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- Crispin Quiñonez, Veronica, et al.
(författare)
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On ideals generated by two generic quadratic forms in the exterior algebra
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Annan publikation (övrigt vetenskapligt/konstnärligt)abstract
- Based on the structure theory of pairs of skew-symmetric matrices, we give a conjecture for the Hilbert series of the exterior algebra modulo the ideal generated by two generic quadratic forms. We show that the conjectured series is an upper bound in the coefficient-wise sense, and we determine a majority of the coefficients. We also conjecture that the series is equal to the series of the squarefree polynomial ring modulo the ideal generated by the squares of two generic linear forms.
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- Crispin Quiñonez, Veronica, et al.
(författare)
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On ideals generated by two generic quadratic forms in the exterior algebra
- 2019
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Ingår i: Journal of Pure and Applied Algebra. - : Elsevier BV. - 0022-4049 .- 1873-1376. ; 223:12, s. 5067-5082
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Tidskriftsartikel (refereegranskat)abstract
- Based on the structure theory of pairs of skew-symmetric matrices, we give a conjecture for the Hilbert series of the exterior algebra modulo the ideal generated by two generic quadratic forms. We show that the conjectured series is an upper bound in the coefficient-wise sense, and we determine a majority of the coefficients. We also conjecture that the series is equal to the series of the squarefree polynomial ring modulo the ideal generated by the squares of two generic linear forms.
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| 6. |
- Jong, Mats, 1968-, et al.
(författare)
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A cross-sectional study on Swedish licensed nurses’ use, practice, attitudes and knowledge about Complementary and Alternative Medicine (CAM)
- 2013
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Konferensbidrag (refereegranskat)abstract
- Background: Only a few and relatively outdated population studies with respect to CAM use among the general population in Sweden exists. Those who has been made indicates that CAM usage is relatively high where 30-39% reports lifetime use and 20% use the last year, with massage, Naprapathy and Chiropracy being most common. Nurses are often involved in direct patient care and hold a unique role where issues of CAM can be communicated, but little is known about them as a group on the topic of CAM. Objective: The objective of this cross-sectional study was to describe licensed nurses’ use, practice, attitudes and knowledge about CAM. Method: In a web based survey Licensed Nurses were invited for participation through two different approaches: firstly from the member register of Vårdförbundet (the Swedish Association of Health Professionals), and secondly via a general invitation to formal and informal nursing associations, web communities and workplaces. A total number of 960 nurses responded to the survey, 83% were female and the mean age of the respondents were 46 years (±10.8). Results: Among the respondents, 83.4% reported to have used at least one CAM method within the last two years. The most prevalently used methods are within the categories of massage and Dietary supplements/probiotics/herbal remedies and Mind-Body therapies. Fifteen percent of respondents are practicing some form of CAM method; 69% of those among family and friends, 25% in a private business, and 37% (n=52) within the public health care (mostly different form of massage and mind-body practices). Of the respondents, 11.7% express that they ask patients about CAM use, the most common reason 38% (n=366) not to is lack of knowledge about CAM (and their legal position with respect to CAM). A high proportion (66%) agrees that healthcare personnel should inform clients about CAM treatments when asked about it. Conclusion: Swedish nurses do to a very high extent use different CAM methods for themselves, and also practice it to some degree. In spite of this, due to lack of knowledge, they do not regularly ask or inform patients about CAM methods. From the results of the study we can see that nurses are in need of better training and education about CAM, both in order to be able to meet the needs of the patients, but also for reasons of safety since interactions exist between dietary supplements/probiotics/herbal remedies and conventional drugs.
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- Jong, Mats, 1968-, et al.
(författare)
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A cross-sectional study on Swedish licensed nurses’ use, practice, perception and knowledge about Complementary and Alternative Medicine
- 2015
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Ingår i: Scandinavian Journal of Caring Sciences. - : Wiley. - 0283-9318 .- 1471-6712. ; 29:4, s. 642-650
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Tidskriftsartikel (refereegranskat)abstract
- Background: Only a few and relatively outdated population studies with respect to CAM use among the general population in Sweden exists. Those who has been made indicates that CAM usage is relatively high where 30-39% reports lifetime use and 20% use the last year, with massage, Naprapathy and Chiropracy being most common. Nurses are often involved in direct patient care and hold a unique role where issues of CAM can be communicated, but little is known about them as a group on the topic of CAM.Objective: The objective of this cross-sectional study was to describe licensed nurses’ use, practice, attitudes and knowledge about CAM. Method: In a web based survey Licensed Nurses were invited for participation through two different approaches: firstly from the member register of Vårdförbundet (the Swedish Association of Health Professionals), and secondly via a general invitation to formal and informal nursing associations, web communities and workplaces. A total number of 960 nurses responded to the survey, 83% were female and the mean age of the respondents were 46 years (±10.8).Results: Among the respondents, 83.4% reported to have used at least one CAM method within the last two years. The most prevalently used methods are within the categories of massage and Dietary supplements/probiotics/herbal remedies and Mind-Body therapies. Fifteen percent of respondents are practicing some form of CAM method; 69% of those among family and friends, 25% in a private business, and 37% (n=52) within the public health care (mostly different form of massage and mind-body practices). Of the respondents, 11.7% express that they ask patients about CAM use, the most common reason 38% (n=366) not to is lack of knowledge about CAM (and their legal position with respect to CAM). A high proportion (66%) agrees that healthcare personnel should inform clients about CAM treatments when asked about it.Conclusion: Swedish nurses do to a very high extent use different CAM methods for themselves, and also practice it to some degree. In spite of this, due to lack of knowledge, they do not regularly ask or inform patients about CAM methods. From the results of the study we can see that nurses are in need of better training and education about CAM, both in order to be able to meet the needs of the patients, but also for reasons of safety since interactions exist between dietary supplements/probiotics/herbal remedies and conventional drugs.
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- Nilsson, Kerstin, et al.
(författare)
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Vi är oroade över senare ålderspension
- 2017
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Ingår i: Dagens Samhälle. - 1652-6511.
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Tidskriftsartikel (populärvet., debatt m.m.)abstract
- Var fjärde person blir i dag sjuk till följd av sitt arbete. Att höja pensionsåldern för alla yrkesgrupper, utan konkreta åtgärder för att minska ohälsan, är därför problematiskt och mycket oroande. Det är, enligt forskarna, inte långsiktigt samhällsekonomiskt lönsamt att utan andra åtgärder höja pensionsåldern för alla. Vi – 54 forskare – är mycket oroade över konsekvenserna av att, som föreslagits, senarelägga ålderspensionen.Förslaget utgår i princip från arbetskraftsdeltagande i princip enbart styrs av ekonomin, medan forskningen visar att det bara är en av flera faktorer som styr hur länge och hur mycket människor väljer att arbeta.Det här sättet att lösa problemet med en åldrande befolkning och ett sviktande pensionssystem är inte samhällsekonomiskt lönsamt på lång sikt, utan riskerar bara att flytta runt folk mellan olika ersättningssystem. Pensionssystemet bygger på att vi ska arbeta en viss del av våra liv för att tjäna in vår pension. Vi bör dock inte enbart utgå ifrån ålder eller antalet år sedan en person föddes då korttidsutbildade generellt träder in på arbetsmarknaden tidigare än långtidsutbildade. De med kortare utbildningstid har alltså varit en del av arbetskraften från en yngre ålder. Människor med kortare utbildning har också oftare ett arbete som innebär påfrestningar som kan inverka negativt på hälsotillståndet och som till och med kan påskynda det biologiska åldrandet. Dessutom lever korttidsutbildade generellt sett inte lika länge som långtidsutbildade, vilket delvis även avspeglar skilda livs- och arbetsvillkor.Ta nytta av den forskning som vi har tagit fram. Ekonomin är självklart viktigt för att vi ska vilja arbeta, men den är som sagt enbart en av flera faktorer med betydelse vårt arbetsliv.Hälsotillståndet, både det fysiska och det mentala, har en avgörande betydelse för hur länge och hur mycket vi orkar arbeta. Ett fysiskt och mentalt belastande arbete är en stark riskfaktor för en nedsatt hälsa i slutet av arbetslivet. Arbetstid, arbetstakt och möjlighet till återhämtning spelar en allt större roll ju äldre vi blir. Andra aspekter är arbetsinnehåll, hur meningsfulla och stimulerande arbetsuppgifterna är, balansen mellan arbete och familjesituation och fritidsaktiviteter. Organisationskultur, ledarskapet, stöd i arbetet och kompetens har stor betydelse för om vi ska kunna och vilja arbeta till en högre ålder. Vi måste ta större hänsyn till olika förutsättningar och varierande funktionsförmåga och utifrån detta anpassa de åtgärder som gör att arbetslivet blir möjligt och hållbart för allt fler även i högre ålder.Ett hållbart och acceptabelt pensionssystem måste därför utformas utifrån personliga förutsättningar och förhållanden i arbetslivet. Ett hållbart arbetsliv för allt fler i vår åldrande befolkning fordrar att vi samtidigt beaktar faktorer som relaterar till biologisk/kroppslig ålder, mental/kognitiv ålder samt social ålder/livsloppsfas samt de attityder som är kopplade till ålder.
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- Rodriguez Camargo, Diana C., et al.
(författare)
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Surface-Catalyzed Secondary Nucleation Dominates the Generation of Toxic IAPP Aggregates
- 2021
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Ingår i: Frontiers in Molecular Biosciences. - : Frontiers Media SA. - 2296-889X. ; 8
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Tidskriftsartikel (refereegranskat)abstract
- The aggregation of the human islet amyloid polypeptide (IAPP) is associated with diabetes type II. A quantitative understanding of this connection at the molecular level requires that the aggregation mechanism of IAPP is resolved in terms of the underlying microscopic steps. Here we have systematically studied recombinant IAPP, with amidated C-terminus in oxidised form with a disulphide bond between residues 3 and 7, using thioflavin T fluorescence to monitor the formation of amyloid fibrils as a function of time and IAPP concentration. We used global kinetic analyses to connect the macroscopic measurements of aggregation to the microscopic mechanisms, and show that the generation of new aggregates is dominated by the secondary nucleation of monomers on the fibril surface. We then exposed insulinoma cells to aliquots extracted from different time points of the aggregation process, finding the highest toxicity at the midpoint of the reaction, when the secondary nucleation rate reaches its maximum. These results identify IAPP oligomers as the most cytotoxic species generated during IAPP aggregation, and suggest that compounds that target secondary nucleation of IAPP could be most effective as therapeutic candidates for diabetes type II.
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