| 1. |
- Burström, Per, et al.
(författare)
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CFD-modelling of selective non-catalytic reduction of NOx in grate-kiln plants
- 2009
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Ingår i: Seventh International Conference on CFD in the Minerals and Process Industries. - : CSIRO Publishing. ; , s. 1-6
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Konferensbidrag (refereegranskat)abstract
- The overall goal of this project is to find out if selective non-catalytic reduction (SNCR) technologies can be used in grate-kiln plants for NOx reduction. The technique has, to the best knowledge of the authors, never been used in this context before despite that it is commonly used in cement and waste incineration plants. A Computational Fluid Dynamic model of parts of a real grate was created and numerical simulations with a commercial code was carried out solving the flow field. A model for spray injection into the grate was then included in the model enabling a study of the overall mixing between the injected reagent droplets and the NOx polluted air. The simulations show promising results for SNCR with urea but not with ammonia.
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| 2. |
- Burström, Per, et al.
(författare)
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CFD-modelling of selective non-catalytic reduction of NOx in grate-kiln plants
- 2010
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Ingår i: Progress in Computational Fluid Dynamics, An International Journal. - 1468-4349 .- 1741-5233. ; 10:5/6, s. 284-291
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Tidskriftsartikel (refereegranskat)abstract
- The overall goal of this project is to find out if Selective Non-Catalytic Reduction (SNCR) technologies can be used in grate-kiln plants for NOx reduction. The technique has, to the best knowledge of the authors, never been used in this context before, despite that it is commonly used in cement and waste incineration plants. A model for spray injection into the grate was included in the model enabling a study of the overall mixing between the injected reagent droplets and the NOx polluted air. The simulations indicate that the SNCR-technique works with urea, but not with ammonia.
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| 3. |
- Dahlberg-Grundberg, Michael, 1983-, et al.
(författare)
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Social Media and the Transnationalization of Mass Activism : Twitter and the labour movement
- 2016
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Ingår i: First Monday. - : University of Illinois Libraries. - 1396-0466. ; 21:8
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Tidskriftsartikel (refereegranskat)abstract
- This paper explores the labour movement organization LabourStart, a digital initiative that, by various means such as e-mail campaigns and social media use, seeks to promote workers’ rights and to strengthen the labour movement on a global scale. The main aim of this study is to analyse a) how LabourStart employs Twitter for communication and organisation and b) how the Twitter-sphere that LabourStart constitutes — and is constituted by — is geographically structured. Our dataset consisted of all tweets containing the word “labourstart” and all tweets coming from or addressing any LabourStart–related account during the period 2008–2015. As theoretical points of departure, the notions of transnationalization/translocalism were used, in part together with the concept of connective action, to conceptualise the research. In terms of methodology, network analysis was the main approach employed to obtain and visualise the findings. Our results indicate that LabourStart’s Twitter use does not seem to have had any effects in terms of creating a decentralised transnational movement with translocal traits, thus suggesting that LabourStart has failed to fully make use of the connective features of Twitter and to establish a decentralized, transnational union movement. This, we suggest, is to some extent caused by LabourStart’s centralized organizational — and thus communicational — structure. In the concluding section, we interpret our findings in broader terms relating to the context and history of labour movements, and we discuss LabourStart’s work in relation to local and global worker issues.
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| 4. |
- Eriksson Krutrök, Moa
(författare)
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Digital aftermaths of terror : reactions to terrorist attacks on twitter
- 2020
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Background. This thesis explores digital public reactions to terrorist attacks, and specifically how discourses on terrorism become articulated on social media. The overarching aim of the thesis is to explore the reactions spread on social media following attacks, and how these digital platforms may alter or transform the ways in which such attacks are collectively understood and interpreted. It explores issues relating to Twitter as a platform for backchannel meaning making, for downplaying fear mongering practices, the ways different terrorist attacks become co-articulated, as well as the divided attention of networked publics during terror-related events.Methods. The thesis is made up of four individual papers, each exploring digital reactions to different terrorist attacks on Twitter. The cases include the Utøya massacre in Norway 2011, the Stockholm lorry attack in 2017, 12 different attacks occurring between 2015-2017 in Europe (multi-case study), and the terrorist attack in Sinai, Egypt and the subsequent false alarm about a suspected terrorist attack on Oxford Street Underground station in London, UK, occuring on the same day in 2017. A combination of methods used in this thesis include network analysis of hashtag co-occurrences, and thematic analysis of prominent themes in tweets, using discourse theory as its analytical framework in the qualitative readings. Results. The findings of the thesis suggest that discourses on terrorism on social media are shaped by the specific logics present in the connective action of networked publics. The political action of digital audiences is performed in a personalised way that shapes terrorism discourse. How terrorism is understood is influenced by collective ideas of how societies become affected by trauma or resilience, and digital communities engage in downplaying or amplifying practices for such articulations. Prevailing spatial and temporal contexts alsomatter for the ways in which terrorist attacks are understood and reimagined. The (real or perceived) closeness to the attack, the interrelatedness of attacks, and aspects of virality of information plays a role in how terror discourses become articulated in digital spaces. Conclusion. This thesis makes theoretical and empirical contributions to the understanding of how digital audiences articulate terrorism discourse in the aftermath of terrorist attacks. It stresses that emotive personal expressions on social media should be understood as a highly politicised reaction, relating to a vast range of issues, such as immigration control, nationalism, or an increased prevalence of everyday racism. On social media, audiences may both amplify or downplay attention to specific terrorist attacks, and, as such, may choose to provide (or not provide) attention. Social media may thus function as a space for everyday political action in times of terrorism.
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| 5. |
- Gopalakrishnan, Shyam, et al.
(författare)
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The population genomic legacy of the second plague pandemic
- 2022
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Ingår i: Current Biology. - : Elsevier. - 0960-9822 .- 1879-0445. ; 32:21, s. 4743-4751.e6
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Tidskriftsartikel (refereegranskat)abstract
- Human populations have been shaped by catastrophes that may have left long-lasting signatures in their genomes. One notable example is the second plague pandemic that entered Europe in ca. 1,347 CE and repeatedly returned for over 300 years, with typical village and town mortality estimated at 10%–40%.1 It is assumed that this high mortality affected the gene pools of these populations. First, local population crashes reduced genetic diversity. Second, a change in frequency is expected for sequence variants that may have affected survival or susceptibility to the etiologic agent (Yersinia pestis).2 Third, mass mortality might alter the local gene pools through its impact on subsequent migration patterns. We explored these factors using the Norwegian city of Trondheim as a model, by sequencing 54 genomes spanning three time periods: (1) prior to the plague striking Trondheim in 1,349 CE, (2) the 17th–19th century, and (3) the present. We find that the pandemic period shaped the gene pool by reducing long distance immigration, in particular from the British Isles, and inducing a bottleneck that reduced genetic diversity. Although we also observe an excess of large FST values at multiple loci in the genome, these are shaped by reference biases introduced by mapping our relatively low genome coverage degraded DNA to the reference genome. This implies that attempts to detect selection using ancient DNA (aDNA) datasets that vary by read length and depth of sequencing coverage may be particularly challenging until methods have been developed to account for the impact of differential reference bias on test statistics.
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| 6. |
- Granström, Reine, et al.
(författare)
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CFD modelling of the flow through a grate-kiln
- 2009
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Ingår i: Proceedings from Seventh International Conference on Computational Fluid Dynamics in Minerals and Process Industries.
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Konferensbidrag (refereegranskat)abstract
- As part of an investigation regarding secondary reduction of NOx emissions in a grate-kiln iron ore pelletizing plant, the aim of this specific research is to develop a CFD model that enhances the understanding of the aerodynamics and mixing of species inside the rotary kiln. At first, a parametric study of the pure airflow through the kiln is carried out and for certain conditions, a transient behaviour similar to that of vortex shedding was observed, with a dependence on momentum flux ratio between the secondary air jets. Further, the development of a preliminary coal combustion model is set out, which is in need of continued work in order to produce reliable predictions of various parameters relevant to the reduction process. However, the effect of the combustion on the flow field is limited, indicating that the pure airflow model can be used to broadly investigate the influence of the secondary air flow.
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| 7. |
- Holgersson, Georg, et al.
(författare)
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A phase I pilot study of the insulin-like growth factor 1 receptor pathway modulator AXL1717 in combination with gemcitabine HCl and carboplatin in previously untreated, locally advanced, or metastatic non-small cell lung cancer
- 2015
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Ingår i: Medical Oncology. - : Springer Science and Business Media LLC. - 1357-0560 .- 1559-131X. ; 32:4
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Tidskriftsartikel (refereegranskat)abstract
- AXL1717 is an orally bioavailable IGF-1R pathway modulator that has been shown to have anti-tumoral effects. The objectives of the present study were to define maximum tolerated dose and the recommended phase II dose (RPTD) of AXL1717 in combination with gemcitabine HCl and carboplatin in non-small cell lung cancer (NSCLC). Patients with previously untreated, locally advanced, or metastatic NSCLC (squamous cell cancer or adenocarcinoma) in good performance status and with preserved major organ functions were enrolled in the study. The study was an open-label phase I study with planned cohorts of three patients per dose level of AXL1717 (215, 290, and 390 mg BID). In total, 12 patients were enrolled in the study, and of these, two were prematurely excluded. AXL1717 was administered at one dose level, 215 mg BID. A total number of 81 unique adverse events were reported. Bone marrow toxicity was reported in 10 out of 12 patients, and this organ class showed the largest number of related events. AXL1717 in combination with gemcitabine HCl and carboplatin is a possible treatment approach in previously untreated, locally advanced, or metastatic non-small cell lung cancer. However, due to the bone marrow toxicity profile shown in the present study, further dose increases of AXL1717 above 215 mg BID will probably not be feasible. Therefore, 215 mg BID constitutes maximum tolerated dose and RPTD.
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| 8. |
- Holgersson, Georg, et al.
(författare)
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Swedish lung cancer radiation study group: the prognostic value of anaemia, thrombocytosis and leukocytosis at time of diagnosis in patients with non-small cell lung cancer
- 2012
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Ingår i: Medical Oncology. - : Humana Press (Springer Imprint). - 1357-0560 .- 1559-131X. ; 29:5, s. 3176-3182
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Tidskriftsartikel (refereegranskat)abstract
- There is a need to improve the prognostic and predictive indicators in non-small cell lung cancer (NSCLC). At present, the main focus is on genetic predictive markers while the prognostic value of the standard blood variables related to haematopoiesis has been subjected to relatively limited attention. To study the prognostic potential of haemoglobin (Hgb), platelet (Plt) and white blood cell (WBC) levels at time of diagnosis in NSCLC patients, 835 NSCLC patients, stage I-IV, who received radiotherapy with curative intention (andgt; 50 Gy), were included in the study. WBC, Plt, Hgb, gender, age at diagnosis, stage, surgery and first-line chemotherapy were studied in relation to overall survival. For patients with Hgb andlt; 110 g/L and Hgb a parts per thousand yen 110 g/L), the median survival was 11.2 and 14.5 months, respectively (p = 0.0032). For WBC andgt; 9.0 x 10(9)/L and andlt; 9.0 x 10(9)/L, the median survival was 11.6 and 15.4 months, respectively (p andlt; 0.0001). For Plt andgt; 350 x 10(9)/L and andlt; 350 x 10(9)/L, the median survival was 11.2 and 14.9 months, respectively (p andlt; 0.0001). The median survival in patients with pathological results in all three markers was half of that in patients with normal levels of all three markers (8.0 and 16.0 months, respectively (p andlt; 0.0001). The level of the three studied haematological biomarkers corresponds significantly to outcome in NSCLC. These results indicate that standard haematological variables may be used as guidance for the clinician in the decision-making regarding treatment intensity and patient information.
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| 9. |
- Holgersson, Georg, et al.
(författare)
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The value of induction chemotherapy for survival in patients with non-small cell lung cancer treated with radiotherapy.
- 2012
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Ingår i: Anticancer research. - : The International Institute of Anticancer Research. - 1791-7530 .- 0250-7005. ; 32:4, s. 1339-46
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Tidskriftsartikel (refereegranskat)abstract
- AIM: The aim of the present study was to retrospectively investigate the impact of induction chemotherapy on treatment outcome in patients treated with curatively intended radiotherapy for non-small cell lung cancer (NSCLC). PATIENTS AND METHODS: Patients with a diagnosed NSCLC that have been subjected to curatively intended irradiation (≥50 Gy) and treated in an oncology department in Sweden during the years 1990-2000 were included in the study. Operated patients and patients having received concomitant chemotherapy were excluded. The included patients were localised by a manual search of all the oncology departments' medical records and radiation charts. RESULTS: Patients treated with induction chemotherapy (n=79) had a significantly better overall survival compared with patients treated with radiotherapy alone (p=0.0097) in a univariate Cox regression analysis. A platinum/taxane combination produced the greatest survival benefit; hazard ratio=0.49 (95% confidence interval=0.31 to 0.75). CONCLUSION: We found that patients treated with induction chemotherapy in addition to radiotherapy for NSCLC have a better overall survival than patients treated with radiotherapy alone and that the best results are achieved using a platinum/taxane combination.
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| 10. |
- Johansson, Simon, et al.
(författare)
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Gas and particle flow in a spray roaster
- 2014
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Ingår i: Journal of Applied Fluid Mechanics. - 1735-3572 .- 1735-3645. ; 7:2, s. 187-196
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Tidskriftsartikel (refereegranskat)abstract
- In the steel industry, waste hydrochloric acid is produced through the process to pickle steel slabs for removal of corrosion. Regenerated hydrochloric acid is obtained by separating the chloride gas from the waste product through spray roasting. This process also produces a by-product in the form of iron oxide which is sold to different industries. The present study is a continuation of a study arising from the need to better understand the dynamics inside the regeneration reactor, which in turn will improve possibilities to optimize the regeneration process, which to date has been manually adjusted by trial and error. In this study the velocity and temperature distribution inside the reactor is numerically modelled together with the droplet motion through the reactor. The main objective is to investigate the influence of a changed spray nozzle position on the flow characteristics of the continuous and dispersed phase, and the relation between temperature and energy efficiency and the regeneration process. Numerical models of the type of flow present in the regeneration reactor are not represented to any major extent in the literature, making the present study relevant to the engineers and researchers active in the steel industry and the application in question.
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