| 1. |
- Yu, Tao, 1988, et al.
(författare)
-
Metabolic reconfiguration enables synthetic reductive metabolism in yeast
- 2022
-
Ingår i: Nature Metabolism. - : Springer Science and Business Media LLC. - 2522-5812. ; 4:11, s. 1551-1559
-
Tidskriftsartikel (refereegranskat)abstract
- Cell proliferation requires the integration of catabolic processes to provide energy, redox power and biosynthetic precursors. Here we show how the combination of rational design, metabolic rewiring and recombinant expression enables the establishment of a decarboxylation cycle in the yeast cytoplasm. This metabolic cycle can support growth by supplying energy and increased provision of NADPH or NADH in the cytosol, which can support the production of highly reduced chemicals such as glycerol, succinate and free fatty acids. With this approach, free fatty acid yield reached 40% of theoretical yield, which is the highest yield reported for Saccharomyces cerevisiae to our knowledge. This study reports the implementation of a synthetic decarboxylation cycle in the yeast cytosol, and its application in achieving high yields of valuable chemicals in cell factories. Our study also shows that, despite extensive regulation of catabolism in yeast, it is possible to rewire the energy metabolism, illustrating the power of biodesign.
|
|
| 2. |
- Han, Yilin, et al.
(författare)
-
171 Scandium-based full Heusler compounds : A comprehensive study of competition between XA and L21 atomic ordering
- 2019
-
Ingår i: Results in Physics. - : Elsevier. - 2211-3797. ; 12, s. 435-446
-
Tidskriftsartikel (refereegranskat)abstract
- The site-preference rule (SPR), which is widely used to design and study the properties of full-Heusler alloys X2YZ, is applied to determine the positions of different transition-metal elements with various numbers of valence electrons in Heusler alloys. The scandium-based full Heusler alloys should form an XA structure according to the SPR, because the transition-metal element Sc with fewer valence electrons tends to occupy the Wyckoff sites A(0, 0, 0) and B(0.25, 0.25, 0.25). As opposed to previous investigations, L21-type scandium-based full Heusler alloys, which do not follow the SPR, are also considered in this work. Theoretical computations are used to study the atomic-site preferences of 171 scandium-based full Heusler alloys, and the results indicate that most of these alloys form L21-type structures rather than XA-type structures. Two possible orderings are also studied in terms of their difference in charge density. Furthermore, the ground state, electronic structure, and magnetic characteristics of these alloys are also investigated in detail in both XA and L21 structures. The results reveal dramatic differences between XA- and L21-type alloys. This study thus presents a counterexample of the SPR rule and should provide significant guidance for the future design of full-Heusler alloys.
|
|
| 3. |
- Sun, Haonan, et al.
(författare)
-
Large energy storage density in BiFeO3-BaTiO3-AgNbO3 lead-free relaxor ceramics
- 2020
-
Ingår i: Journal of the European Ceramic Society. - : Elsevier. - 0955-2219 .- 1873-619X. ; 40:8, s. 2929-2935
-
Tidskriftsartikel (refereegranskat)abstract
- Lead-free (0.70-x)BiFeO3-0.30BaTiO3-xAgNbO3+5‰mol CuO (abbreviated as BF-BT-xAN) ceramics were fabricated using a modified thermal quenching technique. BF-BT-xAN ceramics are of a perovskite structure with morphotropic phase boundary (MPB) and show strong relaxor properties. Remarkably, the high recoverable energy storage density of 2.11 J/cm3 is obtained for BF-BT-xAN with x = 0.14. For the x = 0.14 ceramics, its energy storage efficiency is as high as 84 % at relative low field of 195 kV/cm, together with an outstanding thermal stability in a broad temperature range from 25 °C to 150 °C. In addition, this ceramic maintains superior energy storage performance even after 8 × 104 electrical cycles due to its high densification after doping Ag2O and Nb2O5. The result suggests that lead-free BF-BT-xAN ceramics may be promising candidate for dielectric energy storage application.
|
|
| 4. |
|
|
| 5. |
- Zhang, Jiangbin, et al.
(författare)
-
Efficient non-fullerene organic solar cells employing sequentially deposited donor-acceptor layers
- 2018
-
Ingår i: Journal of Materials Chemistry A. - : ROYAL SOC CHEMISTRY. - 2050-7488 .- 2050-7496. ; 6:37, s. 18225-18233
-
Tidskriftsartikel (refereegranskat)abstract
- Non-fullerene acceptors (NFAs) have recently outperformed their fullerene counterparts in binary bulk-heterojunction (BHJ) organic solar cells (OSCs). Further development of NFA OSCs may benefit other novel OSC device structures that alter or extend the standard BHJ concept. Here, we report such a new processing route that forms a BHJ-like morphology between sequentially processed polymer donor and NFA with high power conversion efficiencies in excess of 10%. Both devices show similar charge generation and recombination behaviours, supporting formation of similar BHJ active layers. We correlate the approximate to 30 meV smaller open-circuit voltage in sq-BHJ devices to more substantial non-radiative recombination by voltage loss analysis. We also determine the exciton diffusion length of benchmark polymer PBDB-T to be 10 +/- 3 nm. Our results demonstrate high-efficiency OSC devices using sequential deposition method and provide new opportunities to further improve performance of state-of-the-art OSCs.
|
|
