| 1. |
- Bernal, Ximena E., et al.
(författare)
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Empowering Latina scientists
- 2019
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Ingår i: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 363:6429, s. 825-826
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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| 2. |
- Bousquet, Jean, et al.
(författare)
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ARIA digital anamorphosis : Digital transformation of health and care in airway diseases from research to practice
- 2021
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Ingår i: Allergy. European Journal of Allergy and Clinical Immunology. - : John Wiley & Sons. - 0105-4538 .- 1398-9995. ; 76:1, s. 168-190
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Forskningsöversikt (refereegranskat)abstract
- Digital anamorphosis is used to define a distorted image of health and care that may be viewed correctly using digital tools and strategies. MASK digital anamorphosis represents the process used by MASK to develop the digital transformation of health and care in rhinitis. It strengthens the ARIA change management strategy in the prevention and management of airway disease. The MASK strategy is based on validated digital tools. Using the MASK digital tool and the CARAT online enhanced clinical framework, solutions for practical steps of digital enhancement of care are proposed.
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| 3. |
- Anderson, Beverley H., et al.
(författare)
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Mutations in CTC1, encoding conserved telomere maintenance component 1, cause Coats plus
- 2012
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Ingår i: Nature Genetics. - : Springer Science and Business Media LLC. - 1061-4036 .- 1546-1718. ; 44:3, s. 338-342
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Tidskriftsartikel (refereegranskat)abstract
- Coats plus is a highly pleiotropic disorder particularly affecting the eye, brain, bone and gastrointestinal tract. Here, we show that Coats plus results from mutations in CTC1, encoding conserved telomere maintenance component 1, a member of the mammalian homolog of the yeast heterotrimeric CST telomeric capping complex. Consistent with the observation of shortened telomeres in an Arabidopsis CTC1 mutant and the phenotypic overlap of Coats plus with the telomeric maintenance disorders comprising dyskeratosis congenita, we observed shortened telomeres in three individuals with Coats plus and an increase in spontaneous gamma H2AX-positive cells in cell lines derived from two affected individuals. CTC1 is also a subunit of the alpha-accessory factor (AAF) complex, stimulating the activity of DNA polymerase-alpha primase, the only enzyme known to initiate DNA replication in eukaryotic cells. Thus, CTC1 may have a function in DNA metabolism that is necessary for but not specific to telomeric integrity.
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| 4. |
- Lourenço, José A. S., et al.
(författare)
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Non-Hermitian dynamics and PT-symmetry breaking in interacting mesoscopic Rydberg platforms
- 2022
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Ingår i: Physical Review A: covering atomic, molecular, and optical physics and quantum information. - 2469-9926 .- 2469-9934. ; 106:2
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Tidskriftsartikel (refereegranskat)abstract
- We simulate the dissipative dynamics of a mesoscopic system of long-range interacting particles which can be mapped into non-Hermitian spin models with a PT symmetry. We find rich PT phase diagrams with PT-symmetric and PT-broken phases. The dynamical regimes can be further enriched by modulating tunable parameters of the system. We outline how the PT symmetries of such systems may be probed by studying their dynamics. We note that systems of Rydberg atoms and systems of Rydberg ions with strong dipolar interactions are particularly well suited for such studies. We present a viable proposal for implementing non-Hermitian physics with PT symmetry in Rydberg systems. We show that for realistic parameters, long-range interactions allow the emergence of new PT-symmetric regions, generating new PT phase transitions. In addition, such PT-symmetry phase transitions are found by changing the configurations of the Rydberg atoms. We propose a post selection scheme on an ensemble of Rydberg ions described by an effective three-level system. Detecting the population dynamics, the system shows an oscillatory behavior in the PT-unbroken phase and a stationary population for long times in the PT-broken phase.
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