| 1. |
- Ameur, Adam, et al.
(författare)
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SweGen : a whole-genome data resource of genetic variability in a cross-section of the Swedish population
- 2017
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Ingår i: European Journal of Human Genetics. - : NATURE PUBLISHING GROUP. - 1018-4813 .- 1476-5438. ; 25:11, s. 1253-1260
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Tidskriftsartikel (refereegranskat)abstract
- Here we describe the SweGen data set, a comprehensive map of genetic variation in the Swedish population. These data represent a basic resource for clinical genetics laboratories as well as for sequencing-based association studies by providing information on genetic variant frequencies in a cohort that is well matched to national patient cohorts. To select samples for this study, we first examined the genetic structure of the Swedish population using high-density SNP-array data from a nation-wide cohort of over 10 000 Swedish-born individuals included in the Swedish Twin Registry. A total of 1000 individuals, reflecting a cross-section of the population and capturing the main genetic structure, were selected for whole-genome sequencing. Analysis pipelines were developed for automated alignment, variant calling and quality control of the sequencing data. This resulted in a genome-wide collection of aggregated variant frequencies in the Swedish population that we have made available to the scientific community through the website https://swefreq.nbis.se. A total of 29.2 million single-nucleotide variants and 3.8 million indels were detected in the 1000 samples, with 9.9 million of these variants not present in current databases. Each sample contributed with an average of 7199 individual-specific variants. In addition, an average of 8645 larger structural variants (SVs) were detected per individual, and we demonstrate that the population frequencies of these SVs can be used for efficient filtering analyses. Finally, our results show that the genetic diversity within Sweden is substantial compared with the diversity among continental European populations, underscoring the relevance of establishing a local reference data set.
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| 2. |
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| 3. |
- Abrahamsson, Johan, et al.
(författare)
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On the Efficiency of a Two-Power-Level Flywheel-Based All-Electric Driveline
- 2012
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Ingår i: Energies. - : MDPI AG. - 1996-1073. ; 5:8, s. 2794-2817
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Tidskriftsartikel (refereegranskat)abstract
- This paper presents experimental results on an innovative electric driveline employing a kinetic energy storage device as energy buffer. A conceptual division of losses in the system was created, separating the complete system into three parts according to their function. This conceptualization of the system yielded a meaningful definition of the concept of efficiency. Additionally, a thorough theoretical framework for the prediction of losses associated with energy storage and transfer in the system was developed. A large number of spin-down tests at varying pressure levels were performed. A separation of the measured data into the different physical processes responsible for power loss was achieved from the corresponding dependence on rotational velocity. This comparison yielded an estimate of the perpendicular resistivity of the stranded copper conductor of 2.5 x 10(-8) +/- 3.5 x 10(-9). Further, power and energy were measured system-wide during operation, and an analysis of the losses was performed. The analytical solution was able to reproduce the measured distribution of losses in the system to an accuracy of 4.7% (95% CI). It was found that the losses attributed to the function of kinetic energy storage in the system amounted to between 45% and 65%, depending on usage.
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| 4. |
- Abrahamsson, Johan, et al.
(författare)
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Prototype of electric driveline with magnetically levitated double wound motor
- 2010
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Ingår i: Electrical Machines (ICEM), 2010 XIX International Conference on.
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Konferensbidrag (refereegranskat)abstract
- This paper presents the ongoing work of constructing a complete driveline for an electric road vehicle, using a flywheel as auxiliary energy storage. The flywheel energy storage system (FESS) is connected in series between the main energy storage (batteries) and the wheel motor of the vehicle, allowing the batteries to deliver power to the system in an optimized way, while at the same time making efficient use of regenerative braking. A double wound permanent magnet electric machine is used to electrically separate the two sides. In order to minimize losses, the machine has a double rotor configuration and is suspended with magnetic bearings. A bench test set-up is being constructed to investigate the properties of this system in detail. This set-up will achieve a level of power and energy close to that of a full scale system. This will allow measurements of complete drive cycles to be performed, improving the understanding of the constituting components and optimization of the complete system.
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| 5. |
- Askander, Mikael, et al.
(författare)
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Lady Gaga : scenerna, medierna, fansen
- 2014
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Ingår i: Coda: en andra antologi om musik och samhälle.
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Bokkapitel (refereegranskat)abstract
- This is a mapping of my upcoming project on the field of short culture phenomena. One part of that will deal with the music videos of Lady Gaga. In this book chapter I present som basic information on Lady Gaga, and suggestions on how to approach the artist and her artistic/aesthetic expressions. Scenes, stage performance, media, and the different relation to the fans is put into focus, and I mean that one must both take all these aspects into account, and deal with them as combined/integrated parts of thw whole, when trying to understand Lady Gagas world of ideas.
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| 6. |
- Boissin, Constance, et al.
(författare)
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Development and evaluation of deep learning algorithms for assessment of acute burns and the need for surgery
- 2023
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Ingår i: Scientific Reports. - : Springer Nature. - 2045-2322. ; 13:1
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Tidskriftsartikel (refereegranskat)abstract
- Assessment of burn extent and depth are critical and require very specialized diagnosis. Automated image-based algorithms could assist in performing wound detection and classification. We aimed to develop two deep-learning algorithms that respectively identify burns, and classify whether they require surgery. An additional aim assessed the performances in different Fitzpatrick skin types. Annotated burn (n = 1105) and background (n = 536) images were collected. Using a commercially available platform for deep learning algorithms, two models were trained and validated on 70% of the images and tested on the remaining 30%. Accuracy was measured for each image using the percentage of wound area correctly identified and F1 scores for the wound identifier; and area under the receiver operating characteristic (AUC) curve, sensitivity, and specificity for the wound classifier. The wound identifier algorithm detected an average of 87.2% of the wound areas accurately in the test set. For the wound classifier algorithm, the AUC was 0.885. The wound identifier algorithm was more accurate in patients with darker skin types; the wound classifier was more accurate in patients with lighter skin types. To conclude, image-based algorithms can support the assessment of acute burns with relatively good accuracy although larger and different datasets are needed.
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| 9. |
- de Santiago Ochoa, Juan, et al.
(författare)
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Design Parameters Calculation of a Novel Driveline for Electric Vehicles
- 2009
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Ingår i: World Electric Vehicle Journal. - 2032-6653. ; 3
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Tidskriftsartikel (refereegranskat)abstract
- A driveline for electric vehicles is presented. The propulsion system is operated at a higher voltage than the primary energy source. The batteries selected as the primary energy source deliver power to the vehicle through a motor-generator wounded with two electrically isolated sets of windings, named Two Voltage Level Machine (TVLM). The dynamic behaviour of a vehicle operating according to a standard drive cycle is studied. Parameters of the driveline such as power rates and size of the flywheel are obtained by optimization. A description of the performance of a TVLM is also presented through its equivalent circuit and the control of the machine. Special attention to the system losses is presented. A scale prototype has been constructed and tested under a drive cycle, demonstrating the system performance of the system.
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