| 1. |
|
|
| 2. |
- Ferrando, Carlos, et al.
(författare)
-
Effects of oxygen on post-surgical infections during an individualised perioperative open-lung ventilatory strategy : a randomised controlled trial
- 2020
-
Ingår i: British Journal of Anaesthesia. - : ELSEVIER SCI LTD. - 0007-0912 .- 1471-6771. ; 124:1, s. 110-120
-
Tidskriftsartikel (refereegranskat)abstract
- Background: We aimed to examine whether using a high fraction of inspired oxygen (FIO2) in the context of an individualised intra- and postoperative open-lung ventilation approach could decrease surgical site infection (SSI) in patients scheduled for abdominal surgery. Methods: We performed a multicentre, randomised controlled clinical trial in a network of 21 university hospitals from June 6, 2017 to July 19, 2018. Patients undergoing abdominal surgery were randomly assigned to receive a high (0.80) or conventional (0.3) FIO2 during the intraoperative period and during the first 3 postoperative hours. All patients were mechanically ventilated with an open-lung strategy, which included recruitment manoeuvres and individualised positive end-expiratory pressure for the best respiratory-system compliance, and individualised continuous postoperative airway pressure for adequate peripheral oxyhaemoglobin saturation. The primary outcome was the prevalence of SSI within the first 7 postoperative days. The secondary outcomes were composites of systemic complications, length of intensive care and hospital stay, and 6-month mortality. Results: We enrolled 740 subjects: 371 in the high FIO2 group and 369 in the low FIO2 group. Data from 717 subjects were available for final analysis. The rate of SSI during the first postoperative week did not differ between high (8.9%) and low (9.4%) FIO2 groups (relative risk [RR]: 0.94; 95% confidence interval [CI]: 0.59-1.50; P=0.90]). Secondary outcomes, such as atelectasis (7.7% vs 9.8%; RR: 0.77; 95% CI: 0.48-1.25; P=0.38) and myocardial ischaemia (0.6% [n=2] vs 0% [n=0]; P=0.47) did not differ between groups. Conclusions: An oxygenation strategy using high FIO2 compared with conventional FIO2 did not reduce postoperative SSIs in abdominal surgery. No differences in secondary outcomes or adverse events were found.
|
|
| 3. |
- Auffarth, Benjamin, et al.
(författare)
-
Comparison of Redundancy and Relevance Measures for Feature Selection in Tissue Classification of CT images
- 2010
-
Ingår i: Advances in Data Mining. - Heidelberg : Springer Berlin/Heidelberg. ; , s. 248-262
-
Bokkapitel (refereegranskat)abstract
- In this paper we report on a study on feature selection within the minimum-redundancy maximum-relevance framework. Features are ranked by their correlations to the target vector. These relevance scores are then integrated with correlations between features in order to ob- tain a set of relevant and least-redundant features. Applied measures of correlation or distributional similarity for redundancy and relevance include Kolmogorov-Smirnov (KS) test, Spearman correlations, Jensen-Shannon divergence, and the sign-test. We introduce a metric called “value difference metric“ (VDM) and present a simple measure, which we call “fit criterion“ (FC). We draw conclusions about the usefulness of different measures. While KS-test and sign-test provided useful information, Spearman correlations are not fit for comparison of data of different measurement intervals. VDM was very good in our experiments as both redundancy and relevance measure. Jensen-Shannon and the sign-test are good redundancy measure alternatives and FC is a good relevance measure alternative.
|
|
| 4. |
- Auffarth, Benjamin, et al.
(författare)
-
Hopfield Networks in Relevance and Redundancy Feature Selection Applied to Classification of Biomedical High-Resolution Micro-CT Images
- 2008
-
Ingår i: Advances in Data Mining. - Heidelberg : Springer. ; , s. 16-31
-
Bokkapitel (refereegranskat)abstract
- We study filter-based feature selection methods for classification of biomedical images. For feature selection, we use two filters - a relevance filter which measures usefulness of individual features for target prediction, and a redundancy filter, which measures similarity between features. As selection method that combines relevance and redundancy we try out a Hopfield network. We experimentally compare selection methods, running unitary redundancy and relevance filters, against a greedy algorithm with redundancy thresholds [9], the min-redundancy max-relevance integration [8,23,36], and our Hopfield network selection. We conclude that on the whole, Hopfield selection was one of the most successful methods, outperforming min-redundancy max-relevance when more features are selected.
|
|
| 5. |
- Auffarth, Benjamin, et al.
(författare)
-
System for Automated Assistance in Correction of Programming Exercises (SAC)
- 2008
-
Ingår i: Proceedings of CIDUI 2008. - Lleida (Spain). ; , s. 104-113
-
Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- In university programming classes often hundreds of students participate having to solveeach hundreds of programming assignments a situation which puts instructors to the difficult task of validating hundreds of programming assignments. We present a framework thatcan help instructors and students in organization and validation of program code. Our “System for Automated Assistance in Correction of Programming Exercises“ (short: SAC) is aweb-platform for test-driven development and automated validation. The web-platform isbased on Java Server Pages technology with tomcat as servlet container, and allows teachersto specify and define program exercises and students to upload their solutions. Students can get immediate feedback on the validity of their code and both instructors and students cansee statistics about each programming assignment. We explain our platform and proposehow the automatic validation can be extended.
|
|
| 6. |
- Dignum, Virginia, Professor, et al.
(författare)
-
Ethics by Design : necessity or curse?
- 2018
-
Ingår i: Proceedings of the 2018 AAAI/ACM Conference on AI, Ethics, and Society. - New York : ACM Publications. - 9781450360128 ; , s. 60-66
-
Konferensbidrag (refereegranskat)
|
|
