SwePub
Sök i SwePub databas

  Utökad sökning

Träfflista för sökning "WFRF:(Lloyd Jeremy M.) "

Sökning: WFRF:(Lloyd Jeremy M.)

  • Resultat 1-3 av 3
Sortera/gruppera träfflistan
   
NumreringReferensOmslagsbildHitta
1.
  • 2019
  • Tidskriftsartikel (refereegranskat)
  •  
2.
  • Aebersold, Ruedi, et al. (författare)
  • How many human proteoforms are there?
  • 2018
  • Ingår i: Nature Chemical Biology. - : NATURE PUBLISHING GROUP. - 1552-4450 .- 1552-4469. ; 14:3, s. 206-214
  • Tidskriftsartikel (refereegranskat)abstract
    • Despite decades of accumulated knowledge about proteins and their post-translational modifications (PTMs), numerous questions remain regarding their molecular composition and biological function. One of the most fundamental queries is the extent to which the combinations of DNA-, RNA-and PTM-level variations explode the complexity of the human proteome. Here, we outline what we know from current databases and measurement strategies including mass spectrometry-based proteomics. In doing so, we examine prevailing notions about the number of modifications displayed on human proteins and how they combine to generate the protein diversity underlying health and disease. We frame central issues regarding determination of protein-level variation and PTMs, including some paradoxes present in the field today. We use this framework to assess existing data and to ask the question, "How many distinct primary structures of proteins (proteoforms) are created from the 20,300 human genes?" We also explore prospects for improving measurements to better regularize protein-level biology and efficiently associate PTMs to function and phenotype.
  •  
3.
  • Perner, Kerstin, et al. (författare)
  • Establishment of modern circulation pattern at c. 6000 cal a BP in Disko Bugt, central West Greenland : opening of the Vaigat Strait
  • 2013
  • Ingår i: Journal of Quaternary Science. - : Wiley. - 0267-8179 .- 1099-1417. ; 28:5, s. 480-489
  • Tidskriftsartikel (refereegranskat)abstract
    • Variations in the Holocene circulation of the West Greenland Current (WGC) in the Disko Bugt region have been reconstructed from a suite of sediment cores. Palaeoceanographic proxies include magnetic susceptibility (MS) and X-ray fluorescence titanium counts, which document a major shift in circulation at c. 6000 cal a BP. Before this date, sediments in southern Disko Bugt were characterized by high terrigeneous and basaltic input, suggesting widespread influence of meltwater plumes. Our data show that the WGC re-circulated in the southern Disko Bugt area because a potential northern pathway, the narrow Vaigat Strait, was blocked by icebergs that calved from marine outlet glaciers in eastern Disko Bugt. Sediments in southern Disko Bugt deposited after c. 6000 cal a BP have significantly lower terrestrial and basaltic sediment input, which coincides with minimum Holocene ice sheet extent. The reduced meltwater and iceberg discharge to the embayment caused the Vaigat Strait to become free of blocking icebergs and terrigenous input was partly diverted to the outer shelf. Thus, the modern circulation pattern of the WGC was established in the Disko Bugt region through the opening of the Vaigat Strait c. 6000 cal a BP.
  •  
Skapa referenser, mejla, bekava och länka
  • Resultat 1-3 av 3
Typ av publikation
tidskriftsartikel (3)
Typ av innehåll
refereegranskat (3)
Författare/redaktör
Kelly, Daniel (1)
Bengtsson-Palme, Joh ... (1)
Nilsson, Henrik (1)
Kelly, Ryan (1)
Li, Ying (1)
Moore, Matthew D. (1)
visa fler...
Uhlén, Mathias (1)
Liu, Fang (1)
Zhang, Yao (1)
Jin, Yi (1)
Raza, Ali (1)
Rafiq, Muhammad (1)
Zhang, Kai (1)
Khatlani, T (1)
Kahan, Thomas (1)
Sörelius, Karl, 1981 ... (1)
Batra, Jyotsna (1)
Roobol, Monique J (1)
Backman, Lars (1)
Van Eyk, Jennifer E. (1)
Rodriguez, Henry (1)
Lundberg, Emma (1)
Snyder, Michael P. (1)
Aebersold, Ruedi (1)
Baker, Mark S. (1)
Yan, Hong (1)
Agar, Jeffrey N. (1)
Amster, I. Jonathan (1)
Bertozzi, Carolyn R. (1)
Boja, Emily S. (1)
Costello, Catherine ... (1)
Cravatt, Benjamin F. (1)
Fenselau, Catherine (1)
Garcia, Benjamin A. (1)
Ge, Ying (1)
Gunawardena, Jeremy (1)
Hendrickson, Ronald ... (1)
Hergenrother, Paul J ... (1)
Huber, Christian G. (1)
Ivanov, Alexander R. (1)
Jensen, Ole N. (1)
Jewett, Michael C. (1)
Kelleher, Neil L. (1)
Kiessling, Laura L. (1)
Krogan, Nevan J. (1)
Larsen, Martin R. (1)
Loo, Joseph A. (1)
Loo, Rachel R. Ogorz ... (1)
MacCoss, Michael J. (1)
Mallick, Parag (1)
visa färre...
Lärosäte
Uppsala universitet (2)
Göteborgs universitet (1)
Kungliga Tekniska Högskolan (1)
Högskolan i Halmstad (1)
Stockholms universitet (1)
Lunds universitet (1)
visa fler...
Chalmers tekniska högskola (1)
Karolinska Institutet (1)
visa färre...
Språk
Engelska (3)
Forskningsämne (UKÄ/SCB)
Naturvetenskap (2)
Medicin och hälsovetenskap (1)

År

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy