| 1. |
- Aebersold, Ruedi, et al.
(författare)
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How many human proteoforms are there?
- 2018
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Ingår i: Nature Chemical Biology. - : NATURE PUBLISHING GROUP. - 1552-4450 .- 1552-4469. ; 14:3, s. 206-214
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Tidskriftsartikel (refereegranskat)abstract
- Despite decades of accumulated knowledge about proteins and their post-translational modifications (PTMs), numerous questions remain regarding their molecular composition and biological function. One of the most fundamental queries is the extent to which the combinations of DNA-, RNA-and PTM-level variations explode the complexity of the human proteome. Here, we outline what we know from current databases and measurement strategies including mass spectrometry-based proteomics. In doing so, we examine prevailing notions about the number of modifications displayed on human proteins and how they combine to generate the protein diversity underlying health and disease. We frame central issues regarding determination of protein-level variation and PTMs, including some paradoxes present in the field today. We use this framework to assess existing data and to ask the question, "How many distinct primary structures of proteins (proteoforms) are created from the 20,300 human genes?" We also explore prospects for improving measurements to better regularize protein-level biology and efficiently associate PTMs to function and phenotype.
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| 2. |
- Grossmann, Igor, et al.
(författare)
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Insights into the accuracy of social scientists' forecasts of societal change
- 2023
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Ingår i: Nature Human Behaviour. - : Springer Nature. - 2397-3374. ; 7, s. 484-501
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Tidskriftsartikel (refereegranskat)abstract
- How well can social scientists predict societal change, and what processes underlie their predictions? To answer these questions, we ran two forecasting tournaments testing the accuracy of predictions of societal change in domains commonly studied in the social sciences: ideological preferences, political polarization, life satisfaction, sentiment on social media, and gender-career and racial bias. After we provided them with historical trend data on the relevant domain, social scientists submitted pre-registered monthly forecasts for a year (Tournament 1; N = 86 teams and 359 forecasts), with an opportunity to update forecasts on the basis of new data six months later (Tournament 2; N = 120 teams and 546 forecasts). Benchmarking forecasting accuracy revealed that social scientists' forecasts were on average no more accurate than those of simple statistical models (historical means, random walks or linear regressions) or the aggregate forecasts of a sample from the general public (N = 802). However, scientists were more accurate if they had scientific expertise in a prediction domain, were interdisciplinary, used simpler models and based predictions on prior data. How accurate are social scientists in predicting societal change, and what processes underlie their predictions? Grossmann et al. report the findings of two forecasting tournaments. Social scientists' forecasts were on average no more accurate than those of simple statistical models.
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| 3. |
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2012 2nd Baltic Congress on Future Internet Communications
- 2012
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Proceedings (redaktörskap) (refereegranskat)abstract
- The following topics are dealt with: smart applications; next generation WLAN; broadband infrastructure; network performance; network security; user-centric solutions; wireless systems; Internet of things; smart spaces; analog integrated circuits; traffic analysis; SoC; routing; and protocols. © 2012 IEEE
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| 4. |
- Abelev, Betty, et al.
(författare)
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Long-range angular correlations on the near and away side in p-Pb collisions at root S-NN=5.02 TeV
- 2013
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Ingår i: Physics Letters. Section B: Nuclear, Elementary Particle and High-Energy Physics. - : Elsevier BV. - 0370-2693. ; 719:1-3, s. 29-41
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Tidskriftsartikel (refereegranskat)abstract
- Angular correlations between charged trigger and associated particles are measured by the ALICE detector in p-Pb collisions at a nucleon-nucleon centre-of-mass energy of 5.02 TeV for transverse momentum ranges within 0.5 < P-T,P-assoc < P-T,P-trig < 4 GeV/c. The correlations are measured over two units of pseudorapidity and full azimuthal angle in different intervals of event multiplicity, and expressed as associated yield per trigger particle. Two long-range ridge-like structures, one on the near side and one on the away side, are observed when the per-trigger yield obtained in low-multiplicity events is subtracted from the one in high-multiplicity events. The excess on the near-side is qualitatively similar to that recently reported by the CMS Collaboration, while the excess on the away-side is reported for the first time. The two-ridge structure projected onto azimuthal angle is quantified with the second and third Fourier coefficients as well as by near-side and away-side yields and widths. The yields on the near side and on the away side are equal within the uncertainties for all studied event multiplicity and p(T) bins, and the widths show no significant evolution with event multiplicity or p(T). These findings suggest that the near-side ridge is accompanied by an essentially identical away-side ridge. (c) 2013 CERN. Published by Elsevier B.V. All rights reserved.
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| 5. |
- Abelev, Betty, et al.
(författare)
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Measurement of prompt J/psi and beauty hadron production cross sections at mid-rapidity in pp collisions at root s=7 TeV
- 2012
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Ingår i: Journal of High Energy Physics. - 1029-8479. ; :11
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Tidskriftsartikel (refereegranskat)abstract
- The ALICE experiment at the LHC has studied J/psi production at mid-rapidity in pp collisions at root s = 7 TeV through its electron pair decay on a data sample corresponding to an integrated luminosity L-int = 5.6 nb(-1). The fraction of J/psi from the decay of long-lived beauty hadrons was determined for J/psi candidates with transverse momentum p(t) > 1,3 GeV/c and rapidity vertical bar y vertical bar < 0.9. The cross section for prompt J/psi mesons, i.e. directly produced J/psi and prompt decays of heavier charmonium states such as the psi(2S) and chi(c) resonances, is sigma(prompt J/psi) (p(t) > 1.3 GeV/c, vertical bar y vertical bar < 0.9) = 8.3 +/- 0.8(stat.) +/- 1.1 (syst.)(-1.4)(+1.5) (syst. pol.) mu b. The cross section for the production of b-hadrons decaying to J/psi with p(t) > 1.3 GeV/c and vertical bar y vertical bar < 0.9 is a sigma(J/psi <- hB) (p(t) > 1.3 GeV/c, vertical bar y vertical bar < 0.9) = 1.46 +/- 0.38 (stat.)(-0.32)(+0.26) (syst.) mu b. The results are compared to QCD model predictions. The shape of the p(t) and y distributions of b-quarks predicted by perturbative QCD model calculations are used to extrapolate the measured cross section to derive the b (b) over bar pair total cross section and d sigma/dy at mid-rapidity.
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| 6. |
- Abelev, Betty, et al.
(författare)
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Underlying Event measurements in pp collisions at root s=0.9 and 7 TeV with the ALICE experiment at the LHC
- 2012
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Ingår i: Journal of High Energy Physics. - 1029-8479. ; :7
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Tidskriftsartikel (refereegranskat)abstract
- We present measurements of Underlying Event observables in pp collisions at root s = 0 : 9 and 7 TeV. The analysis is performed as a function of the highest charged-particle transverse momentum p(T),L-T in the event. Different regions are defined with respect to the azimuthal direction of the leading (highest transverse momentum) track: Toward, Transverse and Away. The Toward and Away regions collect the fragmentation products of the hardest partonic interaction. The Transverse region is expected to be most sensitive to the Underlying Event activity. The study is performed with charged particles above three different p(T) thresholds: 0.15, 0.5 and 1.0 GeV/c. In the Transverse region we observe an increase in the multiplicity of a factor 2-3 between the lower and higher collision energies, depending on the track p(T) threshold considered. Data are compared to PYTHIA 6.4, PYTHIA 8.1 and PHOJET. On average, all models considered underestimate the multiplicity and summed p(T) in the Transverse region by about 10-30%.
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| 7. |
- Ahmad, Ashfaq, et al.
(författare)
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Flexible and Compact Spiral-Shaped Frequency Reconfigurable Antenna for Wireless Applications
- 2020
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Ingår i: IETE Journal of Research. - : TAYLOR & FRANCIS LTD. - 0377-2063 .- 0974-780X. ; 66:1, s. 22-29
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Tidskriftsartikel (refereegranskat)abstract
- A flexible, spiral-shaped frequency reconfigurable antenna with a compact size (20 x 24 mm(2)) is presented. The proposed antenna has a low-profile planar structure and is able to operate at five different frequency bands, i.e., 4.19-4.48, 5.98-6.4, 3.42-4.0, 5.4-5.68, and 6.8-7.0 GHz. The multiband operation enables the antenna to cover aeronautical radio navigation, fixed satellite communication, WLAN, and WiMAX standards. A radiating element is backed by Rogers (R) 5880 substrate with a thickness of 0.508 mm and dielectric constant of 2.2. The spiral shape is achieved by introducing different strips. Frequency reconfiguration is achieved by the incorporation of a lumped element in a strip, so that the antenna can switch between different resonances. To validate the performance of the antenna, the prototype of the design was fabricated and tested. Good acquiescent is seen between simulated and measured results. The proposed antenna operates efficiently with appreciable return loss, directivity, bandwidth, and peak gain.
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| 8. |
- Aslam, Bilal, et al.
(författare)
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A compact implantable RFID tag antenna dedicated to wireless health care
- 2017
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Ingår i: International Journal of RF and Microwave Computer-Aided Engineering. - : John Wiley & Sons. - 1096-4290 .- 1099-047X. ; 27:5
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Tidskriftsartikel (refereegranskat)abstract
- Implantable tag antennas are an integral component of contemporary pervasive patient monitoring setups envisioned to reduce the medical errors and improve the quality of health care facilities. These tags, embedded into the human body, transmit critical patient information to the external equipment via a wireless communication link. This research article presents an implantable compact folded dipole antenna of size 10 mm 3 15 mm 3 2 mm, designed to operate in the industrial-scientificmedical band (2.4-2.48GHz). A three-layered phantom representing the human arm is used to evaluate the subcutaneous antenna performance. The tag antenna embedded in the middle of the fat layer offers a maximum gain of 216.3 dBi. The tag antenna performance as a function of implant position and phantom dimensions is analyzed. Link budget calculations show that with the achieved antenna gain the link power exceeds the required power by 38.37 dBm, and hence wireless communication is viable.
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| 9. |
- Aslam, Bilal, et al.
(författare)
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A high capacity tunable retransmission type frequency coded chipless radio frequency identification system
- 2019
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Ingår i: International Journal of RF and Microwave Computer-Aided Engineering. - : WILEY. - 1096-4290 .- 1099-047X. ; 29:9
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Tidskriftsartikel (refereegranskat)abstract
- This article presents a 12-bit frequency coded chipless RFID system in the frequency range of 3 to 6 GHz. The system consists of a fully printable chipless tag and a pair of high-gain reader antennas. The tag also incorporates its own antennas to improve the read range. Information is encoded into frequency spectrum using a multi-resonant circuit. The circuit consists of multiple microstrip U and L-shaped open stub resonators patterned in a unique configuration. The proposed configuration aids in capturing more data in a reduced space as well as tunable frequency operation. Tag and reader antennas utilize techniques such as stepped impedance feeding line, defective partial ground plane, and stair-step patch structure to achieve wide-band impedance bandwidth in miniature size. The results of the wireless measurements in the non-anechoic environment show that the proposed system has a reading range of more than 20 cm. The presented system possesses great potential for low-cost short-range inventory tracking.
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| 10. |
- Aslam, Bilal, et al.
(författare)
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A low profile miniature RFID tag antenna dedicated to IoT applications
- 2019
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Ingår i: Electromagnetics. - : Taylor & Francis. - 0272-6343 .- 1532-527X. ; 39:6, s. 393-406
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Tidskriftsartikel (refereegranskat)abstract
- RFID tag antennas with stable performance on the diverse electromagnetic mounting platforms are an integral part of the ubiquitous RFID systems. This research article presents a novel tag antenna design that facilitates the said objective. The proposed antenna consists of a modified H-shaped slot structure that ensures considerable robustness from the application environment through confining the surface current density within the antenna structure. The antenna offers a tunable bandwidth of 40 MHz within the microwave band of (2.4-2.5) GHz. The proposed tag antenna exhibits excellent response on metallic platforms of different sizes and thicknesses with an effective gain of almost four times of that in free space. Furthermore, the designed tag antenna performs adequately well on low-medium permittivity dielectrics (glass, paper, and plastic) and RF absorbers (water). The free space and on-metal performance of the proposed tag antenna are verified by testing a prototype realized on the FR4 substrate.
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