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Sökning: WFRF:(Lundström Karin)

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  • Bivik Stadler, Caroline, 1986-, et al. (författare)
  • Proactive Construction of an Annotated Imaging Database for Artificial Intelligence Training
  • 2021
  • Ingår i: Journal of digital imaging. - : Springer-Verlag New York. - 0897-1889 .- 1618-727X. ; 34, s. 105-115
  • Tidskriftsartikel (refereegranskat)abstract
    • Artificial intelligence (AI) holds much promise for enabling highly desired imaging diagnostics improvements. One of the most limiting bottlenecks for the development of useful clinical-grade AI models is the lack of training data. One aspect is the large amount of cases needed and another is the necessity of high-quality ground truth annotation. The aim of the project was to establish and describe the construction of a database with substantial amounts of detail-annotated oncology imaging data from pathology and radiology. A specific objective was to be proactive, that is, to support undefined subsequent AI training across a wide range of tasks, such as detection, quantification, segmentation, and classification, which puts particular focus on the quality and generality of the annotations. The main outcome of this project was the database as such, with a collection of labeled image data from breast, ovary, skin, colon, skeleton, and liver. In addition, this effort also served as an exploration of best practices for further scalability of high-quality image collections, and a main contribution of the study was generic lessons learned regarding how to successfully organize efforts to construct medical imaging databases for AI training, summarized as eight guiding principles covering team, process, and execution aspects.
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  • Lundström, Johanna, et al. (författare)
  • Cost-effective age structure and geographical distribution of boreal forest reserves
  • 2011
  • Ingår i: Journal of Applied Ecology. - : Wiley. - 0021-8901 .- 1365-2664. ; 48, s. 133-142
  • Tidskriftsartikel (refereegranskat)abstract
    • P>1. Forest reserves are established to preserve biodiversity, and to maintain natural functions and processes. Today there is heightened focus on old-growth stages, with less attention given to early successional stages. The biodiversity potential of younger forests has been overlooked, and the cost-effectiveness of incorporating different age classes in reserve networks has not yet been studied.2. We performed a reserve selection analysis in boreal Sweden using the Swedish National Forest Inventory plots. Seventeen structural variables were used as biodiversity indicators, and the cost of protecting each plot as a reserve was assessed using the Heureka system. A goal programming approach was applied, which allowed inclusion of several objectives and avoided a situation in which common indicators affected the result more than rare ones. The model was limited either by budget or area.3. All biodiversity indicators were found in all age classes, with more than half having the highest values in ages >= 100 years. Several large-tree indicators and all deadwood indicators had higher values in forests 0-14 years than in forests 15-69 years.4. It was most cost-effective to protect a large proportion of young forests since they generally have a lower net present value compared to older forests, but still contain structures of importance for biodiversity. However, it was more area-effective to protect a large proportion of old forests since they have a higher biodiversity potential per area.5. The geographical distribution of reserves selected with the budget-constrained model was strongly biassed towards the north-western section of boreal Sweden, with a large proportion of young forest, whereas the area-constrained model focussed on the south-eastern section, with dominance by the oldest age class.6. Synthesis and applications. We show that young forests with large amounts of structures important to biodiversity such as dead wood and remnant trees are cheap and cost-efficient to protect. This suggests that reserve networks should incorporate sites with high habitat quality of different forest ages. Since young forests are generally neglected in conservation, our approach is of interest also to other forest biomes where biodiversity is adapted to disturbance regimes resulting in open, early successional stages.
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  • Aili, Daniel, 1977-, et al. (författare)
  • Aggregation-Induced Folding of a de novo Designed Polypeptide Immobilized on Gold Nanoparticles
  • 2006
  • Ingår i: Journal of the American Chemical Society. - : ACS Publications. - 0002-7863 .- 1520-5126. ; 128:7, s. 2194 -2195
  • Tidskriftsartikel (refereegranskat)abstract
    • This communication reports the first steps in the construction of a novel, nanoparticle-based hybrid material for biomimetic and biosensor applications. Gold nanoparticles were modified with synthetic polypeptides to enable control of the particle aggregation state in a switchable manner, and particle aggregation was, in turn, found to induce folding of the immobilized peptides.
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  • Resultat 1-10 av 96
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