| 1. |
- Armbrecht, John, et al.
(författare)
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Swedish Sports Clubs and Events during the Covid-19 Pandemic: Impacts and Responses
- 2021
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Ingår i: Crisis Management and Recovery for Events: Impacts and Strategies. - Oxford : Goodfellow Publishers. - 9781911635901 ; , s. 193-212
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Bokkapitel (refereegranskat)abstract
- Sweden has 10 million inhabitants of which more than 30% are members of at least one sports club. Typically, sports clubs are organized under the Swedish Sports Confederation (Riksidrottsförbundet). On a national level, approximately 19,000 sports clubs exist, distributed over 72 specialist sports federations. Each club usually stages one or several sport events every year. For example, specialist sports federations organize all championships at national and international levels. From a sports club perspective, these events constitute important sources of income. From a societal perspective, clubs and events create considerable economic impacts, foster public health, and facilitate integration contributing with substantial social values (Brown et al., 2015; Pettersson & Wallstam, 2017; Wallstam, Ioannides, & Pettersson, 2020). During the Covid-19 pandemic, most governments restricted individuals’ possibilities for gatherings and movements. On March 12th the Swedish government responded to the pandemic by limiting the number of participants to events to no more than 500 people. Starting March 29th gatherings were limited to 50 people. During the end of year 2020 and the second virus wave, further actions were taken. The government limited the number of visitors and participants to eight people. These restrictions had considerable negative effects on many sport-related activities, events, and thus clubs.
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| 4. |
- Borgmästars, Emmy, et al.
(författare)
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Circulating tissue polypeptide-specific antigen in pre-diagnostic pancreatic cancer samples
- 2021
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Ingår i: Cancers. - : MDPI. - 2072-6694. ; 13:21
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Tidskriftsartikel (refereegranskat)abstract
- Early detection of pancreatic ductal adenocarcinoma (PDAC) is challenging, and late diagnosis partly explains the low 5-year survival. Novel and sensitive biomarkers are needed to enable early PDAC detection and improve patient outcomes. Tissue polypeptide specific antigen (TPS) has been studied as a biomarker in PDAC diagnostics, and it has previously been shown to reflect clinical status better than the ‘golden standard’ biomarker carbohydrate antigen 19-9 (CA 19-9) that is most widely used in the clinical setting. In this cross-sectional case-control study using pre-diagnostic plasma samples, we aim to evaluate the potential of TPS as a biomarker for early PDAC detection. Furthermore, in a subset of individuals with multiple samples available at different time points before diagnosis, a longitudinal analysis was used. We assessed plasma TPS levels using enzyme-linked immunosorbent assay (ELISA) in 267 pre-diagnostic PDAC plasma samples taken up to 18.8 years before clinical PDAC diagnosis and in 320 matched healthy controls. TPS levels were also assessed in 25 samples at PDAC diagnosis. Circulating TPS levels were low both in pre-diagnostic samples of future PDAC patients and in healthy controls, whereas TPS levels at PDAC diagnosis were significantly increased (odds ratio 1.03; 95% confidence interval: 1.01–1.05) in a logistic regression model adjusted for age. In conclusion, TPS levels increase late in PDAC progression and hold no potential as a biomarker for early detection.
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| 5. |
- Edqvist, Erik, 1975-
(författare)
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Applications of active materials
- 2009
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Energy efficiency is a vital key component when designing and miniaturizing self sustained microsystems. The smaller the system, the smaller is the possibility to store enough stored energy for a long and continuous operational time. To move such a system in an energy efficient way, a piezoelectrical locomotion module consisting of four resonating cantilevers has been designed, manufactured and evaluated in this work. The combination of a suitable substrate, a multilayered piezoelectric material to reduce the voltage, and a resonating drive mechanism resulted in a low power demand. A manufacturing process for multilayer cantilever actuators made of P(VDF-TrFE) with aluminum electrodes on a substrate of flexible printed circuit board (FPC), has been developed. An important step in this process was the development of an etch recipe for dry etching the multilayer actuators in an inductive plasma equipment. Formulas for the quasi static tip deflection and resonance frequency of a multilayered cantilever, have been derived. Through theses, it was found that the multilayered structures should be deposited on the polymer side of the FPC in order to maximize the tip deflection. Both a large and a miniaturized locomotion module were manufactured and connected by wires to verify that the three legged motion principal worked to move the structures forward and backward, and turn it right and left. By touching and adding load, to a fourth miniaturized cantilever, its ability to act as a contact sensor and carry object was verified. The presented locomotion module is part of a multifunctional microsystem, intended to be energy efficient and powered by a solar panel with a total volume of less than 25 mm3 and weight 65 mg. The whole system, consisting of a solar cell, an infra red communication module, an integrated circuit for control, three capacitors for power regulating, the locomotion module and an FPC connecting the different modules, was surface mounted using a state of the art industrial facility. Two fully assembled systems could be programmed both through a test connector and through optical sensors in the multifunctional solar cell. One of these was folded together to the final configuration of a robot. However, the entire system could not be tested under full autonomous operating conditions. On the other hand, using wires, the locomotion module could be operated and used to move the entire system from a peak-to-peak voltage of 3.0 V.
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| 6. |
- Ekholm, David, 1980-, et al.
(författare)
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Rättighetsarbete med egen erfarenhet som grund
- 2023
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Ingår i: De sociala rättigheternas politik. - Malmö : Gleerups Utbildning AB. - 9789151109855 ; , s. 203-220
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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| 7. |
- Gaddefors, Johan, et al.
(författare)
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Rural entrepreneurship research : promoting reflexivity or functional stupidity?
- 2013
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Ingår i: Conference abstracts. - : University of West Scotland.
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- This paper departs from an ongoing interactive research project on entrepreneurial enclaves in southern Sweden aimed at promoting regional development through interaction between local stakeholders, academic researchers and undergraduate university students in three different municipalities. The logic of the project is that university students and academic researchers launch projects in the three municipalities. The projects are planned and performed with support from the local community. By initiating projects in the three municipalities, the research idea is that processes will start that can lead to new initiatives. Through initiating action and interaction the aim of the project is, in an experimental way, to see how entrepreneurship is mobilized. The question is how activities develop in the municipalities as a result of the research project, and how conflicts and resistance partake in this process.After having worked with the research project for half a year two issues surprised us; the conformity of the ideas in our three enclaves and the close relatedness, when it comes to practical solutions, between practice and academia. The research project seemed to have resulted in standardized, expected and widespread, common solutions to the kinds of problems and opportunities that are ascribed to the rural areas. As the solutions produced within the project are collaboratively discussed and decided upon by academic staff and local stakeholders, the fault of this lack of imagination seem to be a problem for all of us. Preconceptions about what is important in rural entrepreneurship guide us as researchers when we try to understand the field. Preconceptions were also a point of departure in the enclaves we studied, resulting in a few common solutions for how to cope with downturn and produce regional development. In this paper we are using the concept of functional stupidity (Alvesson & Spicer, 2012) to reflect upon the benefits as well as the drawbacks of the tendency, in the academy as well as in society at large, to produce a stereotypical menu of problems and suggested solutions when it comes to rural development. We also discuss the possibility to break this norm by promoting a kind of reflexivity that has the potential to produce surprising and norm-breaking ideas in the area of rural development.
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| 8. |
- Gaddefors, Johan, et al.
(författare)
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Staging rural entrepreneurship
- 2014
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Ingår i: Presented at the 12th Rural Entrepreneurship Conference, Harper Adams University, Shropshire, UK, June 18-19, 2014. ; , s. 1-16
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)
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| 10. |
- Henningsson, Susanne, 1977, et al.
(författare)
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Genetic Variation in Brain-Derived Neurotrophic Factor Is Associated with Serotonin Transporter but Not Serotonin-1A Receptor Availability in Men
- 2009
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Ingår i: Biological Psychiatry. - : Elsevier BV. - 0006-3223 .- 1873-2402. ; 66:5, s. 477-485
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Tidskriftsartikel (refereegranskat)abstract
- Background: The serotonergic system, including the serotonin transporter (5-HTT), which is the target of many antidepressants, seems to be influenced by brain-derived neurotrophic factor (BDNF). Methods: Positron emission tomography (PET) was used to address, in 25 and 53 healthy volunteers, respectively, the possible association between six polymorphisms in the gene encoding BDNF and the availability of two proteins expressed by serotonergic neurons: the 5-HTT, measured with the radioligand [C-11]MADAM, and the serotonin-1A (5-HT1A) receptor, measured with [C-11]WAY-100635. Results: Several single nucleotide polymorphisms were associated with [C-11]MADAM binding potential (BP) in most brain regions, male carriers of the valine/valine genotype of the Val66Met polymorphism displaying higher availability. Effect sizes ranged from a 50% to a threefold increase. In contrast, there was no association for [C-11]WAY-100635 BP. The observation that BDNF polymorphisms were associated with 5-HTT availability could be partly replicated in an independent population comprising nine male suicide attempters and nine matched control subjects, in which transporter availability had been measured with single photon emission computed tomography with I-123-beta-CIT as ligand. Conclusions: Our results suggest that genetic variation in BDNF influences 5-HTT but not 5-HT1A receptor density in the human brain.
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