. - : Springer Science and Business Media LLC. - 0304-3843 .- 1572-9540. ; 167:1-3, s. 759-765
  • Tidskriftsartikel (refereegranskat)abstract
    • The electrochemical reactions of Li with Mn2Sb and small amounts of MnSb have been investigated by Mossbauer spectroscopy and X-ray diffraction. The lithiation transforms initially the MnSb part and later the Mn2Sb part into amorphous LiMnSb. On further lithiation the LiMnSb phase transforms to rather well crystallized Li3Sb. In the X-ray diffraction pattern for the fully lithiated sample extruded nanocrystalline Mn is seen for the first time in these type of electrodes. The first delithiation of Li3Sb results in a mixture of three phases Mn2Sb, MnSb and LiMnSb. After several cycles (charges and discharges) of the electrode the Mn2Sb phase disappears completely.
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